Experience

CNIC - Spanish National Center for Cardiovascular Research / Centro Nac. Investigaciones Cardiovasc.

• Spain
• Research Services
• 400 - 500 Employee

• Postdoctoral Researcher

  • 2019 - Present

  Development of different tools to study the pathophysiology mechanisms of titin, and how mechanical alterations of this protein in living cells can be related to sarcomere malfunction and cardiomyopathies Development of different tools to study the pathophysiology mechanisms of titin, and how mechanical alterations of this protein in living cells can be related to sarcomere malfunction and cardiomyopathies



University of Naples Federico II

• Higher Education
• 700 & Above Employee

• PhD student in Molecular Medicine and Medical Biotechnology (XXXI cycle)

  • 2015 - 2019

  Study of functional consequences of mutations which leads to assignment of pathogenicity of variants of uncertain significance

• Postgraduate student in Clinical Biochemistry

  • 2013 - 2015

  Search for mutations and/or polymorphisms associated or predisposing to cardiomyopathy using sequence analysis of sarcomeric genes and genes encoding channels voltage employees



CNIC - Spanish National Center for Cardiovascular Research / Centro Nac. Investigaciones Cardiovasc.

• Spain
• Research Services
• 400 - 500 Employee

• Long-term stay for PhD Project

  • 2017 - 2018

  Functional analysis of unknown mutations localized in coding regions of cMyBPC which cause Hypertrophic Cardiomyopathy, by Circular Dichroism, Differential scanning Calorimetry and Single-molecule Atomic Force Microscopy (AFM)

• Erasmus+ Traineeship: Cardiovascular Research Experience

  • Nov 2016 - May 2017

  Study of pathogenic mechanism in Hypertrophic Cardiomyopathy caused by mutations in MYBPC3 with AFM and minigene assays



Department of Biochemistry and Medical Biotechnology of the University of Naples Federico II.

• Naples

• Graduate internship

  • Sep 2009 - Mar 2012

  During my internship, I have carried out the following studies: - Study of the antiproliferative effects of carnosine on cells of colorectal carcinoma HCT116. Carnosine is a dipeptide widely distributed in the brain, kidney, stomach and especially in skeletal muscle. Recent studies have shown that carnosine has an important antitumor function in addition to having antioxidant properties, anti-aging, antiglicosilante, neuroprotective and photoprotective. - Study photoprotective action of natural antioxidants against DNA damage caused by exposure to ultraviolet radiation UVB through the technique of real-time PCR and comet assay. Show less