Matias S. Ciarlantini
Researcher at Maprimed S.A.- Claim this Profile
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Español Native or bilingual proficiency
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Inglés Full professional proficiency
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Bio
Experience
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Maprimed S.A.
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Argentina
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Researcher
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Apr 2022 - Present
Research and development for the synthesis of Active Pharmaceutical Ingredients. Lab-scale production of high potency drug substances. Transfer of new technologies to the Pilot and Production Plant, advising on the implementation of processes. Synthesis of reference standards for quality control of intermediate and finished products. Research and development for the synthesis of Active Pharmaceutical Ingredients. Lab-scale production of high potency drug substances. Transfer of new technologies to the Pilot and Production Plant, advising on the implementation of processes. Synthesis of reference standards for quality control of intermediate and finished products.
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INTI
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Argentina
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Government Administration
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700 & Above Employee
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Organic Chemist
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Dec 2012 - Apr 2022
Design and synthesis of small molecules to target Protein-Protein Interaction as promising antitumor agents. Hit to Lead optimization. Multi-component reaction chemistry. Full characterization of novel compounds. Development and optimization of processes for the synthesis of Active Pharmaceutical Ingredients and New Chemical Entities. Synthesis and isolation of process impurities to be developed as reference standards for the pharmaceutical industry. Experience in the use of NMR, HPLC, LC-MS/MS, GC-MS, ITC and automated flash chromatograph. Show less
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Boehringer Ingelheim
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Germany
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Pharmaceutical Manufacturing
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700 & Above Employee
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Senior Analytical Development Analyst
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Apr 2011 - Dec 2012
Development and validation of analytical methodologies for New Chemical Entities and Drug Products analysis. Forced degradation studies of Active Pharmaceutical Ingredients. Structural elucidation of low molecular weight impurities. Use of HPLC, LC-MS/MS, GC-MS, FTIR, UV and Karl Fischer equipment, among others. GMP application in FDA and EU regulated environments. Control and maintenance of laboratory equipment. Drafting and execution of protocols. Application of ICH/FDA guidelines and standard routines used in the industry. Staff training. Coordination of internal and external suppliers. Show less
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Semi-senior Analytical Development Analyst
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Jun 2009 - Jun 2011
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Analytical Development Intern
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Jun 2008 - Jun 2009
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Education
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Universidad de Buenos Aires
PhD, Organic Chemistry -
Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires
Licenciatura en Ciencias Químicas