Mari Bonde
Senior Scientist at Quretech Bio AB- Claim this Profile
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Bio
Experience
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QureTech Bio AB
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Sweden
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Research Services
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1 - 100 Employee
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Senior Scientist
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Oct 2018 - Present
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Umeå University
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Sweden
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Higher Education
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700 & Above Employee
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Postdoc
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Aug 2015 - Jul 2018
In this project, we work with newly synthesized small molecules, compounds, potent in killing MRSA and VRE. Two important Gram+ antibiotic resistant bacteria causing hospital-acquired infections. My task is primarily to find the target protein of our compounds with research in the field of chemical proteomics. I use tool-compounds in target protein enrichment. Quantitative mass spectrometry analysis is performed to identify the isolated target protein. Potential hits are followed up with a molecular biology approach. Functional assays, making and analysing mutants and CETSA are some of the techniques used to confirm the target protein. Finding the target protein will help us to explain the mechanism of action of the compounds and hence take us one step closer to a new treatment for antibiotic resistant bacteria.
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Umeå University
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Sweden
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Higher Education
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700 & Above Employee
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Ph.D. student
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Jun 2008 - Jun 2015
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Teaching Assistant
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2008 - 2015
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Vasa centralsjukhus | Vaasan keskussairaala
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Finland
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Hospitals and Health Care
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100 - 200 Employee
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Cellbiologist
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Jun 2007 - Aug 2007
I worked with immunohistochemical and fluorescence staining of various types of tissues. I also prepared muscle biopsies for further neuropathological analysis. I worked with immunohistochemical and fluorescence staining of various types of tissues. I also prepared muscle biopsies for further neuropathological analysis.
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Vasa centralsjukhus | Vaasan keskussairaala
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Finland
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Hospitals and Health Care
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100 - 200 Employee
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Laboratory Technician
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Jun 2006 - Aug 2006
I worked with histochemical staining of various types of tissues. I worked with histochemical staining of various types of tissues.
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Education
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Umeå University
Doctor of Philosophy - PhD, Faculty of Medicine -
Umeå University
Master's degree, Molecular Biology