Experience

Immunophage Biotech Co. Ltd.

• China
• Biotechnology Research
• 1 - 100 Employee

• MD, PhD, Associate Director of the Dept. of Pharmacology & Biology

  • Apr 2021 - Present



The Affiliated Hospital of Nanjing University of Chinese Medicine

• Nanjing, Jiangsu, China

• Postdoctoral Researcher

  • Jul 2018 - Present

  • Conceived and conducted independent research projects directed at epigenetic regulation of insulin resistance, energy expenditure in obesity and type 2 diabetes to develop new tools for the treatment of metabolic diseases • Developed several tissue specific gene knockout / overexpressed animal models to investigate how epigenetic signatures are altered in obesity and type 2 diabetes • Performed high-throughput genome analysis techniques and computational biological methods (GSEA analysis, TCGA Datasets, Python & R programming language, etc.) to predict and to improve the ability to diagnose, treat, and prevent metabolic diseases Show less



UC Irvine

• United States
• Higher Education
• 700 & Above Employee

• Assistant Specialist

  • Jan 2017 - Nov 2020

  • Conducted independently and worked cross-functionally on the project of “Lysine-specific Demethylase 1 (LSD 1) regulates mitochondrial biogenesis and function and the effects and mechanism on energy, fat and glucose metabolism”, which aims to investigate the mechanism and potential new targets for the treatment of obesity and diabetes • Constructed and synthesized the antisense-oligonucleotides (ASO) and thyroid hormone T3 conjugates for obesity treatment following the principle of antibody-drug conjugates • Participated in the research of several projects such as “Nicotinamide N-methyltransferase is a novel regulator of energy expenditure”, “Epigenetic regulation of mitochondrial homeostasis and energy metabolism” • Collaborated with UCI Center for the Study of Cannabis to demonstrate physiological and metabolic roles of the endogenous cannabinoid system Show less



The Affiliated Hospital of Nanjing University of Chinese Medicine - Central Laboratory & GCP Center

• Nanjing, Jiangsu, China

• Graduate Research Assistant

  • Jul 2014 - Dec 2016

  • Acquired training in in-vivo experimental skills, such as intravenous injection of the adeno-associated virus via the tail of mouse, the establishment of hyperglycemia-induced chronic wound rat model • Acquired the certificate of Good Clinical Principle (GCP) Training and participated in some certain clinical trials (Phase I – Phase IV) • Participated in the projects on “Total Flavones extracted from Abelmoschus Manihot L.Medic improves hind limbs ischemia injury via PI3K/Akt pathway”, “Abelmoschus Manihot as a component of Chuang-Ling-Ye accelerates ischemic wounds healing by vascular endothelial growth factor” Show less