John F. Thompson

Principal Application Scientist at Nabsys
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Contact Information
us****@****om
(386) 825-5501
Location
Providence, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Principal Application Scientist
      • Jun 2023 - 7 months

      Providence, Rhode Island, United States

    • Consultant
      • Mar 2023 - 10 months

      Genomics, Gene Therapy, Diagnostics, Drug Development

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • VP of Genomics and Computational Biology
      • Mar 2020 - Mar 2023

      Characterize and develop AAV-based gene therapies Write/review IND and related FDA-required documents

    • Head of Research and Early Development
      • Mar 2019 - Mar 2020

      Baltimore, Maryland Area Develop NGS-based assays for detection of somatic cancer-related variants Write/review 510k-related documents for FDA-approval of kitted assays

    • Principal Scientist II
      • Jan 2018 - Mar 2019

      Baltimore, Maryland Area

    • Chief Technology Officer
      • Apr 2014 - Dec 2017

      Cambridge, MA Develop/improve genetic assays for diagnosing rare pediatric diseases Illumina and Ion Torrent-based exome sequencing assays for rare pediatric genetic diseases

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Director, Applications and External Collaborations
      • Aug 2011 - Mar 2014

      Providence, Rhode Island Area Responsible for: • Improving protocols for mapping and sequencing of very long DNAs (>100kb) in nanodetector analysis • Developing new applications for answering a broad range of genomic questions

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Director, Genomic Research
      • Dec 2007 - Aug 2011

      • Design and validate clinical diagnostic assays for genetic testing, coordinate implementation • Develop novel applications and methods for ultra high-throughput single molecule sequencing • Coordinate internal and external resources to maximize impact of technology • Seek and administer NIH and other grant funding

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Senior Research Fellow
      • Jun 1988 - Dec 2007

      • Varied roles in pharmacogenomics, whole genome scans, molecular biology, supervision of biotechnology collaborations • Worked with Lipitor commercial team for genetic analysis of statin response, lead author in publications • Major role in initiation and implementation of GAIN consortium for whole genome scans, pioneering effort with NIH, FNIH, Perlegen, Affymetrix, & Broad Institute • Designed and implemented first and subsequent whole genome scans at Pfizer • Proposed and… Show more • Varied roles in pharmacogenomics, whole genome scans, molecular biology, supervision of biotechnology collaborations • Worked with Lipitor commercial team for genetic analysis of statin response, lead author in publications • Major role in initiation and implementation of GAIN consortium for whole genome scans, pioneering effort with NIH, FNIH, Perlegen, Affymetrix, & Broad Institute • Designed and implemented first and subsequent whole genome scans at Pfizer • Proposed and designed experiments to test CETP genetic variants with torcetrapib, worked with early and full development teams on all aspects of genetics • Led team that analyzed genetic variants associated with serious adverse event (TdP) in dofetilide-treated patients, senior author on publications Show less

    • Research Assistant Professor
      • Jun 1982 - Jun 1988

      • DNA-protein interactions in bacterial and viral systems • Identified novel host factor involved in site specific recombination • Developed highly cited method for analysis of DNA bending • Supervised graduate students/technicians

Education

  • University of California, Berkeley
    Doctor of Philosophy - PhD, Chemistry
  • University of California, Berkeley
    PhD, Biophysical Chemistry
    1978 - 1982
  • Yale University
    BS, Chemistry
    1975 - 1978
  • Yale University
    Bachelor of Science - BS, Chemistry

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