Quality Assurance (QA) Officer

• Jun 2023 - Present

Support the QA/RA manager in maintaining the company's Quality Management System, creating and updating General Procedures (SOPs) and Work Instructions, performing internal and supplier audits, and writing technical files for certification of In Vitro Diagnostic Medical Devices under the In Vitro Diagnostics Regulation (IVDR, class B-D).

Emergency Response Officer

• Apr 2022 - Present

R&D Technician

• Feb 2022 - Jun 2023

Working on the development of new and improvement of existing Multiplex Real-Time PCR assays based on PathoFinder's proprietary SmartFinder® technology. Current kits can identify upto 24 different pathogens in a single multiplex PCR assay. Supporting the Quality Assurance (QA) department by writing General Procedures, SOPs, and Work Instructions, and by performing internal audits.

Educational Assistant Anatomy

• Jan 2022 - Feb 2022

GGD teststraatmedewerker

• Nov 2021 - Dec 2021

Kitchen Assistant & Server

• Jul 2020 - Nov 2021

ERASMUS+ Master Internship

• Dec 2020 - Jun 2021

Research topic: Highly-defined peptide-phage libraries: A novel approach to deep mutational scanning Research topic: Highly-defined peptide-phage libraries: A novel approach to deep mutational scanning

jobber

• Jun 2016 - Jun 2020

Waiter/kitchenhand at various catering companies, hotels and restaurants. Manage and guide new employees Waiter/kitchenhand at various catering companies, hotels and restaurants. Manage and guide new employees

Junior intern

• Feb 2020 - Apr 2020

Project title: Modified extracellular vesicles rich in HSPB8 modulate autophagy in neuroinflammation. Research group: Neurofunctional Genomics Group, Biomedical Research Institute (BIOMED), Hasselt University Project abstract: Multiple high impact neurodegenerative diseases such as multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease still lack a cure to this day. Build-up of misfolded/damaged protein aggregates is commonly associated with these diseases. Here we explore the potential of heat shock protein beta-8 (HSPB8) loaded extracellular vesicles (EVs) as a cytoprotective factor, able to activate autophagy during neuroinflammation. Co-culture of C20 human microglial cells with EVs harvested from HSPB8 overexpressing human oligodendroglia resulted in modulation of autophagy. We observed a decrease of p62 and an increase of LC3-II protein levels under non inflammatory conditions, suggesting an increase in autophagy. Conversely, LC3-II/LC3-I ratios suggested a decrease in autophagy. Furthermore, under inflammatory conditions, only LC3-II protein levels indicated an autophagy inducing effect, with p62 protein and LC3-II/LC3-I ratios suggesting an autophagy inhibiting effect of the EVs. However, overall, the results are inconclusive due to a small sample size and contradicting measurements. Initial analysis of caspase 1, 3 and 8 protein levels as measures for apoptosis show did not lead to any decisive conclusions. Contradicting results in combination with small sample sizes call for additional research before decisive conclusions can be made on the potential beneficial effect of HSPB8 loaded EVs in neuroinflammation. Show less

Bachelor internship

• Aug 2018 - Jul 2019

Project on the in vivo prediction of carcinogenic compounds using Schmidtea mediterranea stem cell responses with the Zoology: Biodiversity and Toxicology research group at the Centre for Environmental Sciences (CMK), Hasselt University Project on the in vivo prediction of carcinogenic compounds using Schmidtea mediterranea stem cell responses with the Zoology: Biodiversity and Toxicology research group at the Centre for Environmental Sciences (CMK), Hasselt University