Matthew Jobin
Senior Bioinformatics Scientist at Basepaws- Claim this Profile
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Experience
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Basepaws
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Bioinformatics Scientist
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May 2022 - Present
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Personal Genome Diagnostics (PGDx)
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Bioinformatics Scientist
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Nov 2021 - May 2022
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Arc Bio
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United States
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Biotechnology
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1 - 100 Employee
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Bioinformatics Scientist II
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Feb 2019 - Jul 2021
• Authored deep-learning based software for thresholding and visualizing NGS-derived metagenomic data. • Led project to integrate LIMS system with bioinformatics tools, pipelines and laboratory SOP's. • Collaborated on the continual updating and validation of custom-designed NGS pipelines running on AWS instances (EC2, S3, RDS). • Developed analysis pipeline targeted at ancient/degraded genetic samples. • Worked closely with lab scientists to flexibly analyze and interpret the results of experiments. Show less
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University of California, Santa Cruz
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United States
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Higher Education
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700 & Above Employee
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Postdoctoral Scholar
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Jul 2017 - Dec 2018
• Led ancient DNA-focused investigation into the ancestry of South American populations, involving extraction and library preparation of ancient samples as well as population genetic analysis. • Authored pipeline in Python to process and perform statistical analysis on large WGS data sets by integrating: BWA, samtools, MALT, mia, SeqPrep2, Kraken, bcftools, bedtools, EIGENSTRAT, plink, ADMIXTOOLS, PMDTools. • Designed scripts for automated calling of mitochondrial and Y chromosomal haplogroups, phylogenetic tree construction, imputation, analysis and automation of ADMIXTURE runs. • Developed software for performing population genetic analyses on NGS data. • Created tools for assessing accuracy of NGS reads in metagenome analysis. Show less
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Santa Clara University
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United States
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Higher Education
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700 & Above Employee
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Lecturer, Independent Researcher
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Sep 2009 - Jul 2018
• Created Imputor software for phylogenetically-aware imputation of NGS data. Collaborated on investigation of human Y chromosomal dataset and published the results in Genome Biology and Evolution. • Designed Plexus software involving use of Gibbs sampling and model selection using Bayesian statistics. • Presented to both academic and non-academic audiences on human genetics and genomics. • Designed and taught five courses annually for the Department of Anthropology focused primarily on biological anthropology and evolution. Show less
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Stanford University
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United States
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Higher Education
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700 & Above Employee
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Lecturer, Independent Reseacher
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Jan 2008 - Jun 2011
• Created rejection algorithm software Rejector to track rare HLA allele in human population and collaborated to test hypothesis of human/Neandertal/Denisovan introgression, publishing the results in Science. • Designed and taught three courses for the Department of Anthropology and three courses for the Stanford Continuing Studies Program focused on human evolution • Created rejection algorithm software Rejector to track rare HLA allele in human population and collaborated to test hypothesis of human/Neandertal/Denisovan introgression, publishing the results in Science. • Designed and taught three courses for the Department of Anthropology and three courses for the Stanford Continuing Studies Program focused on human evolution
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Education
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Stanford University
Doctor of Philosophy (PhD), Physical and Biological Anthropology