José Britto-Júnior
Postdoctoral Researcher at Faculdade de Ciências Médicas da Unicamp- Claim this Profile
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Bio
Experience
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Faculdade de Ciências Médicas da Unicamp
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Brazil
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Research Services
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200 - 300 Employee
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Postdoctoral Researcher
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Jan 2023 - Present
6-Nitrodopamine (6-ND) has several actions on the cardiovascular system. It is a potent vasodilator, acting through antagonism of D2-like dopaminergic receptors, and one hundred times more potent than noradrenaline and adrenaline and ten thousand times more potent than dopamine as a chronotropic agent in the isolated atrium of Rattus norvegicus. It has a contractile effect on vas deferens of Rattus norvegicus and humans, and this effect is through its interaction with a specific receptor for 6-ND, which is blocked by tricyclic antidepressants, adrenergic antagonists and b-adrenergic antagonists. At the moment, we do not know if this action of 6-ND is due to itself, or to a possible metabolism of the same in 6-nitronoradrenaline (6-NN) and 6-nitroadrenaline (6-NA). Show less
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Faculdade de Ciências Médicas da Unicamp
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Brazil
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Research Services
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200 - 300 Employee
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PhD
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Apr 2019 - Nov 2022
Evaluation of human umbilical cord vessels as a source of endothelium-produced catecholamines. Description: The objective of this work is to investigate the physiological role of catecholamines produced by the human umbilical cord endothelium. Human umbilical cord vessels (veins and arteries) will be used in electric field stimulus-induced contraction (EFS) in the presence and absence of adrenergic antagonists. Contraction by EFS will also be performed in vascular rings with and without endothelium. The location of TH in vessel endothelium will be investigated by mass spectrometer-coupled liquid chromatography (LC-MS / MS), immunohistochemistry and in situ hybridization. Situation: In progress; Nature: Research. Show less
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AG COMÉRCIOS DE PRODUTOS FARMACEUTICOS LTDA
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Goiânia e Região, Brasil
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Pharmaceutical Sales Manager
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Feb 2017 - Apr 2019
Experience Pharmacovigilance Analyst; Electronic bidding; Customer service; Responsible for sales management; Inventory management; Business strategy planning manager; Employee training; Technical manager; Pharmaceutical care; Knowledge of pharmaceutical routines; Experience in team management; Interpersonal Relationship Ability; Ability for negotiation, decision and logical reasoning; focus on process and results; ease in performing analytical work, proactivity and organization; good communication and verbal fluency. Report writing, advisor, monitoring; planning and implementation of motivational actions. • Knowledge in JDEdwards, E-sales, Microsoft Outlook, SNGPC and SEMC. • Recruit and schedule clinical research volunteers. Acting with filling out the clinical form and applying the Informed Consent Form (ICF). • Knowledge of materials and medicines, the fulfillment of medical and nursing requests and prescriptions, perform tasks of control and maintenance of pharmaceutical products; team organization, dispensing medicines and materials from the pharmacy. Identify and store medicines Prescription analysis and psychotropic control Show less
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Universidade Federal de Goiás
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Brazil
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Higher Education
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700 & Above Employee
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Master's degree
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Apr 2016 - Apr 2018
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Education
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Universidade Estadual de Campinas
Doctor of Philosophy - PhD, Endothelium-derived dopamine modulates EFS-induced contraction of human umbilical vessels -
Universidade Federal de Goiás
Master's degree, Cardiovascular Physiology and Pharmacology, nitric oxide, oxidative stress, antioxidant. -
FAC UNICAMPS - Faculdade Unida de Campinas
Graduaçao, Farmácia