Laurent Bouillaut
VP Discovery and Translational Research at DermBiont, Inc.- Claim this Profile
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Bio
Joseph Sorg
I have had the pleasure of knowing Dr. Laurent Bouillaut for approximately 3 years while I was at Tufts University as a Post-doctoral Associate in Dr. Sonenshein's laboratory. Laurent and I worked closely trying to develop / apply genetic systems for use in Clostridium difficile. His attention to detail and persistence has resulted in several significant contributions to the field of Clostridial biology. Namely, he has shown that a newly-developed drug to combat C. difficile infections reduces the frequency with which C. difficile forms spores and reduces the amount of toxin produced in the presence of the antibiotic. Further, he developed the Mariner transposition system, which was used in a collaborative effort with other Clostridial biologists to study C. perfringens motility. Finally, he elucidated metabolic pathways that show preferential use of proline in the medium for energy generation by C. difficile cells. Since leaving Dr. Sonenshein's laboratory in 2010, to set up my own lab, Laurent has provided to me invaluable advice and recommendations regarding C. difficile genetics and protein purification (e.g. expertise in molecular biology, genetic manipulation of C. difficile and purifying C. difficile proteins expressed in E. coli). His advice and recommendations in these areas has significantly aided my transition to a new investigator. I highly recommend Dr. Bouillaut’s expertise in molecular biology and microbiology. Laurent is detail-oriented, scientifically and professional driven and has a keen eye for experimental nuances.
LinkedIn User
I had the pleasure of collaborating with Laurent on a project that led to two publications. He was always on time and worked diligently to complete his part of the project. He also proved to be very resourceful and was a big help when we were trying to troubleshoot during our experimentations. He is a very pleasant person to work with and if the opportunity comes, I would work with him again.
Joseph Sorg
I have had the pleasure of knowing Dr. Laurent Bouillaut for approximately 3 years while I was at Tufts University as a Post-doctoral Associate in Dr. Sonenshein's laboratory. Laurent and I worked closely trying to develop / apply genetic systems for use in Clostridium difficile. His attention to detail and persistence has resulted in several significant contributions to the field of Clostridial biology. Namely, he has shown that a newly-developed drug to combat C. difficile infections reduces the frequency with which C. difficile forms spores and reduces the amount of toxin produced in the presence of the antibiotic. Further, he developed the Mariner transposition system, which was used in a collaborative effort with other Clostridial biologists to study C. perfringens motility. Finally, he elucidated metabolic pathways that show preferential use of proline in the medium for energy generation by C. difficile cells. Since leaving Dr. Sonenshein's laboratory in 2010, to set up my own lab, Laurent has provided to me invaluable advice and recommendations regarding C. difficile genetics and protein purification (e.g. expertise in molecular biology, genetic manipulation of C. difficile and purifying C. difficile proteins expressed in E. coli). His advice and recommendations in these areas has significantly aided my transition to a new investigator. I highly recommend Dr. Bouillaut’s expertise in molecular biology and microbiology. Laurent is detail-oriented, scientifically and professional driven and has a keen eye for experimental nuances.
LinkedIn User
I had the pleasure of collaborating with Laurent on a project that led to two publications. He was always on time and worked diligently to complete his part of the project. He also proved to be very resourceful and was a big help when we were trying to troubleshoot during our experimentations. He is a very pleasant person to work with and if the opportunity comes, I would work with him again.
Joseph Sorg
I have had the pleasure of knowing Dr. Laurent Bouillaut for approximately 3 years while I was at Tufts University as a Post-doctoral Associate in Dr. Sonenshein's laboratory. Laurent and I worked closely trying to develop / apply genetic systems for use in Clostridium difficile. His attention to detail and persistence has resulted in several significant contributions to the field of Clostridial biology. Namely, he has shown that a newly-developed drug to combat C. difficile infections reduces the frequency with which C. difficile forms spores and reduces the amount of toxin produced in the presence of the antibiotic. Further, he developed the Mariner transposition system, which was used in a collaborative effort with other Clostridial biologists to study C. perfringens motility. Finally, he elucidated metabolic pathways that show preferential use of proline in the medium for energy generation by C. difficile cells. Since leaving Dr. Sonenshein's laboratory in 2010, to set up my own lab, Laurent has provided to me invaluable advice and recommendations regarding C. difficile genetics and protein purification (e.g. expertise in molecular biology, genetic manipulation of C. difficile and purifying C. difficile proteins expressed in E. coli). His advice and recommendations in these areas has significantly aided my transition to a new investigator. I highly recommend Dr. Bouillaut’s expertise in molecular biology and microbiology. Laurent is detail-oriented, scientifically and professional driven and has a keen eye for experimental nuances.
LinkedIn User
I had the pleasure of collaborating with Laurent on a project that led to two publications. He was always on time and worked diligently to complete his part of the project. He also proved to be very resourceful and was a big help when we were trying to troubleshoot during our experimentations. He is a very pleasant person to work with and if the opportunity comes, I would work with him again.
Joseph Sorg
I have had the pleasure of knowing Dr. Laurent Bouillaut for approximately 3 years while I was at Tufts University as a Post-doctoral Associate in Dr. Sonenshein's laboratory. Laurent and I worked closely trying to develop / apply genetic systems for use in Clostridium difficile. His attention to detail and persistence has resulted in several significant contributions to the field of Clostridial biology. Namely, he has shown that a newly-developed drug to combat C. difficile infections reduces the frequency with which C. difficile forms spores and reduces the amount of toxin produced in the presence of the antibiotic. Further, he developed the Mariner transposition system, which was used in a collaborative effort with other Clostridial biologists to study C. perfringens motility. Finally, he elucidated metabolic pathways that show preferential use of proline in the medium for energy generation by C. difficile cells. Since leaving Dr. Sonenshein's laboratory in 2010, to set up my own lab, Laurent has provided to me invaluable advice and recommendations regarding C. difficile genetics and protein purification (e.g. expertise in molecular biology, genetic manipulation of C. difficile and purifying C. difficile proteins expressed in E. coli). His advice and recommendations in these areas has significantly aided my transition to a new investigator. I highly recommend Dr. Bouillaut’s expertise in molecular biology and microbiology. Laurent is detail-oriented, scientifically and professional driven and has a keen eye for experimental nuances.
LinkedIn User
I had the pleasure of collaborating with Laurent on a project that led to two publications. He was always on time and worked diligently to complete his part of the project. He also proved to be very resourceful and was a big help when we were trying to troubleshoot during our experimentations. He is a very pleasant person to work with and if the opportunity comes, I would work with him again.
Experience
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DermBiont, Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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VP Discovery and Translational Research
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Sep 2022 - Present
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Sr. Director of Molecular Biology
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Jan 2022 - Oct 2022
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Biose Industrie
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France
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Pharmaceutical Manufacturing
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100 - 200 Employee
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Project and Business Operation Manager
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Sep 2020 - Jan 2022
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DermBiont, Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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Principal Scientist
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Apr 2019 - Sep 2020
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Pareto Bio, Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Scientist
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Aug 2018 - Feb 2019
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Matrivax
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1 - 100 Employee
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Program Manager
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Apr 2017 - Aug 2018
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Senior Research Scientist
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Oct 2015 - Mar 2017
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Tufts University
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United States
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Higher Education
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700 & Above Employee
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post-doctoral associate
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Apr 2008 - Sep 2015
Regulation of the Stickland reactions in the nosocomial pathogen Clostridium difficile. Identification of a Proline-dependent regulator, PrdR, that controls expression of Stickland genes. Collaborative project with Optimer pharmaceuticals - Effect of Fidaxomicin on gene expression.
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Instructor
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Sep 2013 - Dec 2013
Laboratory modules for Medical School Infectious Disease courses • Guided students during the isolation and identification of bacteria from clinical specimens Small Group instructor for Medical School students
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INRA French National Institute for Agricultural Research
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France
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Research
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700 & Above Employee
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PhD Student
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2004 - 2007
Molecular basis of a quorum sensing system in Bacillus cereus Molecular basis of a quorum sensing system in Bacillus cereus
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La Poste Groupe
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France
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Transportation, Logistics, Supply Chain and Storage
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700 & Above Employee
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Facteur
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1997 - 2004
Facteur pendant vacances scolaires Facteur pendant vacances scolaires
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ACOME
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France
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Appliances, Electrical, and Electronics Manufacturing
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400 - 500 Employee
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Agent de production
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Jun 2001 - Sep 2002
Fiber optic production Fiber optic production
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Education
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2003 - 2007
AgroParisTech - Institut des sciences et industries du vivant et de l'environnement
Doctor of Philosophy (PhD), Microbiology -
2002 - 2003
Université de Caen Basse Normandie
DEA, Medical Microbiology and Bacteriology
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