Director of Quality Control

• Feb 2023 - Present

Director of Quality Control

• Sep 2020 - Feb 2023

Associate Director

• Jun 2019 - Sep 2020

• Lead the technical team to provide technical expertise and guidance to the quality organization by supporting or managing deviations, investigations, changes, risk assessments and CAPAs.• Develop and support deployment of quality requirements for technologies and/or modalities which require intensive analytical methodology and technical acumen• Lead the technical team in the design and execution of technical studies, method qualification and validation • Provide leadership and guidance in incoming method transfers from analytical development and outgoing method transfer to QC commercial or external business partners • Establish data analytics to serve as metrics, control charts and trending Show less

Senior Scientist

• Jul 2016 - May 2019

Kite - A Gilead Company• Authored the development and validation section of the BLA CMC section for Yescarta (Axi-Cel/KTE-C19).• Developed, qualified and validated a multiplex qPCR method in a few months for the detection of microbiological contamination (RCR/RCL/mycoplasma) in products that offers significant cost savings to the company.• Served as SME in PLI and answered inspector/agency questions• A major contributor to the set-up and establishment of the qPCR/PCR GMP facilities.• Oversaw and managed QC assay technology transfer to Fosun Kite Bio, China and Daiichi Sankyo, Japan Technical skills: Multicolor Flow cytometry BD Canto II, BD FACSDiva software, Immunoassay (ELISA), multiplex qPCR, qPCR Show less

Scientist

• Apr 2015 - Jun 2016

Postdoctoral Scientist in the Laboratory of Prof. John J. Rossi

• Jun 2011 - Apr 2015

Mentor: Prof. John J. Rossi, endowed Chair Professor, dean of city of hope graduate school, cofounder of Dicerna Pharmaceuticals (NASDAQ: DRNA) Accomplishments: • Published three lead authored papers in peer-reviewed journals and four first-authored book chapters • Invited to author a laboratory protocol text book in siRNA delivery • Invited to give lectures at Annual meeting of Americal Society of Gene and Cell Therapy and 2013 International Conference on RNA nanotechnology and therapeutics • Served as a panelist for National Science foundation (NSF) • Served as a reviewer for national grant agencies and a number of prestigious journals, including Nature Medicine, PLOS one....etc Technical skills: SPR, ITC, DSC, light scattering, protein purification, SELEX, siRNA design, luciferase assay, flow cytometry, confocal microscopy and oligonucleotide chemistry Show less

President

• Mar 2013 - Aug 2014

OBR’s mission is to engage our academic and industry communities on-campus to foster a conversation about the health care and life sciences industry. OBR expanded from Oxford across the UK, and to America, Singapore and Hong Kong - and now to over 25,000 members, and partnerships with the world's leading life science and consulting companies, such as Roche, GSK and McKinsey & Co. Responsibilities: • Directed and managed the Los Angeles leadership team of Oxbridge Biotech Roundtable (OBR) to organize events. • Recruited and motivated a talented team towards common goals. • Engaged both academics and industry professionals to move scientific ideas forward through the biggest life science business plan competition OneStart, sponsored by SR One. • Forged partnership and raised funding from Morrison & Foerster LLC, TriLink Biotechnology Inc, University of Southern California and Keck Graduate Institute for chapter operation. Show less

Senior Resident tutor | Resident Tutor | Honorary Resident Tutor

• Dec 2006 - May 2011

Responsibilities:• Maintained a good order in the student hostel• created and maintained conditions conducive to intellectual, social, and cultural development of all residents• Managed the general administration of the student hostel with 300 residents • Maintained the moral, social and general well-being of all residents.• Organized activities for all residents and/or other graduate students

Graduate Researcher in the Laboratory of Dr. Julian A. Tanner

• Sep 2006 - Jun 2010

The University of Hong Kong, founded in 1911, is the oldest tertiary institution in Hong Kong. The University of Hong Kong was ranked 24th amongst the top 200 universities globally by the Times Higher Education - Quacquarelli Symonds (THE-QS) World University Rankings.Accomplishments:• Published three first-authored and one co-authored research paper in peer-reviewed journals, one review paper on Chemical Biology, one approved patent• Identified effective aptamers for osteoporosis that rivals Amgen’s phase 3 biologics Romosozumb®. Show less

Visiting Research Scientist in the Laboratory of Prof. Petri M. Pihko

• Jan 2005 - Jul 2005

Helsinki University of Technology is the second-oldest university in Finland, and is committed to the provision of high-quality education. HUT is surrounded by the active business zone, which is home to headquarters of several significant companies like Nokia, Kone and Neste Oil, as well as to providers of various support services for businesses, start-ups and new companies. Responsibilities: Research on the effect of additives on the proline-catalyzed ketone-aldehyde aldol reactions. Accomplishments: • My work was acknowledged in Pihko, P.M. et al (2006) Effect of Additives on the Proline-Catalyzed Ketone—Aldehyde Aldol Reactions. Organic Chemistry. 37:21 23 May 2006. DOI:10.1002/chin.200621027 Show less

Undergraduate Research Assistant in the Laboratory of Dr. Jiandong Huang

• Jun 2004 - Sep 2004

Accomplishments • First global laboratory to characterize Severe Associated Respiratory (SARS) Virus helicase a few weeks after the global outbreak in 2004 • Identified and characterized bananin and bismuth based small molecule inhibitors against SCV helicase for SARS therapy. • Provided technical support to graduate students and postdoctoral fellows creating recombinant SARS helicase proteins and SCV cDNA genome. • Developed a non-radioactive Malachite green phosphate release assay to detect ATPase activity of SCV helicase • Developed a non-radioactive FRET-based assay to detect nucleic acid unwinding activity of SCV helicase • One research paper in Angew. Chem. Int. Ed Engl. Show less