Karolina Mizeracka

Senior Scientist at Foghorn Therapeutics Inc.
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Contact Information
us****@****om
(386) 825-5501
Location
Newton Centre, Massachusetts, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 100 - 200 Employee
    • Senior Scientist
      • Jul 2022 - Present

      Targeted Degradation Platform Targeted Degradation Platform

    • Postdoctoral Research Fellow
      • Aug 2012 - Jul 2022

      Utilized single-cell datasets to generate a number of new in vivo reporters for genetically inaccessible glial cell types in C. elegans Discovered new genes that are required for glial cell development and function through genome-wide, unbiased mutagenesis screens Developed assays for the execution of a high-throughput, whole organismal drug-screening platform for the human neurological disorder Kabuki syndrome modeled in C. elegans Utilized single-cell datasets to generate a number of new in vivo reporters for genetically inaccessible glial cell types in C. elegans Discovered new genes that are required for glial cell development and function through genome-wide, unbiased mutagenesis screens Developed assays for the execution of a high-throughput, whole organismal drug-screening platform for the human neurological disorder Kabuki syndrome modeled in C. elegans

    • United Kingdom
    • Education Administration Programs
    • 100 - 200 Employee
    • Adjunct Faculty
      • Jan 2021 - May 2021

      Instructor of record for Introduction to Genomics course Instructor of record for Introduction to Genomics course

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Student
      • Aug 2006 - Aug 2012

      Discovered a new role for Notch signaling in the establishment of cell identity after exit from progenitor state in the vertebrate retina Performed single-cell profiling experiments of wild-type and Notch1- mutant retinal cells to determine novel targets downstream of Notch signaling Identified functional roles for new Notch1 downstream target genes through in vivo misexpression and RNAi assays Discovered a new role for Notch signaling in the establishment of cell identity after exit from progenitor state in the vertebrate retina Performed single-cell profiling experiments of wild-type and Notch1- mutant retinal cells to determine novel targets downstream of Notch signaling Identified functional roles for new Notch1 downstream target genes through in vivo misexpression and RNAi assays

Education

  • Harvard Medical School
    Doctor of Philosophy - PhD, Genetics
    2005 - 2012
  • Tufts University
    Bachelor of Science - BS, Biochemistry
    2002 - 2005

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