Experience

American Board of Medical Genetics and Genomics

• Hospitals and Health Care
• 1 - 100 Employee

• Laboratory of Genetics and Genomics (LGG) Fellow _ Board eligible

  • Jul 2021 - Present

  Two-year LGG training program _ NHGRI sponsored • Received comprehensive training experience on interpretation and report writing of clinical cases using Karyotyping, Cytogenetics, Sanger sequencing, Whole Exome Sequencing, Whole genome sequencing. Being involved in case sign-out GC counseling. • Build knowledges on medical genetics, developmental biology and dysmorphology, inborn errors of metabolism, and current concepts in clinical molecular genetics and molecular diagnostics… Show more Two-year LGG training program _ NHGRI sponsored • Received comprehensive training experience on interpretation and report writing of clinical cases using Karyotyping, Cytogenetics, Sanger sequencing, Whole Exome Sequencing, Whole genome sequencing. Being involved in case sign-out GC counseling. • Build knowledges on medical genetics, developmental biology and dysmorphology, inborn errors of metabolism, and current concepts in clinical molecular genetics and molecular diagnostics. Transcript is available upon request. • Participate and provide critical appraisals at weekly discussion on clinical genetic cases, cytogenetics/molecular genetics sign-out, and peer review of latest journal articles to maintain an awareness of latest development in human genetic and genomic medicine. • Gain immersive experiences in clinical laboratory operation, management, and regulations via rotating at various CLIA certified laboratories of National Institutes of Health (NIH), the children’s national medical center, and three private vendors. • Acquire intense clinical exposure in various NIH centers, hospitals and outpatient clinics that generally involves patient contact and genetic counseling. • Teach lectures on genetic topic on rare diseases. This is a 2-hr virtual lecture to a small group of medical students at Georgetown University School of Medicine. Show less Two-year LGG training program _ NHGRI sponsored • Received comprehensive training experience on interpretation and report writing of clinical cases using Karyotyping, Cytogenetics, Sanger sequencing, Whole Exome Sequencing, Whole genome sequencing. Being involved in case sign-out GC counseling. • Build knowledges on medical genetics, developmental biology and dysmorphology, inborn errors of metabolism, and current concepts in clinical molecular genetics and molecular diagnostics… Show more Two-year LGG training program _ NHGRI sponsored • Received comprehensive training experience on interpretation and report writing of clinical cases using Karyotyping, Cytogenetics, Sanger sequencing, Whole Exome Sequencing, Whole genome sequencing. Being involved in case sign-out GC counseling. • Build knowledges on medical genetics, developmental biology and dysmorphology, inborn errors of metabolism, and current concepts in clinical molecular genetics and molecular diagnostics. Transcript is available upon request. • Participate and provide critical appraisals at weekly discussion on clinical genetic cases, cytogenetics/molecular genetics sign-out, and peer review of latest journal articles to maintain an awareness of latest development in human genetic and genomic medicine. • Gain immersive experiences in clinical laboratory operation, management, and regulations via rotating at various CLIA certified laboratories of National Institutes of Health (NIH), the children’s national medical center, and three private vendors. • Acquire intense clinical exposure in various NIH centers, hospitals and outpatient clinics that generally involves patient contact and genetic counseling. • Teach lectures on genetic topic on rare diseases. This is a 2-hr virtual lecture to a small group of medical students at Georgetown University School of Medicine. Show less



National Institute on Deafness and Other Communication Disorders

• 1 - 100 Employee

• Biologist

  • Mar 2018 - Present

  • Management: 1. Maintain research equipment performance by establishing quality standards; establish service contract on equipment replacement, service and repair. 2. Track and report key functional metrics to reduce expenses and improve effectiveness in research. 3. Monitor and forecast upcoming levels of demand and seek and partner with reliable vendors and suppliers. negotiate with vendors to ensure budge limit is met. 4. Familiar with the NIH Procurement and Purchasing… Show more • Management: 1. Maintain research equipment performance by establishing quality standards; establish service contract on equipment replacement, service and repair. 2. Track and report key functional metrics to reduce expenses and improve effectiveness in research. 3. Monitor and forecast upcoming levels of demand and seek and partner with reliable vendors and suppliers. negotiate with vendors to ensure budge limit is met. 4. Familiar with the NIH Procurement and Purchasing On-line Tracking System (POTS) system. 5. Prepare annual lab safety survey, annual animal safety survey and annual equipment certification. 6. Ensure research staff compliance with NIH policies. • Mentorship: 1. Provides guidance, leadership, and training in basic and preclinical studies to research team members including postdocs, postbacs, and visiting fellows. 2. Troubleshooting experimental procedures; lead and advise on research presentations including manuscript and conference poster. • Research projects and achievements: 1. Implemented a semi-automated quantification method on 3-D imaging of cells in the adult mouse utricle, a milestone that will impact the evaluation on cell survival and regeneration. The method has been published and selected as cover page story with one of the confocal images. 2. Established protein analysis protocol in secreted exosome in inner ear. The finding has been published in a prestigious journal: Journal of Clinical Investigation. 3. Conducted preclinical studies to investigate the mechanism and evaluate the co-therapy strategies in patients on Cisplatin chemotherapy using mouse model and cancer patients’ data. This finding has been published. 4. Established in-situ co-detection protocol of microRNA and protein in whole inner ear. Leading research project to investigate the role of microRNA in ototoxicity caused by amino-glycoside and cisplatin. • Journal review: Reviewer for prestigious journals: Cancer Letters, and Journal of Cancer Therapy. Show less • Management: 1. Maintain research equipment performance by establishing quality standards; establish service contract on equipment replacement, service and repair. 2. Track and report key functional metrics to reduce expenses and improve effectiveness in research. 3. Monitor and forecast upcoming levels of demand and seek and partner with reliable vendors and suppliers. negotiate with vendors to ensure budge limit is met. 4. Familiar with the NIH Procurement and Purchasing… Show more • Management: 1. Maintain research equipment performance by establishing quality standards; establish service contract on equipment replacement, service and repair. 2. Track and report key functional metrics to reduce expenses and improve effectiveness in research. 3. Monitor and forecast upcoming levels of demand and seek and partner with reliable vendors and suppliers. negotiate with vendors to ensure budge limit is met. 4. Familiar with the NIH Procurement and Purchasing On-line Tracking System (POTS) system. 5. Prepare annual lab safety survey, annual animal safety survey and annual equipment certification. 6. Ensure research staff compliance with NIH policies. • Mentorship: 1. Provides guidance, leadership, and training in basic and preclinical studies to research team members including postdocs, postbacs, and visiting fellows. 2. Troubleshooting experimental procedures; lead and advise on research presentations including manuscript and conference poster. • Research projects and achievements: 1. Implemented a semi-automated quantification method on 3-D imaging of cells in the adult mouse utricle, a milestone that will impact the evaluation on cell survival and regeneration. The method has been published and selected as cover page story with one of the confocal images. 2. Established protein analysis protocol in secreted exosome in inner ear. The finding has been published in a prestigious journal: Journal of Clinical Investigation. 3. Conducted preclinical studies to investigate the mechanism and evaluate the co-therapy strategies in patients on Cisplatin chemotherapy using mouse model and cancer patients’ data. This finding has been published. 4. Established in-situ co-detection protocol of microRNA and protein in whole inner ear. Leading research project to investigate the role of microRNA in ototoxicity caused by amino-glycoside and cisplatin. • Journal review: Reviewer for prestigious journals: Cancer Letters, and Journal of Cancer Therapy. Show less



National Cancer Institute (NCI)

• United States
• Research Services
• 700 & Above Employee

• Visting Scientist

  • Nov 2010 - Mar 2018

  Designed, executed, and analyzed results of mouse experiments. Managed lab operations, budget, inventory, and equipment maintenance. Prepared grant proposals. Drafted, edited, submitted, and revised manuscripts, detailing research findings. Prepared posters and deliver presentations on research discoveries at annual scientist seminars and conferences. Mentored lab technicians and junior post-doctoral researchers in revising manuscripts. The major projects and duties are listed… Show more Designed, executed, and analyzed results of mouse experiments. Managed lab operations, budget, inventory, and equipment maintenance. Prepared grant proposals. Drafted, edited, submitted, and revised manuscripts, detailing research findings. Prepared posters and deliver presentations on research discoveries at annual scientist seminars and conferences. Mentored lab technicians and junior post-doctoral researchers in revising manuscripts. The major projects and duties are listed below: • Analysis of the de novo function of the oncogene Vav1 that will lead to age or stress associated endothelial dysfunction in various mouse models (LDLR deficiency, ApoE KO and ob/ob) : In collaboration with Dr. Dan Berkowitz, head of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine. This work received Fellows Award for Research Excellence (FARE) of the National Institutes of Health (NIH). • Discovered Novel function of a GAP protein (Vav1) in the development of childhood obesity. This work has been published in Stem Cells. • Understood the mechanism behind the radiotherapy-resistance of pancreatic cancer and breast cancer using human pancreatic and breast cancer cell lines and later xenograft in nude mice as model systems. A lysosomal–mediated protein renewal / instability is tightly associated with the aggressiveness of the cancer. • Organizing Fellows and Young Investigators Seminar Series. Inviting renowned scientists to present their key findings to postdoctoral fellows in this bi-monthly seminar. • Served as reviewer for prestigious journals in cancer research: Cancer Letters, Plos One, and Journal of Cancer Therapy. Show less Designed, executed, and analyzed results of mouse experiments. Managed lab operations, budget, inventory, and equipment maintenance. Prepared grant proposals. Drafted, edited, submitted, and revised manuscripts, detailing research findings. Prepared posters and deliver presentations on research discoveries at annual scientist seminars and conferences. Mentored lab technicians and junior post-doctoral researchers in revising manuscripts. The major projects and duties are listed… Show more Designed, executed, and analyzed results of mouse experiments. Managed lab operations, budget, inventory, and equipment maintenance. Prepared grant proposals. Drafted, edited, submitted, and revised manuscripts, detailing research findings. Prepared posters and deliver presentations on research discoveries at annual scientist seminars and conferences. Mentored lab technicians and junior post-doctoral researchers in revising manuscripts. The major projects and duties are listed below: • Analysis of the de novo function of the oncogene Vav1 that will lead to age or stress associated endothelial dysfunction in various mouse models (LDLR deficiency, ApoE KO and ob/ob) : In collaboration with Dr. Dan Berkowitz, head of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine. This work received Fellows Award for Research Excellence (FARE) of the National Institutes of Health (NIH). • Discovered Novel function of a GAP protein (Vav1) in the development of childhood obesity. This work has been published in Stem Cells. • Understood the mechanism behind the radiotherapy-resistance of pancreatic cancer and breast cancer using human pancreatic and breast cancer cell lines and later xenograft in nude mice as model systems. A lysosomal–mediated protein renewal / instability is tightly associated with the aggressiveness of the cancer. • Organizing Fellows and Young Investigators Seminar Series. Inviting renowned scientists to present their key findings to postdoctoral fellows in this bi-monthly seminar. • Served as reviewer for prestigious journals in cancer research: Cancer Letters, Plos One, and Journal of Cancer Therapy. Show less



Verihealthy LLC

• Urbana, Maryland

• Project Manager

  • Nov 2015 - Mar 2017

  Supported genetic testing for start-up company. Established genetic studies on cardiovascular disease. Spearheaded project planning, execution, and troubleshooting. Provide direction and guidance to study team. Coordinated research and consulting activities and liaised with study sponsors and collaborating investigators. • Positioned company for cancer and cardiovascular genetic research by establishing statement of work and coordinating research team. Collaborated with study sponsors to… Show more Supported genetic testing for start-up company. Established genetic studies on cardiovascular disease. Spearheaded project planning, execution, and troubleshooting. Provide direction and guidance to study team. Coordinated research and consulting activities and liaised with study sponsors and collaborating investigators. • Positioned company for cancer and cardiovascular genetic research by establishing statement of work and coordinating research team. Collaborated with study sponsors to understand objectives and initiate study protocols; led project management; trained successor on processes. Show less Supported genetic testing for start-up company. Established genetic studies on cardiovascular disease. Spearheaded project planning, execution, and troubleshooting. Provide direction and guidance to study team. Coordinated research and consulting activities and liaised with study sponsors and collaborating investigators. • Positioned company for cancer and cardiovascular genetic research by establishing statement of work and coordinating research team. Collaborated with study sponsors to… Show more Supported genetic testing for start-up company. Established genetic studies on cardiovascular disease. Spearheaded project planning, execution, and troubleshooting. Provide direction and guidance to study team. Coordinated research and consulting activities and liaised with study sponsors and collaborating investigators. • Positioned company for cancer and cardiovascular genetic research by establishing statement of work and coordinating research team. Collaborated with study sponsors to understand objectives and initiate study protocols; led project management; trained successor on processes. Show less



McMaster University

• Canada
• Higher Education
• 700 & Above Employee

• Researcher PHD Student

  • Sep 2004 - Sep 2010

  Managed cancer research projects on role of the transcription factor upon cancer initiation using Rous sarcoma virus (RSV) and microarray analysis in primary cells. Drafted, submitted, and revised manuscripts. Facilitated grant writing. • Enabled discoveries related to the loss of function of a specific gene and authored three related publications. Created first-time retroviral-based gene delivery and shRNA expression system for chicken embryonic fibroblast system, demonstrating damage… Show more Managed cancer research projects on role of the transcription factor upon cancer initiation using Rous sarcoma virus (RSV) and microarray analysis in primary cells. Drafted, submitted, and revised manuscripts. Facilitated grant writing. • Enabled discoveries related to the loss of function of a specific gene and authored three related publications. Created first-time retroviral-based gene delivery and shRNA expression system for chicken embryonic fibroblast system, demonstrating damage to gene of interest in primary cells; still in use and leveraged to conduct research and prepare publications. • Won Best Poster Presentation Award at the MGH-HKU-Nature China Forum 2007-Molecular Medicine and Biopharma Opportunities and received 2 travel scholarships. Show less Managed cancer research projects on role of the transcription factor upon cancer initiation using Rous sarcoma virus (RSV) and microarray analysis in primary cells. Drafted, submitted, and revised manuscripts. Facilitated grant writing. • Enabled discoveries related to the loss of function of a specific gene and authored three related publications. Created first-time retroviral-based gene delivery and shRNA expression system for chicken embryonic fibroblast system, demonstrating damage… Show more Managed cancer research projects on role of the transcription factor upon cancer initiation using Rous sarcoma virus (RSV) and microarray analysis in primary cells. Drafted, submitted, and revised manuscripts. Facilitated grant writing. • Enabled discoveries related to the loss of function of a specific gene and authored three related publications. Created first-time retroviral-based gene delivery and shRNA expression system for chicken embryonic fibroblast system, demonstrating damage to gene of interest in primary cells; still in use and leveraged to conduct research and prepare publications. • Won Best Poster Presentation Award at the MGH-HKU-Nature China Forum 2007-Molecular Medicine and Biopharma Opportunities and received 2 travel scholarships. Show less