Experience

Rubius Therapeutics

• United States
• Biotechnology Research
• 1 - 100 Employee

• Analytical Development Analyst

  • Oct 2019 - Aug 2020

  - Contributed to development of a novel red blood cell-based pharmaceutical (injectable biologic) - Optimized and improved a portfolio of assays (ELISA, Cell-based Potency assays (HEK cells)) to assess potency, toxicity and stability of drug product/substance throughout the development pipeline - Generated a wealth of clinical and research data used for IND filing of multiple therapeutic candidates - Developed & debugged functionality of an internal LIMS system - Established an… Show more - Contributed to development of a novel red blood cell-based pharmaceutical (injectable biologic) - Optimized and improved a portfolio of assays (ELISA, Cell-based Potency assays (HEK cells)) to assess potency, toxicity and stability of drug product/substance throughout the development pipeline - Generated a wealth of clinical and research data used for IND filing of multiple therapeutic candidates - Developed & debugged functionality of an internal LIMS system - Established an error detection methodology responsible for capturing hundreds of previously untraceable reporting errors - Became a primary reviewer for all raw data, test methods and reports generated within the Analytical Development Team - Integrated an electronic data capture system for automated assay control trending over time Show less - Contributed to development of a novel red blood cell-based pharmaceutical (injectable biologic) - Optimized and improved a portfolio of assays (ELISA, Cell-based Potency assays (HEK cells)) to assess potency, toxicity and stability of drug product/substance throughout the development pipeline - Generated a wealth of clinical and research data used for IND filing of multiple therapeutic candidates - Developed & debugged functionality of an internal LIMS system - Established an… Show more - Contributed to development of a novel red blood cell-based pharmaceutical (injectable biologic) - Optimized and improved a portfolio of assays (ELISA, Cell-based Potency assays (HEK cells)) to assess potency, toxicity and stability of drug product/substance throughout the development pipeline - Generated a wealth of clinical and research data used for IND filing of multiple therapeutic candidates - Developed & debugged functionality of an internal LIMS system - Established an error detection methodology responsible for capturing hundreds of previously untraceable reporting errors - Became a primary reviewer for all raw data, test methods and reports generated within the Analytical Development Team - Integrated an electronic data capture system for automated assay control trending over time Show less



Affinivax Inc.

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Research Associate

  • Apr 2018 - Oct 2018

  - Contributed to development of multivalent vaccines (Pneumococcal and Nosocomial vaccines) - Responsible for execution of feasibility research, experimentation, documentation and analysis - Developed assays to assess concentration and reaction properties of drug substances (assay platforms included sandwich ELISA, CI-ELISA and MSD) - Collaborated with discovery, production and QC teams to troubleshoot scale-up of vaccine generation and assessment - Wrote and proofread experimental… Show more - Contributed to development of multivalent vaccines (Pneumococcal and Nosocomial vaccines) - Responsible for execution of feasibility research, experimentation, documentation and analysis - Developed assays to assess concentration and reaction properties of drug substances (assay platforms included sandwich ELISA, CI-ELISA and MSD) - Collaborated with discovery, production and QC teams to troubleshoot scale-up of vaccine generation and assessment - Wrote and proofread experimental procedures, protocols and reports - Reported critical data to upper management and external investors for timeline tracking purposes Show less - Contributed to development of multivalent vaccines (Pneumococcal and Nosocomial vaccines) - Responsible for execution of feasibility research, experimentation, documentation and analysis - Developed assays to assess concentration and reaction properties of drug substances (assay platforms included sandwich ELISA, CI-ELISA and MSD) - Collaborated with discovery, production and QC teams to troubleshoot scale-up of vaccine generation and assessment - Wrote and proofread experimental… Show more - Contributed to development of multivalent vaccines (Pneumococcal and Nosocomial vaccines) - Responsible for execution of feasibility research, experimentation, documentation and analysis - Developed assays to assess concentration and reaction properties of drug substances (assay platforms included sandwich ELISA, CI-ELISA and MSD) - Collaborated with discovery, production and QC teams to troubleshoot scale-up of vaccine generation and assessment - Wrote and proofread experimental procedures, protocols and reports - Reported critical data to upper management and external investors for timeline tracking purposes Show less



ALPCO

• United States
• Biotechnology Research
• 1 - 100 Employee

• Associate Scientist, Senior Research Associate

  • 2015 - 2017

  - Contributed to development of clinical and research use chemiluminescent and colorimetric ELISA assays related to various disorders (assays include GLP-1, Glucagon, Calprotectin, IL-6) - Responsible for execution of all research, experimentation, and documentation regarding tests in development - Presented timelines and strategies to upper management to meet deadlines and market requirements - Collaborated with research team and project managers to troubleshoot and optimize customer… Show more - Contributed to development of clinical and research use chemiluminescent and colorimetric ELISA assays related to various disorders (assays include GLP-1, Glucagon, Calprotectin, IL-6) - Responsible for execution of all research, experimentation, and documentation regarding tests in development - Presented timelines and strategies to upper management to meet deadlines and market requirements - Collaborated with research team and project managers to troubleshoot and optimize customer needs - Wrote and proofread experimental procedures, protocols and reports - Generated reports to summarize product evolution through a 5-phase quality system following ISO 13485 and ISO 9001 standards Show less - Contributed to development of clinical and research use chemiluminescent and colorimetric ELISA assays related to various disorders (assays include GLP-1, Glucagon, Calprotectin, IL-6) - Responsible for execution of all research, experimentation, and documentation regarding tests in development - Presented timelines and strategies to upper management to meet deadlines and market requirements - Collaborated with research team and project managers to troubleshoot and optimize customer… Show more - Contributed to development of clinical and research use chemiluminescent and colorimetric ELISA assays related to various disorders (assays include GLP-1, Glucagon, Calprotectin, IL-6) - Responsible for execution of all research, experimentation, and documentation regarding tests in development - Presented timelines and strategies to upper management to meet deadlines and market requirements - Collaborated with research team and project managers to troubleshoot and optimize customer needs - Wrote and proofread experimental procedures, protocols and reports - Generated reports to summarize product evolution through a 5-phase quality system following ISO 13485 and ISO 9001 standards Show less



OPKO Diagnostics, LLC

• United States
• Medical Equipment Manufacturing
• 1 - 100 Employee

• Research Associate II, Research Associate

  • Jul 2012 - Dec 2015

  - Became leading associate in development of the company's flagship, microfluidic assay - Contributed work to multiple clinical diagnostic assay projects including prostate cancer and vitamin D - Performed analytical tests for FDA (510k) acceptance and CE marking in a BL2 lab environment under ISO and GLP/cGMP guidelines - Coordinated clinical FDA testing with on-site and off-site blood donors and staff - Characterized gold nano-particle labelled antibodies using ELISA, SDS-PAGE… Show more - Became leading associate in development of the company's flagship, microfluidic assay - Contributed work to multiple clinical diagnostic assay projects including prostate cancer and vitamin D - Performed analytical tests for FDA (510k) acceptance and CE marking in a BL2 lab environment under ISO and GLP/cGMP guidelines - Coordinated clinical FDA testing with on-site and off-site blood donors and staff - Characterized gold nano-particle labelled antibodies using ELISA, SDS-PAGE, HPLC (SEC and IEX antibody purification and lyophilization analysis), western blotting, and UV-Vis - Independently analyzed data and wrote documentation for standard operating procedures - Compiled and presented data to upper management regarding design review and risk assessment Show less - Became leading associate in development of the company's flagship, microfluidic assay - Contributed work to multiple clinical diagnostic assay projects including prostate cancer and vitamin D - Performed analytical tests for FDA (510k) acceptance and CE marking in a BL2 lab environment under ISO and GLP/cGMP guidelines - Coordinated clinical FDA testing with on-site and off-site blood donors and staff - Characterized gold nano-particle labelled antibodies using ELISA, SDS-PAGE… Show more - Became leading associate in development of the company's flagship, microfluidic assay - Contributed work to multiple clinical diagnostic assay projects including prostate cancer and vitamin D - Performed analytical tests for FDA (510k) acceptance and CE marking in a BL2 lab environment under ISO and GLP/cGMP guidelines - Coordinated clinical FDA testing with on-site and off-site blood donors and staff - Characterized gold nano-particle labelled antibodies using ELISA, SDS-PAGE, HPLC (SEC and IEX antibody purification and lyophilization analysis), western blotting, and UV-Vis - Independently analyzed data and wrote documentation for standard operating procedures - Compiled and presented data to upper management regarding design review and risk assessment Show less



Massachusetts Institute of Technology

• United States
• Higher Education
• 700 & Above Employee

• Research Assistant

  • Jan 2012 - May 2012

  -Assisted in genetic development of bi-specific antibodies via PCR and mammalian phage display in CHO cells -Conducted ELISA and Cell-Based assaying of antibodies -Analyzed tissue growth patterns using microscopy and hematological techniques -Assisted in baculovirus transfection and oncological research projects -Optimized Dengue virus growth conditions and maintained incubators for various cancer cell lines -Assisted in genetic development of bi-specific antibodies via PCR and mammalian phage display in CHO cells -Conducted ELISA and Cell-Based assaying of antibodies -Analyzed tissue growth patterns using microscopy and hematological techniques -Assisted in baculovirus transfection and oncological research projects -Optimized Dengue virus growth conditions and maintained incubators for various cancer cell lines