Luis E. Lopez
Department Manager at Augusta University- Claim this Profile
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Bio
Credentials
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Group 1 - FDA Regulated Research
CITI Program, A Division of BRANYOct, 2018- Oct, 2024
Experience
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Augusta University
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United States
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Higher Education
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700 & Above Employee
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Department Manager
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Apr 2020 - Present
Department of Biochemistry and Molecular Biology Department of Biochemistry and Molecular Biology
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Augusta University
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United States
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Higher Education
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700 & Above Employee
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Laboratory Manager / Grant Development Specialist
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Sep 2015 - Mar 2020
Department of Biochemistry and Molecular BiologyIn addition to helping faculty and students with finding sources of funding, development of research proposals and administrative management of grants, I perform diverse managerial, technical and scientific functions in Dr. Vinata Lokeswar's Laboratory at AU's Biochemistry and Molecular Biology Department.Research: participation in ongoing federal funding projects for research in urological cancer investigating cellular mechanisms of bladder cancer progression, mechanisms of resistance to chemotherapies in prostate cancer cells and studies on prevention and control of metastatic renal cell carcinoma. The research involves western Blot analysis, DNA and RNA isolation, and cloning, tissue culture of tumor cell lines and related techniques (Matrigel Invasion assay, ELISA, tumor induction in athymic mouse models, treatment and evaluation, etc.). Evaluation of anti-tumor effects of HA-related drugs/compounds in live models both xenograft and transgenic mice.
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University of Miami Miller School of Medicine
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United States
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Higher Education
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700 & Above Employee
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Laboratory Manager / Research Associate
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Jul 2005 - Sep 2015
Department of UrologyManagement responsibilities: Research projects and laboratory management. Pre- and post-award administration of Federal grants and private funding. Bladder and prostate cancer research: Understanding the mechanism of bladder and prostate cancer progression. To examine the functions of tumor-derived hyaluronidase and hyaluronic acid to exploit the expression of these molecules as cancer diagnostics and for developing novel therapeutics. Department of UrologyManagement responsibilities: Research projects and laboratory management. Pre- and post-award administration of Federal grants and private funding. Bladder and prostate cancer research: Understanding the mechanism of bladder and prostate cancer progression. To examine the functions of tumor-derived hyaluronidase and hyaluronic acid to exploit the expression of these molecules as cancer diagnostics and for developing novel therapeutics.
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University of Miami
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United States
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Higher Education
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700 & Above Employee
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Research Clinic Specialist
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Nov 1998 - Jun 2005
Department of Cell Biology and AnatomyHandling and care of a Xenopus laevis colony. Embryology laboratory: techniques of collection, manipulation and culture of frog oocytes and embryos. Dissociation and fluorescent stain for fluorescent microscopy. Isolation of Primordial Germinal Cells (PGC’s). Techniques of microinjection of RNA in oocytes and embryos at several stages of development. Department of Cell Biology and AnatomyHandling and care of a Xenopus laevis colony. Embryology laboratory: techniques of collection, manipulation and culture of frog oocytes and embryos. Dissociation and fluorescent stain for fluorescent microscopy. Isolation of Primordial Germinal Cells (PGC’s). Techniques of microinjection of RNA in oocytes and embryos at several stages of development.
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Laboratorios Ovejero S.A.
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Spain
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Technologist Supervisor for Cell Culture and Virology
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1991 - 1996
Supervising, managing and training of a multidisciplinary team focused in the production of viral veterinary vaccines and diagnostic means. Direction of production process; including operations' planning and quality control according with GMPs and GMLs. Production of viral and chlamydia agents, and antigens both ‘in vivo’ (target animals, chicken embryos) and ‘in vitro’ (cellular and tissue culture) systems. Research involving virological and immunological techniques. Participation in other processes involving vaccines production and work in biological laboratories (fluids filtration, freeze-dry, etc.).
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Quality Control Technical Supervisor/Specialist
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1987 - 1991
Development and direction of quality control processes related with vaccines and means of serological diagnostic. Validation and homologation of products and process according to standards ISO, DIN, pharmacopoeias, etc. Biochemical and quality control laboratory instrumentation: low-pressure liquid chromatography, SDS-PAGE electrophoresis, spectrophotometry UV/VIS and others. Development, calibration and evaluation of means of serological diagnostic by immunoassay (ELISA) and other advanced immunological techniques (anti-idiotypic antibodies, monoclonal antibodies, etc.). Production, characterization and certification of monoclonal antibodies for laboratory animals (specifically mice, rats, guinea pigs, rabbits, chickens and dogs) according to the procedures of the ICLAS (International Council of Animal Laboratory) in conventional systems as well as in barrier-isolation devices (Specific Pathogens Free animals).
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Education
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2016 - 2018
Augusta University-Hull College of Business
Master of Business Administration - MBA, Business Administration and Management, General -
1982 - 1987
University of Havana
Licentiate degree, Biology/Biological Sciences, General
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