Jonah Simon
Senior Scientist at Axial Therapeutics, Inc.- Claim this Profile
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Bio
Experience
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Axial Therapeutics, Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Scientist
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Jul 2022 - Aug 2023
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Scientist
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Jun 2021 - Jul 2022
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Research Associate II
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Dec 2018 - Jun 2021
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Research Associate
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Jul 2017 - Oct 2018
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The Discovery Engine
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Spain
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Technology, Information and Internet
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1 - 100 Employee
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Volunteer
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Jan 2017 - Jul 2017
• Assist with conceptual product development and direction • Assist with practical tasks to spread DiscoveryEngine • Developed a plan to grow a loyal user base • Assist with conceptual product development and direction • Assist with practical tasks to spread DiscoveryEngine • Developed a plan to grow a loyal user base
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Research Assistant
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Nov 2014 - Jun 2017
• Created a novel single-copy ALS model in C. elegans using CRISPR/Cas9 genome editing • Elucidated a molecular pathway connecting miRNA dysfunction to neuromuscular junction defects in a SMA model • Evaluated phenotypes of single-copy ALS models with a variety of behavioral, biochemical, and pharmacological assays • Created a novel single-copy ALS model in C. elegans using CRISPR/Cas9 genome editing • Elucidated a molecular pathway connecting miRNA dysfunction to neuromuscular junction defects in a SMA model • Evaluated phenotypes of single-copy ALS models with a variety of behavioral, biochemical, and pharmacological assays
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SENS Research Foundation
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United States
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Research Services
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1 - 100 Employee
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Oncology Intern
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May 2015 - Aug 2015
• Developed and validated a high-throughput imaging assay to quantify Alternative Lengthening of Telomeres activity based on a novel biomarker • Developed and optimized a protocol combining immunofluorescence and fluorescent in situ hybridization to detect protein-nucleotide interactions at telomeres • Developed and validated a high-throughput imaging assay to quantify Alternative Lengthening of Telomeres activity based on a novel biomarker • Developed and optimized a protocol combining immunofluorescence and fluorescent in situ hybridization to detect protein-nucleotide interactions at telomeres
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Biogen
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South Africa
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Wellness and Fitness Services
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1 - 100 Employee
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Neurology Intern
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May 2014 - Aug 2014
• Optimized a high-content immunofluorescence assay to quantify stress granule dynamics in human cell lines • Characterized stress granule dynamics in response to a variety of cellular stresses and developed protocols for robust stress granule induction • Contributed to an exploratory project in target discovery • Optimized a high-content immunofluorescence assay to quantify stress granule dynamics in human cell lines • Characterized stress granule dynamics in response to a variety of cellular stresses and developed protocols for robust stress granule induction • Contributed to an exploratory project in target discovery
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Research Assistant
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Nov 2012 - Jun 2013
• Cloned a gene for a voltage gated sodium channel subtype in P. terribilis • Identified mutation likely conferring batrachotoxin resistance • Cloned a gene for a voltage gated sodium channel subtype in P. terribilis • Identified mutation likely conferring batrachotoxin resistance
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The Daily Catch
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Singapore
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Fisheries
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1 - 100 Employee
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Food Runner; Busboy
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Jun 2010 - Aug 2012
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Education
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Brown University
Bachelor of Science - BS, Neuroscience -
Cambridge Rindge and Latin School
High School Diploma