John Liddon
Associate Principal Scientist Level II at Pharmaron- Claim this Profile
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Bio
Experience
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Pharmaron
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China
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Pharmaceutical Manufacturing
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700 & Above Employee
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Associate Principal Scientist Level II
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Jan 2018 - Present
Enthusiastic Associate Principal Scientist currently working in the CRO/CDMO industry. I am a synthetic organic chemist by trade. *Project manager in charge of multi kg scale GMP/GLP drug substance deliveries. *Team leader/ people manager. Able to manage the interface between process chemistry, analytical chemistry, materials science, and quality assurance. *Strong track record of solving complex chemistry problems and delivering projects on time and within budget. *Active member of the process safety team. Experience in assembling and reviewing process safety reports. Part of the departmental specialist group responsible for process safety, including approval of process safety assessment reports (PSARs) prior to plant execution. Knowledge of process safety techniques (DSC. RC1. RSD. ARC). *Skilled in process chemistry scale up, plant operations, and tech transfer. *Regularly assembling and reviewing batch documents. Part of a select group of experienced process chemists responsible for reviewing and pre-authorising batch records before plant execution. *Novel contributions to route design have featured on client patents. *Client facing/ public speaking. Clear data presentation delivered with confidence and conclusions drawn. *Experienced in operating within a GMP framework. Knowledge of ICH guidelines. *Always looking for new challenges and opportunities. Show less
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University of York
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United Kingdom
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Higher Education
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700 & Above Employee
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Postdoctoral Research Associate in Synthetic Organic Chemistry
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May 2015 - Dec 2017
For my postdoctoral studies, I moved to the University of York to work on the synthesis of small molecule spirocycles in collaboration with Prof. Richard Taylor and Dr Will Unsworth. Aside from day to day lab-based research and collaborative project input, I helped edit submitted Tetrahedron journals for Elsevier and also organised problem sessions for PhD and Postdoctoral researchers on a weekly basis. I also became part of the Elsevier Advisory Panel. York offered many opportunities to practice public speaking and engaging with both the scientific and non-scientific community. In 2017 I was selected to attend STEM for Britain in Parliament to present my research to a lay audience, and also made it through to the final round of the SCI Retrosynthesis Competition at the SCI headquarters in London. While at York I chaired plenary sessions, introduced visiting academics in front of medium-sized audiences, and attended many conferences and courses including the BOSS symposium (In Antwerp) and the Medicinal Chemistry Resident School (in Loughborough). At the end of my contract, I made the move from academia to industry by getting a position at Pharmaron UK. For selected publications see; J. T. R. Liddon et al, Org. Lett., 2018, 20 (11), 3349-3353, J. T. R. Liddon et al, Org. Lett., 2016, 18 (24), 6328-6331 and J. T. R. Liddon et al, Chem. Eur. J., 2016, 22, 8777-8780. For my ORCID profile see; orcid.org/0000-0002-5287-9817 Show less
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University of Oxford
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United Kingdom
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Research Services
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700 & Above Employee
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Sep 2011 - May 2015
Following my MChem, I moved to Oxford to undertake my DPhil working with Prof. Jeremy Robertson. My DPhil work required many multi-step syntheses on milligram to multi-gram scale, using a wide variety of techniques and transformations. Separation, purification, and identification of complex reaction mixtures by chromatography was a routine occurrence and lent to mechanistic understanding of novel reactions. During this time I developed skills in presenting to small–medium sized audiences, collaborative teamworking, and detailed record keeping.As part of my DPhil, I spent three months on placement at Eli Lilly (Erl Wood) working in an industrial environment.My PhD work resulted in the publication J. Org. Chem. 2019, 84 (21), 13780-13793. Show less
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Oct 2014 - Dec 2014
In the final year of my DPhil, I spent several months demonstrating fundamental laboratory skills for 1st year undergraduate students.
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Eli Lilly and Company
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Visiting PhD Student
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Mar 2013 - Jun 2013
As part of my CASE award funding during my DPhil, I spent three months at Eli Lilly (Erl Wood site) continuing my studies in a professional pharmaceutical environment. I received first-hand experience of what is expected at a professional research level, including the high safety, GLP, and record keeping standards set by these companies. As part of my CASE award funding during my DPhil, I spent three months at Eli Lilly (Erl Wood site) continuing my studies in a professional pharmaceutical environment. I received first-hand experience of what is expected at a professional research level, including the high safety, GLP, and record keeping standards set by these companies.
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AstraZeneca
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United Kingdom
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Pharmaceutical Manufacturing
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700 & Above Employee
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Visiting Placement Student
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Sep 2008 - Aug 2009
For my Diploma in Industrial Studies during my MChem, I spent one year working at AstraZeneca (Charnwood site) in the process research and development department. My work at Charnwood culminated in co-authorship on a publication: Development of an Extremely Efficient Oxidative Chlorination Reaction: The Value of Routine Data Collection. N. Barnwell, P. Cornwall, D. Horner, J. Knott, J. Liddon. Org. Process Res. Dev. 2010, 14, 278–288. For my Diploma in Industrial Studies during my MChem, I spent one year working at AstraZeneca (Charnwood site) in the process research and development department. My work at Charnwood culminated in co-authorship on a publication: Development of an Extremely Efficient Oxidative Chlorination Reaction: The Value of Routine Data Collection. N. Barnwell, P. Cornwall, D. Horner, J. Knott, J. Liddon. Org. Process Res. Dev. 2010, 14, 278–288.
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Education
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University of Oxford
Doctor of Philosophy (Ph.D.), Organic Chemistry -
Loughborough University
Master’s Degree, Chemistry -
Benjamin Britten High School
High School