John F. Thompson
Principal Application Scientist at Nabsys- Claim this Profile
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Bio
Experience
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Nabsys
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United States
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Biotechnology Research
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1 - 100 Employee
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Principal Application Scientist
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Jun 2023 - 7 months
Providence, Rhode Island, United States
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Consultant
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Mar 2023 - 10 months
Genomics, Gene Therapy, Diagnostics, Drug Development
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Homology Medicines, Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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VP of Genomics and Computational Biology
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Mar 2020 - Mar 2023
Characterize and develop AAV-based gene therapies Write/review IND and related FDA-required documents
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Head of Research and Early Development
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Mar 2019 - Mar 2020
Baltimore, Maryland Area Develop NGS-based assays for detection of somatic cancer-related variants Write/review 510k-related documents for FDA-approval of kitted assays
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Principal Scientist II
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Jan 2018 - Mar 2019
Baltimore, Maryland Area
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Chief Technology Officer
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Apr 2014 - Dec 2017
Cambridge, MA Develop/improve genetic assays for diagnosing rare pediatric diseases Illumina and Ion Torrent-based exome sequencing assays for rare pediatric genetic diseases
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Nabsys
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Director, Applications and External Collaborations
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Aug 2011 - Mar 2014
Providence, Rhode Island Area Responsible for: • Improving protocols for mapping and sequencing of very long DNAs (>100kb) in nanodetector analysis • Developing new applications for answering a broad range of genomic questions
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Helicos Biosciences Corporation
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Director, Genomic Research
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Dec 2007 - Aug 2011
• Design and validate clinical diagnostic assays for genetic testing, coordinate implementation • Develop novel applications and methods for ultra high-throughput single molecule sequencing • Coordinate internal and external resources to maximize impact of technology • Seek and administer NIH and other grant funding
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Pfizer
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Senior Research Fellow
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Jun 1988 - Dec 2007
• Varied roles in pharmacogenomics, whole genome scans, molecular biology, supervision of biotechnology collaborations • Worked with Lipitor commercial team for genetic analysis of statin response, lead author in publications • Major role in initiation and implementation of GAIN consortium for whole genome scans, pioneering effort with NIH, FNIH, Perlegen, Affymetrix, & Broad Institute • Designed and implemented first and subsequent whole genome scans at Pfizer • Proposed and… Show more • Varied roles in pharmacogenomics, whole genome scans, molecular biology, supervision of biotechnology collaborations • Worked with Lipitor commercial team for genetic analysis of statin response, lead author in publications • Major role in initiation and implementation of GAIN consortium for whole genome scans, pioneering effort with NIH, FNIH, Perlegen, Affymetrix, & Broad Institute • Designed and implemented first and subsequent whole genome scans at Pfizer • Proposed and designed experiments to test CETP genetic variants with torcetrapib, worked with early and full development teams on all aspects of genetics • Led team that analyzed genetic variants associated with serious adverse event (TdP) in dofetilide-treated patients, senior author on publications Show less
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Research Assistant Professor
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Jun 1982 - Jun 1988
• DNA-protein interactions in bacterial and viral systems • Identified novel host factor involved in site specific recombination • Developed highly cited method for analysis of DNA bending • Supervised graduate students/technicians
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Education
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University of California, Berkeley
Doctor of Philosophy - PhD, Chemistry -
University of California, Berkeley
PhD, Biophysical Chemistry -
Yale University
BS, Chemistry -
Yale University
Bachelor of Science - BS, Chemistry