Experience

University of Vienna
• Austria
• Research Services
• 700 & Above Employee
• Post Doctoral Fellow at University of Vienna (Computational and Structural Biology)

  • Oct 2023 - Present


CeMM

• Hospitals and Health Care
• 1 - 100 Employee

• Pre Doctoral Fellow

  • Sep 2018 - Present

  Publications: https://pubmed.ncbi.nlm.nih.gov/?term=Meyenberg+Mathilde Publications: https://pubmed.ncbi.nlm.nih.gov/?term=Meyenberg+Mathilde



Wayne State University

• United States
• Higher Education
• 700 & Above Employee

• Graduate Research Assistant

  • Aug 2017 - May 2018

  Research stay in the pharmaceutical science department with focus on medicinal chemistry and molecular approaches to drug development. Designing innovative biochemical assays to screen for possible inhibitors of underexploited targets in antimicrobial development. - biochemical screening assay development - HTS screens - hit-to-lead and lead optimization - mechanism of action and SAR investigation - cell culture based assays, biomarkers, western blot Research stay in the pharmaceutical science department with focus on medicinal chemistry and molecular approaches to drug development. Designing innovative biochemical assays to screen for possible inhibitors of underexploited targets in antimicrobial development. - biochemical screening assay development - HTS screens - hit-to-lead and lead optimization - mechanism of action and SAR investigation - cell culture based assays, biomarkers, western blot



HygCen GmbH Centrum für Hygiene und medizinische Produktsicherheit

• Medical Technology Laboratory Assistant

  • May 2017 - Aug 2017

  Testing medical and surgical devices with cell culture based in vitro systems to ensure compliance with consumer protection standards as specified in ISO and EU directives. Testing medical and surgical devices with cell culture based in vitro systems to ensure compliance with consumer protection standards as specified in ISO and EU directives.



Warren Wilson College

• United States
• Higher Education
• 200 - 300 Employee

• Research Internship

  • Aug 2016 - Dec 2016

  "Extraction, identification, and quantitative analysis of triterpenes in black cohosh and the effect of actein and 23-epi-26-deoxyactein on breast cancer cells in vitro (MCF-7)"In this faculty led research project, I collaborated with another student working on their senior thesis. The whole project aims to characterize natural compounds and establish a library of possible lead compounds for drug development that are derived from natural products found in the biodiverse region of western North Carolina. While I extracted, purified, and quantified the triterpenes from black cohosh roots using HPLC-UV/ELSD, another student developed a microplate based scanning assay to test the effect of the natural products on the p-glycoprotein in the MCF-7 breast cancer cell line.While I mostly worked on the chemical and analytical aspect of this project, I very much enjoyed the collaborative nature of this project and hope students will continue working on building up the natural products library. Show less

• Original and Applied Research - Thesis work B.S.

  • Aug 2015 - Dec 2016

  "In silico design of antiviral compounds acting against the nucleoprotein of H1N1 and H5N1 influenza virus using Naproxen-C0 as lead compound"In this year-long self-directed thesis project, I engaged with the fundamentals of computational chemistry and drew from all aspects of my interdisciplinary education experience. Using the free computational software AutoDock Vina, I created and validated a dynamic binding model of the receptor-ligand pair and used the model to design more optimized drug candidates. The most promising structures were then examined with a computational toxicology evaluation. The most fascinating aspect of this project was the application of my chemical, physical, and biological knowledge to approach a problem on the molecular scale, which is challenging and rewarding at the same time. Show less

• Lab Assistant and Tutor

  • Jan 2015 - Dec 2016

  Warren Wilson College Work ProgramIn the WWC work program I could supplement my classroom experience with hands-on experience in the lab, working as teacher's assistant in the General Chemistry labs, and Analytical Chemistry labs. During a 15 hour work week my tasks included setting up lab experiments for classes, assisting students during lab practicals, supervising the use of analytical instrumentation, and cleaning up.In addition to the work as lab assistant, I also tutored students in a group setting or on an individual basis. Mentoring fellow students was one of the most rewarding aspects of this work, which truly highlighted the collegiate atmosphere students in our department enjoyed throughout their studies. Show less



Science and Advice for Scottish Agriculture (SASA)

• Research Internship molecular biology/ genetic analysis

  • May 2015 - Aug 2015

  "SNP assay of the Gb-Rbp-1 gene in G.pallida populations across the U.K. and the relation to pathogenicity and pathotype" Potato cyst nematodes are a common crop pest in Europe and costs an estimated 12% crop loss worldwide (1). By performing SNP analysis on a particular identified gene, Gb-Rbp-1, we hoped to find genetic labels to clearly identify the more virulent strains and thus tag the gene product as a possible molecular target for pesticides. Despite the fact that the data analysis with bionumerics dashed our hopes that there was a relation between the Gb-Rbp-1 gene and the aggressiveness of the nematodes, the true worth of this experience was not the outcome for me but how this opportunity led me to collaborate with many different departments and researchers. From the first moment of working on this project, I have felt connected to the scientific community and truly realized how international the effort behind any research is. In SASA's great work environment I learned a great deal about molecular techniques and diagnostics and directly applied and tuned methods such as PCR, next generation sequencing, and SNP analysis using a pyrosequencing approach. 1.Potato Cyst Nematode | SASA (Science & Advice for Scottish Agriculture). Available at: https://www.sasa.gov.uk/rd/pest-pathogen-diagnostics/potato-cyst-nematode. (Accessed: 18th February 2017) Show less


Physical Therapy Wöller
• Assistant Manager

  • Jun 2012 - Dec 2012