Experience

ImmuONE

• United Kingdom
• Biotechnology
• 1 - 100 Employee

• Client Relationship Manager

  • Feb 2023 - Present

  Immune-specialist scientist working in Business Development. Passionate about leveraging cutting-edge immunological advancements to drive innovation and meet customer needs. Collaborating closely with internal and external technical and operational teams to ensure a holistic approach in delivering tailored solutions. Immune-specialist scientist working in Business Development. Passionate about leveraging cutting-edge immunological advancements to drive innovation and meet customer needs. Collaborating closely with internal and external technical and operational teams to ensure a holistic approach in delivering tailored solutions.



Truro and Penwith College

• United Kingdom
• Education
• 400 - 500 Employee

• Lecturer in Biology

  • Sep 2021 - Feb 2023

  In this role, I was responsible for the delivery of Biochemistry and Cell Biology lectures. In addition to this, I also taught Biology at A Level, to the AQA exam-board. I had part ownership of these classes and was responsible for the marking, planning and delivery of lessons/ lectures. In this role, I was responsible for the delivery of Biochemistry and Cell Biology lectures. In addition to this, I also taught Biology at A Level, to the AQA exam-board. I had part ownership of these classes and was responsible for the marking, planning and delivery of lessons/ lectures.



University of Bristol

• United Kingdom
• Higher Education
• 700 & Above Employee

• • Aug 2019 - Dec 2019

  In this role, I was responsible for continuing some of the work started in my PhD project. Furthermore, I optimised a DNA sequencing assay to allow the detection of interleukin-33 DNA-binding sites. I routinely performed extracellular flux, stable isotope tracing (mass spectroscopy), PCR, immunoblotting, immunoprecipitation, proteomics, and electron microscopy, in addition to image processing/analysis, statistics and bioinformatics. This work can be found at: PMID: 33884963.Furthermore, I was involved in investigating how metabolism changes in T Cells undergoing suppression with various anti-inflammatory drugs in the context of ocular auto-inflammation. Show less

• • Sep 2016 - Aug 2019

  During this project, I identified the metabolic changes in retinal pigment epithelium cells during contexts of innate immune stress. I identified the protein AMP-activated kinase as a key energetic sensor which differentially regulates the metabolic adaptations to varying innate immune signals. In addition, have identified one immune signaling molecule (interleukin-33) as a metabolic checkpoint in retinal pigment epithelium cells, acting both through extracellular signaling and through internal transcriptional regulation of glycolytic enzymes and mitochondrial pyruvate oxidation. Show less



Swansea University

• United Kingdom
• Higher Education
• 700 & Above Employee

• • May 2016 - Aug 2016

  This project involved the study of human eosinophil metabolism during quiescence and activation, understanding the differential metabolic response of eosinophils to immune signaling molecules between asthmatics and non-asthmatics. Techniques involved include primary cell culture, granulocyte isolation, extracellular flux analysis, immunosorbent assays, flow cytometry, cell viability assays, PCR and western blotting. This work can be found at: PMID: 31856334.

• • Sep 2015 - Jul 2016

  During this project, I investigated the responses of gestation-associated tissues (placenta, choriodecidua and amnion) to various innate immune stressors, assessing both cytokine output and key signaling pathways. For this, I performed dissection of human placentas, culture of primary human tissue, immunosorbent assays, immunoblotting and RT-PCR. This work can be found at: PMIDs: 28712670 and 28295207.