Experience

Netherlands Forensic Institute NFI

• Netherlands
• Research
• 400 - 500 Employee

• Wetenschappelijk medewerker

  • Aug 2017 - Present

  Ypenburg



Leiden University

• Netherlands
• Higher Education
• 700 & Above Employee

• Postdoc Molecular developmental genetics

  • Dec 2011 - Dec 2017

  Leiden A screening was performed on plantlets transformed with a library of artificial transcription factors to retrieve plants with an enhanced growth phenotype. The ultimate goal was to analyze RNA sequencing data to elucidate which molecular pathways are of importance to biomass fixation.

• PhD student Molecular developmental genetics

  • Dec 2007 - Nov 2011

  Leiden Several aspects of the Agrobacterium mediated transfer of proteins and T-DNA to yeast were studied. Among other topics the influence of the yeast DNA repair mechanisms on the formation of plasmids from the incoming T-DNA. In addition to this, I worked on the development of new techniques to target the incoming T-DNA to predetermined genomic loci. The effect of double stranded breaks in the genomic DNA and the effect of the nucleosome occupancy of the future genomic integration site on T-DNA… Show more Several aspects of the Agrobacterium mediated transfer of proteins and T-DNA to yeast were studied. Among other topics the influence of the yeast DNA repair mechanisms on the formation of plasmids from the incoming T-DNA. In addition to this, I worked on the development of new techniques to target the incoming T-DNA to predetermined genomic loci. The effect of double stranded breaks in the genomic DNA and the effect of the nucleosome occupancy of the future genomic integration site on T-DNA integration were assayed.



Erasmus MC

• OIO

  • Jun 2006 - Nov 2007

  Rotterdam Research on the human gastric pathogen Helicobacter pylori. This research focused mainly on the effect of the expression and phase variability of adhesive proteins (adhesins) on the disease outcome. Applied techniques: QPCR, cell culture, urease assay, tritium proliferation assay, flow cytometry.