Laasya Dhandapani
Postdoctoral Researcher at Cima Universidad de Navarra- Claim this Profile
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English Full professional proficiency
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Tamil Native or bilingual proficiency
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Hindi Native or bilingual proficiency
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German Elementary proficiency
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Spanish Professional working proficiency
Topline Score
Bio
Credentials
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ICH GOOD CLINICAL PRACTICE E6 (R2)
The Global Health NetworkSep, 2023- Oct, 2024 -
Clinical Trials Data Management and Quality Assurance
CourseraJun, 2023- Oct, 2024 -
Design and Conduct of Clinical Trials
CourseraApr, 2023- Oct, 2024 -
Foundations of Project Management
CourseraApr, 2023- Oct, 2024 -
Project Management: Healthcare Projects
LinkedInFeb, 2023- Oct, 2024
Experience
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Cima Universidad de Navarra
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Spain
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Research Services
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100 - 200 Employee
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Postdoctoral Researcher
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Mar 2022 - Present
Laboratory of Pediatric Solid Tumors - Design of novel immunotherapy strategies for the treatment of pediatric osteosarcoma - Combination therapies involving oncolytic adenovirus and immune system modulators Laboratory of Pediatric Solid Tumors - Design of novel immunotherapy strategies for the treatment of pediatric osteosarcoma - Combination therapies involving oncolytic adenovirus and immune system modulators
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Centre for Genomic Regulation (CRG)
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Spain
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Biotechnology Research
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200 - 300 Employee
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PhD Student
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Feb 2018 - Jan 2022
Doctoral thesis: Comparative cellular biology of vertebrate primordial oocytes. - Led the work on comparative characterizationof cytoplasmic organization in oocytes of different mammalian species - Established protocols for oocyte isolation and live-imaging to characterize organelle activity - Set up in-vitro tissue culture protocols to study effect of drugs on organelle activity in oocytes - Identified a novel phase-separated compartment consisting of RNA-binding proteins through whole-mount immunofluorescence imaging - Collaborated with different core facilities in the project - Generated and compiled data into a manuscript published in an international peer-reviewed journal Show less
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Technische Universität Dresden
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Germany
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Research
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700 & Above Employee
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Student Assistant (SHK) and Master's thesis
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Jul 2016 - Sep 2017
Master's thesis: The effect of Echovirus-9 on post-transcriptional mechanisms in human pancreatic beta-cell line EndoC βH1. - Worked under the supervision of a senior scientist to study the effect of Echovirus-9 on post transcriptional mechanisms of gene regulation in a human pancreatic beta-cell line EndoC βH1 - Demonstrated re-distribution of an RNA-binding protein in the cell upon viral infection - Identified the cleavage of an RNA binding protein upon viral genome translation in cells and reduction of insulin mRNA levels - Suggested a mechanism by which the virus hijacks a cell's translation machinery and could be implicated in Type I Diabetes - Collaborated with different core facilities as a part of the project - Wrote the master's thesis independently Show less
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Madras Diabetes Research Foundation
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Research
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1 - 100 Employee
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Research Intern
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Jan 2015 - Jul 2015
- Worked under the supervision of a staff scientist to study Hexokinase domain containing 1 (HKDC1) gene variants in gestational Diabetes Mellitus - Isolated DNA from the blood samples of pregnant women obtained from a clinic, controlled for age - Investigated the occurrence of single nucleotide polymorphisms known to affect HKDC1 gene expression by PCR followed by Sanger sequencing - Sample preparation for sequencing to aid in studies of Diabetic Nephropathy - Generated and compiled data, and assisted in manuscript preparation Show less
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CSIR - Central Leather Research Institute
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India
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Research Services
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100 - 200 Employee
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Project Student
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Dec 2013 - Mar 2014
Bachelor's thesis: Biocalorimetric studies of heat based inulinase synthesis. - Worked under the supervision of a scientist to set up different modes of yeast cell-culture in a bioreactor - Optimized media components and nutrient requirements to maximize inulinase enzyme synthesis by the yeast cells - Generated bio-calorimetric data to understand relation between metabolic heat generated and enzyme production in a bioreactor Bachelor's thesis: Biocalorimetric studies of heat based inulinase synthesis. - Worked under the supervision of a scientist to set up different modes of yeast cell-culture in a bioreactor - Optimized media components and nutrient requirements to maximize inulinase enzyme synthesis by the yeast cells - Generated bio-calorimetric data to understand relation between metabolic heat generated and enzyme production in a bioreactor
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Aban India Pvt. Ltd.
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Chennai
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Internship Trainee
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May 2013 - Jun 2013
- Hydrothermal liquefaction of microalgae for biocrude production - Algal cell culture, Bioprocess engineering for biofuel production - Hydrothermal liquefaction of microalgae for biocrude production - Algal cell culture, Bioprocess engineering for biofuel production
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Ramachandra Innovis
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Chennai
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Internship Trainee
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May 2012 - Jun 2012
Instrumentation and practices in Molecular Biology -Hands on training in Molecular Biology and Gene Cloning Techniques -DNA sequencing -Cell culture techniques (bacterial and mammalian) -Cloning and rDNA Technology -Flow Cytometry -Confocal Microscopy Instrumentation and practices in Molecular Biology -Hands on training in Molecular Biology and Gene Cloning Techniques -DNA sequencing -Cell culture techniques (bacterial and mammalian) -Cloning and rDNA Technology -Flow Cytometry -Confocal Microscopy
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Premier Health Centre
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Chennai
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Internship Trainee
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Jun 2011 - Jul 2011
Intern in the Clinical Biochemistry and Hematology Department Assisted laboratory technicians in carrying out blood tests, t3, t4 and tsh tests, and test for malaria Intern in the Clinical Biochemistry and Hematology Department Assisted laboratory technicians in carrying out blood tests, t3, t4 and tsh tests, and test for malaria
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Education
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2018 - 2022
Universitat Pompeu Fabra - UPF
Doctor of Philosophy - PhD, Biomedicine -
2015 - 2017
Technische Universität Dresden
Master’s Degree, Molecular Bioengineering -
2010 - 2014
SRM University
Bachelor's Degree, Biotechnology
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