Experience

Polysciences, Inc.

• United States
• Biotechnology Research
• 100 - 200 Employee

• Analytical Team Leader, R&D

  • Sep 2021 - Present

  • Interface with customers, business leaders, R&D project leaders and other functional groups to develop new project and achieve financial targets. • Lead and mentor analytical team to develop cGMP analytical methods and improve the efficiency, accuracy, robustness of existing analytical methods. • Support QC department with method validation and equipment maintenance. • Develop, optimize analytical methods and recommend equipment to improve analytical capabilities, and support new product development activities. Show less



Wilmington PharmaTech Company LLC

• United States
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Senior Analytical Scientist

  • Jun 2017 - Sep 2021

  Expertise in method transfer, development and validation for GMP/GLP production process, API release and stability test. Perform analytical chemistry work effectively and accurately to ensure the identity, purity, quality and potency of product by following validated test method and procedures. Provide analytical advice and technical consultation for process optimization, intermediate and impurity identification. Write and update protocols, procedures and reports with internal documentation template. Review notebook, records, reports and documentation for completeness and accuracy in accordance with cGMP, internal document standards. Show less



Veritas Laboratories

• Tifton, GA

• Lab Scientist

  • Feb 2014 - Apr 2017

  Develop and validate an analytical method for quantifying 78 analytes including drugs like oxycodone, hydrocodone, morphine, THC etc and their major metabolites. Lead a LC-MS/MS method development project for quantification of both alcohol biomarkers and barbitals. Develop an LC-MS/MS confirmation method for 6 barbitals. Transfer and optimize LC-MS/MS analytical method for chiral separation of methamphetamine enantiomers. Assist in set up and update of LIMS system. Supervising two PhD scientists and two MLT for the operation of urine drug test (UDT) and oral drug test (ODT). Ensure that State/CLIA regulation and SOPs are followed in all bioanalytical services of UDT and ODT. Maintains records, reports, QA and QC documentation with LIMS system for high-through sample analysis. Show less



Georgia State University

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Researcher

  • Jan 2009 - Jan 2014

   Routine conducts on exact mass and elemental composition determination, tandem mass experiments of GC/MS and/or LC/MS, HPLC separations with UV detector, and sample preparation and purification including liquid-liquid extraction, solid-phase extraction, dialysis, cation exchange, etc.  Maintaining, tuning, calibration, and trouble shoots of Shimadzu GCMS 5050A and HPLC 20A, Waters Micromass® Q-TOF, AB/Sciex API 3200 and Agilent 1200 HPLC.  Provides technical guidance and training to oversight users of the above instruments.  Keeping good records and managements of samples analysis. In additional to the major responsibilities, I also involved in scientific research concerned MS for implementation of research with PI from chemistry or biology department with projects listed below but not limited to:  Accomplished a new analytical method for quantitative detection of inorganic azide ion with LC/MS/MS, published on Chemical Communication and demonstrated on Pittcon 2012.  Synthesized reagents for MALDI image of cancer tissue in corporation with Dr. Chaofeng Dai, published on Chemical Communication and demonstrated on Pittcon 2012.  Optimizing LC/MS/MS method for detecting steroid hormones on protandrous sex change in blue-banded gobies for Dr. Matthew Grober (Assist role).  Synthesis of heterocyclic compounds as potential small molecule inhibitors for protein SecA (Assist role). Show less



 Advanced Alliance Co., Ltd., Beijing, P. R. China

• Scientific information analyst

  • Jul 2007 - Nov 2008

  selection and analysis of the world’s chemical literature for building the CAS databases selection and analysis of the world’s chemical literature for building the CAS databases