Mansi Parekh

Preclinical Manager - Epilepsy Head at Neurona Therapeutics
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
South San Francisco, California, United States, US

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

You need to have a working account to view this content.
You need to have a working account to view this content.

Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Preclinical Manager - Epilepsy Head
      • Jan 2021 - Present

      South San Francisco, California, United States

    • Scientist II
      • Jun 2018 - Dec 2020

      South San Francisco, CA

    • Scientist
      • Nov 2016 - Jun 2018

      San Francisco Bay Area

    • United States
    • Higher Education
    • 700 & Above Employee
    • Post-Doctoral Associate
      • Sep 2012 - Oct 2016

      Stanford, CA • Investigate efficacy of new pharmacological compounds including PK studies on animal models of basal cell carcinoma, stroke and TBI • Design and implement drug delivery strategies • screening compounds for drug development for the treatment of lyme disease - in both cell culture and animal models • Investigate structural brain changes due to TBI in football players with concussions and head impact using 3T diffusion MRI. • Design and implement MR acquisition techniques on 7T to… Show more • Investigate efficacy of new pharmacological compounds including PK studies on animal models of basal cell carcinoma, stroke and TBI • Design and implement drug delivery strategies • screening compounds for drug development for the treatment of lyme disease - in both cell culture and animal models • Investigate structural brain changes due to TBI in football players with concussions and head impact using 3T diffusion MRI. • Design and implement MR acquisition techniques on 7T to study brain structural and connectivity measures in the evolving diseased brain in patients with epilepsy. • Investigate brain structural changes associated with memory loss and aging using PET imaging. • Assisted in writing awarded fellowships. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Post Doctoral Associate
      • Jan 2011 - Sep 2012

      • Designed a detailed study to characterize and correlate structural connectivity changes with fMRI changes and behavioral measures of cognition and memory in patients with epilepsy • Designed and executed the acquisition protocol, and analyzed high-level diffusion MRI, for both in vivo and excised specimen to study brain structural connectivity in patients with epilepsy • Performed neuro-psychological evaluations on patients with epilepsy and autism spectrum disorder and subsequently… Show more • Designed a detailed study to characterize and correlate structural connectivity changes with fMRI changes and behavioral measures of cognition and memory in patients with epilepsy • Designed and executed the acquisition protocol, and analyzed high-level diffusion MRI, for both in vivo and excised specimen to study brain structural connectivity in patients with epilepsy • Performed neuro-psychological evaluations on patients with epilepsy and autism spectrum disorder and subsequently correlate with structural and functional MRI results • Directed and managed multiple medical device and drug preclinical studies and clinical trials • Managed regulatory compliance, patient enrollment and data for all human studies pursued in the Carney Lab • Mentored, trained and supervised graduate and undergraduate research students

    • Graduate Research Assistant
      • Aug 2005 - Dec 2010

      • Designed a controlled experiment to characterize longitudinal structural changes that occur in a rat model of temporal lobe epilepsy during epileptogenesis • Carried-out in vivo and excised rat-brain MRI at 4.7T, 11.1T and 17.6T on Bruker and Varian systems. • Performed patient-brain imaging at 3T on Siemens systems • Performed extended analysis of diffusion-weighted measurements using diffusion tensor and higher angular resolution diffusion imaging (HARDI) post-processing methods;… Show more • Designed a controlled experiment to characterize longitudinal structural changes that occur in a rat model of temporal lobe epilepsy during epileptogenesis • Carried-out in vivo and excised rat-brain MRI at 4.7T, 11.1T and 17.6T on Bruker and Varian systems. • Performed patient-brain imaging at 3T on Siemens systems • Performed extended analysis of diffusion-weighted measurements using diffusion tensor and higher angular resolution diffusion imaging (HARDI) post-processing methods; and T1 and T2 measurements • Implemented fiber tracking using HARDI post-processing methods in order to analyze connectivity changes within the limbic structures affected in temporal lobe epilepsy in both epilepsy patients and the rat model of epilepsy • Performed various histological and immunohistochemical techniques in order to assess pathological changes that take place during epileptogenesis in a rat brain • Served as a study coordinator for 2 industry-sponsored clinical trials • Trained new lab members on neuroimaging and analysis; animal surgery and tissue handling.

Education

  • University of Florida
    Ph.D, Neuroscience
    2005 - 2010
  • University of Florida
    B.S, Chemistry; an; Biochemistry
    2001 - 2005

Community

You need to have a working account to view this content. Click here to join now