Kelly Trego
Senior Principal Research Scientist at IDEAYA Biosciences- Claim this Profile
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Bio
Experience
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IDEAYA Biosciences
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Principal Research Scientist
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Jan 2023 - Present
South San Francisco, California, United States
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Principal Research Scientist - Protein Sciences, Lead Discovery group
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Apr 2021 - Jan 2023
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Tierra Biosciences
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Scientist, Project leader
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Jul 2019 - Mar 2021
Berkeley, CA • Science lead on internal R&D as well as external projects for customers • Developed proof of concept protein purification method for Tierra's Protein-on-demand production platform • Serve as on-hand consultant for protein purification, and specialized assay development • Lead specialized assay development and protein QC/analytics
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Scientist
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Mar 2017 - Jun 2019
Berkeley, CA • Supervisor of molecular biology core functions, including DNA design, assembly, and product QC • Successful expression and purification of proteins required for cell free DNA expression. • Developed two eukaryotic cell-free systems.
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Research Scientist
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Jun 2014 - Mar 2017
Berkeley, CA • Investigated the human DNA repair protein, XPG, in numerous repair pathways. Patients with functional loss of XPG have a severe developmental disorder, which results in very early death. • Published a novel role for XPG in homologous recombination repair (HRR), probed interactions of XPG with HRR proteins, and investigated the phenotype of cells lacking XPG. • Obtained funding to investigate the role of the loss of XPG, a partner of BRCA1 and BRCA2 in driving genomic instability and… Show more • Investigated the human DNA repair protein, XPG, in numerous repair pathways. Patients with functional loss of XPG have a severe developmental disorder, which results in very early death. • Published a novel role for XPG in homologous recombination repair (HRR), probed interactions of XPG with HRR proteins, and investigated the phenotype of cells lacking XPG. • Obtained funding to investigate the role of the loss of XPG, a partner of BRCA1 and BRCA2 in driving genomic instability and ovarian cancer. Show less
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Project Scientist
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2009 - 2014
Berkeley, CA
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Ruth Kirschstein NRSA Postdoctoral Fellow
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2006 - 2009
• Investigated the significance of the interaction between XPG and the Werner syndrome protein.
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Postdoctoral Researcher
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2003 - 2006
with Dr. John Turchi
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Education
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The Ohio State University
Ph. D., Molecular Genetics -
Miami University
Bachelor of Science (B.S.), Zoology