Mahdi Ramezani

Director of Research and Development at On Demand Pharmaceuticals Inc
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Contact Information
us****@****om
(386) 825-5501
Location
Rockville, Maryland, United States, US
Languages
  • English -
  • Persian -
  • Arabic -
  • German -

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Experience

    • United States
    • Pharmaceutical Manufacturing
    • 1 - 100 Employee
    • Director of Research and Development
      • Dec 2022 - Present

      Leading a team of young engineers for creating the future of pharmaceutical compoundingInnovating the capability of rapid formulation and filling of a large portfolio of IV medicines in response to medicine shortagesExperienced in compounding for sterile preparations based on USP <797>Experienced in manufacturing for sterile IV injectables based on 21 CFR Part 211 for current Good Manufacturing Practices (cGMP)

    • Principal Scientist
      • Nov 2021 - Dec 2022

      Leading the formulation team for development of two IV injectable medicines based on QbDLeading the engineering team for design and development of a proprietary device used for automated formulation of two IV injectable medicinesManagement of a multifaceted project using a phase gate approach Efficient communication between different stakeholders including leadership, management, formulation, engineering, systems engineering, manufacturing, materials, analytical, quality, and regulatory teams Show less

    • Senior Scientist
      • Jul 2020 - Nov 2021

      Leading a team of chemical engineers, mechanical engineers, and electrical engineers for design and development of the very first GMP drug product manufacturing platform of the companyProcess development for production of 3 Intravenous Medicines (IV-Meds) accounting for compatibility, stability, mixing, filtering, sterilization, filling, and finishingIncorporation of ICH and CFR guidelines for QbD and GMP pharmaceuticals manufacturing Successful design of several new systems from concept to prototype resulting in 3 patents in the first year Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Flow Chemist, Research Scientist
      • Jun 2018 - Jul 2020

      • Fundamental reaction studies of hydroformylation, transfer hydrogenation, and carbonylation • Design, prototype, automation, and control of lab scale high-throughput flow chemistry platforms • Automated investigation of the role of catalysts, substrates, solvents, temperature, pressure, and mixing on chemical reactions at high pressures and temperatures • Comparison of the performance of batch and flow reactors for various single-phase (liquid only) or two-phase (gas-liquid) catalytic reactions • Continuous manufacturing of chemicals, specifically aldehydes, anhydrides, and ketals • Reaction screening and optimization using statistical methods including machine learning • Automated kinetic and mechanistic chemical reaction studies for pathway analysis and optimization of reaction to achieve yield and selectivity of fine chemicals • Automated in-flow Quantum Dot (QD) nanoparticle screening, optimization, and synthesis • Autonomous synthesis of single crystal quantum dots using machine learning optimization algorithms • Consultation on mechanical designs, technical drawings, and LabVIEW automation • Experience with application and method development of HPLC, ELSD, GC, MS, and NMR Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Scientist
      • Oct 2016 - Jul 2017

      • Development of the novel infiltration diagnosis method of Phase-change Enhanced Cooling Infrared Thermography (PECIT) • Design and manufacture of the proof of concept • Programming the model for infiltration detection using MATLAB • Feasibility study for production and commercialization of PECIT • Preparation of the Product Requirements Document (PRD) • Development of the novel infiltration diagnosis method of Phase-change Enhanced Cooling Infrared Thermography (PECIT) • Design and manufacture of the proof of concept • Programming the model for infiltration detection using MATLAB • Feasibility study for production and commercialization of PECIT • Preparation of the Product Requirements Document (PRD)

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Assistant, Group Manager
      • Sep 2011 - Aug 2016

      • Design and manufacturing of optically clear flow reactors for multiphase flow studies• Setup and application of two- and three-dimensional Particle Image Velocimetry (PIV)• Setup and application of Planar Laser Induced Fluorescence (PLIF) for species transport measurement• Non-invasive measurement of mass transfer and dispersed phase size and shape in two phase flow• Investigation of fluidized particle beds and Taylor-Couette reactors• Scale up of a microreactor to lab scale and investigation of changes in characteristics• Data collection and analysis using parallel processing Show less

    • Graduate Teaching Assistant
      • Jan 2015 - Jul 2016

      I taught the Fluid Mechanics Laboratory course for the Mechanical Engineering department. I recently won a Teaching Excellence Award in ISU recognizing great reviews from course instructors and exceptional student feedbacks I received. I was appointed as the material development TA for this course for the spring semester of 2016, reviewing and revising the procedures and manuals of experiments.

    • Research Assistant and Senior Engineer
      • Aug 2007 - May 2010

      • Supervision of a team of 14 engineers • Diesel engine combustion and spray simulation and integration with in-house engine performance simulation code • Manager on the technology transfer of a heavy-duty Diesel engine • Feasibility study for development of light duty Diesel engines for passenger cars in Iran • Supervision of a team of 14 engineers • Diesel engine combustion and spray simulation and integration with in-house engine performance simulation code • Manager on the technology transfer of a heavy-duty Diesel engine • Feasibility study for development of light duty Diesel engines for passenger cars in Iran

Education

  • Iowa State University
    Doctor of Philosophy (PhD), Mechanical Engineering, Chemical and Biological Engineering
    2011 - 2016
  • University of Tehran
    Master of Science (MSc), Mechanical Engineering
    2006 - 2008
  • Amirkabir University of Technology - Tehran Polytechnic
    Bachelor of Science (BSc), Mechanical engineering
    2002 - 2006

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