Kevin Marinus
PHD Candidate at CNCR, Center for Neurogenomics & Cognitive Research- Claim this Profile
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Bio
Experience
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CNCR, Center for Neurogenomics & Cognitive Research
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Netherlands
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Research Services
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1 - 100 Employee
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PHD Candidate
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Sep 2021 - Present
Research group of Ronald van Kesteren (CNCR, MCN). Fundamental research into Alzheimer’s disease using iPSCs. Research group of Ronald van Kesteren (CNCR, MCN). Fundamental research into Alzheimer’s disease using iPSCs.
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CNCR, Center for Neurogenomics & Cognitive Research
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Netherlands
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Research Services
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1 - 100 Employee
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Final Master Research Internship
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Feb 2021 - Jul 2021
Together with Suzanne Miedema and Guus Smit, we assessed whether primary cortical mouse neurons with a progranulin knockdown - a model for frontotemporal dementia with progranulin mutations - exhibit metabolic dysregulations, focusing on genes related to pyruvate metabolism and oxidative phosphorylation. Together with Suzanne Miedema and Guus Smit, we assessed whether primary cortical mouse neurons with a progranulin knockdown - a model for frontotemporal dementia with progranulin mutations - exhibit metabolic dysregulations, focusing on genes related to pyruvate metabolism and oxidative phosphorylation.
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Amsterdam UMC
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Netherlands
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Hospitals and Health Care
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700 & Above Employee
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Master Research Internship (I)
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Feb 2020 - Jul 2020
Grade 8.0. Together with Diede Witkamp and Truus Abbink, we assessed the effects of the ISR-modulating drugs, Guanabenz and Sephin1, on astrocytic neuropathological markers in brain slices from Vanishing White Matter mouse models. Grade 8.0. Together with Diede Witkamp and Truus Abbink, we assessed the effects of the ISR-modulating drugs, Guanabenz and Sephin1, on astrocytic neuropathological markers in brain slices from Vanishing White Matter mouse models.
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CNCR, Center for Neurogenomics & Cognitive Research
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Netherlands
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Research Services
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1 - 100 Employee
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Bachelor Internship
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Feb 2019 - Jun 2019
Grade: 8,5. Together with Ronald van Kesteren, we assessed whether a RanBP1 knockdown is sufficient to mimick several celullar and molecular phenotypes observed in 22q11.2 deletion syndrome patient-derived neurons, using a high-throughput fluorescence microscopy approach. Grade: 8,5. Together with Ronald van Kesteren, we assessed whether a RanBP1 knockdown is sufficient to mimick several celullar and molecular phenotypes observed in 22q11.2 deletion syndrome patient-derived neurons, using a high-throughput fluorescence microscopy approach.
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Education
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Vrije Universiteit Amsterdam
Master of Science - MS, Neurowetenschap (Neurosciences) -
Vrije Universiteit Amsterdam
Bachelor of Science - BS, Biomedische wetenschappen (Biomedical Sciences)