Larry Agbor, Ph.D, M.S

Scientific Product Specialist at Danish Myo Technology A/S (DMT)
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Contact Information
Location
Ann Arbor, Michigan, United States, US
Languages
  • French -
  • English -

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John J. Reho, Ph.D.

Larry is a wonderfully motivated and dedicated cardiovascular physiologist with a strong technical prowess in a variety of whole animal, small vessel and advanced molecular biology techniques. The crux of his research program focuses on translational medicine toward an understanding as well as the development of novel approaches to treat human cardiovascular disease. Larry possesses strong leadership skills, an innovative spirit, and possesses a robust platform to critically think, analyze and solve diverse problems. Larry will be an asset to any research team and will significantly contribute to the long term success of his team’s research endeavors.

Pimonrat Ketsawatsomkron

I had a great experience working with Dr. Larry Agbor when I was at University of Iowa, Department of Pharmacology. Larry is a hard-worker and team-oriented scientist. He is always up for challenges and not afraid to take new directions. His studies focus on using molecular biology combined with physiology to understand the mechanism of cardiovascular disease. His wide range of skills in vivo and in vitro will definitely be beneficial for novel discovery.

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Experience

    • Denmark
    • Biotechnology
    • 1 - 100 Employee
    • Scientific Product Specialist
      • Aug 2018 - Present
    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Fellow
      • Oct 2012 - Jul 2018

      Generated and characterized a novel transgenic mouse expressing the hypertension-causing mutant of CUL3 in smooth muscle. Established a methodology for genome editing using cell culture by generating CUL3 knockout and cell lines specifically lacking exon 9 of CUL3. Identified new CUL3 targets in the vasculature that is implicated in vascular dysfunction and hypertension in a mouse model of cardiovascular disease. Develop primary cell culture models including mouse embryonic fibroblast, aortic and mesenteric smooth muscle cells for mechanistic studies. Supervised graduate students and postdoctoral scholars, while improving lab communications Developed strong grant writing skills for extramural funding. Developed strong expertise in gene expression analysis, molecular biology, cellular pharmacology, blood vessel vasoreactivity studies, rodent surgical skills Published research findings in high impact journals. Part of a multidisciplinary laboratory that encompasses work ranging from bioinformatics, physiology, and pharmacogenomics. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Assistant
      • Aug 2007 - Dec 2012

      Characterized a novel molecular mechanism of a transcription factor, the aryl hydrocarbon receptor (AHR) in the regulation of resistance arterial function and blood pressure control using a genetically modified mouse model. Identified a novel role for vascular CYP1A1 in modulating the vasodilatory actions of omega-3 polyunsaturated fatty acids using vascular function and signal transduction studies in a genetically modified mouse model. Developed strong expertise in blood vessel reactivity studies, molecular biology, cellular pharmacology, and rodent surgical skills. Published high quality peer-reviewed articles. Show less

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Associate 3
      • Jun 2006 - Jul 2007

      Developed an innovative surgical technique for arterial blood gas and pH measurement. Enhanced productivity by overseeing the day-to-day running of the laboratory and maintaining SOP. Setup and maintained mouse breeding colony. Supervised graduate and rotating students from the UNM College of Pharmacy. Reviewed the scientific literature and wrote summaries of findings. Developed an innovative surgical technique for arterial blood gas and pH measurement. Enhanced productivity by overseeing the day-to-day running of the laboratory and maintaining SOP. Setup and maintained mouse breeding colony. Supervised graduate and rotating students from the UNM College of Pharmacy. Reviewed the scientific literature and wrote summaries of findings.

    • United States
    • Higher Education
    • 400 - 500 Employee
    • Research Assistant
      • Sep 2004 - May 2006

      Characterized an animal model of male infertility Elucidated gene expression profiling using microarray. Setup laboratory and maintained mouse breeding colonies. Characterized an animal model of male infertility Elucidated gene expression profiling using microarray. Setup laboratory and maintained mouse breeding colonies.

    • United States
    • Market Research
    • 1 - 100 Employee
    • Retail measurement service auditor
      • May 2002 - Aug 2004

Education

  • The University of New Mexico
    Doctor of Philosophy (PhD), Pharmacology and Toxicology
    2007 - 2012
  • New Mexico Highlands University
    Master's degree, Developmental Biology
    2004 - 2006
  • University of Buea
    Bachelor's degree, Biochemistry
    1998 - 2001

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