Marianna Romzova
Field Aplication Scientist - NGS at GeneTiCA s.r.o.- Claim this Profile
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English Professional working proficiency
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Czech Native or bilingual proficiency
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Slovak Native or bilingual proficiency
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Hebrew Limited working proficiency
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Bio
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Experience
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GeneTiCA s.r.o.
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Hospitals and Health Care
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Field Aplication Scientist - NGS
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Mar 2021 - Present
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CEITEC - Central European Institute of Technology
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Czechia
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Research
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400 - 500 Employee
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Research Scientist
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Feb 2016 - Dec 2020
Project: Study of mutation spectrum and deep molecular response in Chronic Myeloid Leukemia Methods: digital PCR, next generation sequencing, single cell RNA sequencing, leukemic stem cells phenotypisation via FACS Project: Study of mutation spectrum and deep molecular response in Chronic Myeloid Leukemia Methods: digital PCR, next generation sequencing, single cell RNA sequencing, leukemic stem cells phenotypisation via FACS
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Postdoctoral Researcher
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Dec 2014 - Nov 2015
Principal investigator: Dr. Neta Erez Laboratory main focus is studying the role of Cancer-Associated Fibroblasts in tumor initiation, progression and metastasis. Project: Changes in pro-inflammatory signaling in glial cells enabling homing, survival and growth of metastatic melanoma cells Methods: FACS sorting, primary cell cultures, animal models Principal investigator: Dr. Neta Erez Laboratory main focus is studying the role of Cancer-Associated Fibroblasts in tumor initiation, progression and metastasis. Project: Changes in pro-inflammatory signaling in glial cells enabling homing, survival and growth of metastatic melanoma cells Methods: FACS sorting, primary cell cultures, animal models
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Post doctoral researcher
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Oct 2011 - Dec 2014
Principal Investigator: Prof. Ron N. Apte Laboratory main research interests: 1). Cytokine biology with special emphasis on studying Interleukin-1 (IL-1) biology 2). The role of inflammation in the malignant process. 3). Tumor therapy based on anti-inflammatory approaches. 4). The role of IL-1 in the pathogenicity and repair of heart attack (mycocardiam infarction). Project: The role of microenvironment derived interleukin-1 on tumor initiating abilities of breast cancer cells Methods: ELISA, IHC, Fluorescent Imaging, FACS, cell cultures, animal models Show less
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Post doctoral researcher
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Sep 2009 - Sep 2011
Principal Investigator: Prof. Mikael Kubista Research Laboratory of gene expression (Institute of Biotechnology AS CR in Prague, Czech Republic) is one of Europe's leading academic laboratories specialized in high-throughput gene and transcript analysis using real-time quantitative PCR. Project: High-throughput expression profiling of circulating and primary tumor cells using a panel of biomarkers for improvement of diagnostic screening in breast cancer patients Methods: multiple qPCR systems, expert RNA applications Show less
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GHC Genetics, ltd
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United Kingdom
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Consumer Services
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Head of molecular-biology laboratory/ Head of research and development
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May 2008 - Aug 2009
Private molecular biology laboratory focused on a diagnostic screening of a genetic variants associated with a multi-factorial diseases. • Molecular Diagnostics of multifactorial diseases • Illumina Microarray system, SNPs screening Private molecular biology laboratory focused on a diagnostic screening of a genetic variants associated with a multi-factorial diseases. • Molecular Diagnostics of multifactorial diseases • Illumina Microarray system, SNPs screening
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PhD Student/Research assistant
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Aug 2004 - Dec 2007
Principal Investigator: Prof. MD Marie Cerna Genetics of autoimmune diabetes mellitus Project: Relevance of new predictive genetic factors, which are underlying development of diabetic complications Methiods: DNA/RNA assays, Fragment Analysis Principal Investigator: Prof. MD Marie Cerna Genetics of autoimmune diabetes mellitus Project: Relevance of new predictive genetic factors, which are underlying development of diabetic complications Methiods: DNA/RNA assays, Fragment Analysis
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Education
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Charles University in Prague
RNDr., Molecular biology and genetics -
Charles University
Ph.D., Cell and Molecular Biology, Genetics and Virology -
Pavol Jozef Šafárik University in Košice
Mgr. (Msc.), Zoology/Animal Biology, Ecology