Experience

A*STAR - Agency for Science, Technology and Research

• Singapore
• Research Services
• 700 & Above Employee

• Research Fellow

  • Sep 2014 - Present

  Lab of bioimaging probe development (LBPD) have developed a diversity‐oriented fluorescent library approach (DOFLA) which covers covers whole visible light to NIR (400-850nm) range, and demonstrated various cell‐type‐selective chemical probes through unbiased phenotypic screenings.Tumour initiating cells (TICs), also known as cancer stem cells (CSCs) have been implicated in clinical relapse and metastasis of a variety of epithelial cancers. To visualise and isolate TICs in different cancers, TIC-specific universal fluorescent chemical probe, TiY, was developed through DOFLA. At high concentration, TiY showed anti‐TIC activity with low toxicity to non‐TICs. Show less

• Research Fellow

  • Jul 2014 - Present

  LBPD have developed a diversity‐oriented fluorescent library approach (DOFLA) which covers covers whole visible light to NIR (400-850nm) range, and demonstrated various cell‐type‐selective chemical probes through unbiased phenotypic screenings.Tumour initiating cells (TICs), also known as cancer stem cells (CSCs) have been implicated in clinical relapse and metastasis of a variety of epithelial cancers. To visualise and isolate TICs in different cancers, TIC-specific universal fluorescent chemical probe, TiY, was developed through DOFLA. At high concentration, TiY showed anti‐TIC activity with low toxicity to non‐TICs.Work on TiY was published in Angewandte Chemie International Edition [Vol. 57(11) 2851-2854]. Show less



Singapore Bioimaging Consortium (SBIC)

• Biotechnology Research
• 1 - 100 Employee

• Research Fellow

  • Jul 2014 - Present



National University of Singapore

• Research fellow

  • 2013 - Jun 2014