Joem Serrano

Senior Research Scientist at Kite Pharma
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United States, US

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Experience

    • United States
    • Biotechnology Research
    • 700 & Above Employee
    • Senior Research Scientist
      • Feb 2023 - Present

    • Research Scientist
      • Nov 2021 - Feb 2023

    • United States
    • Medical Equipment Manufacturing
    • 700 & Above Employee
    • Quality Assurance Scientist
      • Apr 2021 - Nov 2021

      Miami, Florida, United States • Review and revise specifications and test methods used within the hematology laboratory to improve accuracy, precision and efficiency within the laboratory. • Perform data review of quality control tests to ensure product specifications are met. • Support process and product non-conformances in line with OpCo and departmental Standard Operating Procedures. • Perform Risk Assessments, FMEA. • Support and lead Kaizen events.

    • United States
    • Biotechnology Research
    • 700 & Above Employee
    • SR. QC Associate
      • Jun 2018 - Apr 2021

      Oceanside, California Perform tests to detect adventitious agents in cell culture fluids. Test lot release samples, cell banks, pre-banks and validation samples. Manage change control records. Manage DMS records. Compliance support: as auditor, liaison, and subject expert matter (SME) Sample handling management owner (Labware LIMS management) and assay owner in the Adventitious Agent group in Oceanside QC. Culture multiple cell lines to support bioassays, and other QC processes. Led a team of… Show more Perform tests to detect adventitious agents in cell culture fluids. Test lot release samples, cell banks, pre-banks and validation samples. Manage change control records. Manage DMS records. Compliance support: as auditor, liaison, and subject expert matter (SME) Sample handling management owner (Labware LIMS management) and assay owner in the Adventitious Agent group in Oceanside QC. Culture multiple cell lines to support bioassays, and other QC processes. Led a team of QC associates. Support Roche Critical Reagent Management (CRIM) group. QC trainer. Led different collaboration projects to transfer new cell lines from the Biological Techniques (BT) group in SSF to the Global Biologic cell culture group. Participate in method transfers. Led multiple projects to improve QC processes

    • QC Associate
      • Apr 2015 - Jun 2018

      Oceanside, California, United States

    • QC Specialist
      • Jun 2013 - Apr 2015

      San Francisco Bay Area

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Associate Immunologist
      • Mar 2011 - Jun 2013

      Baltimore, Maryland Area • Perform cell-based assays in compliance with cGMP. • Develop new bioassays. • Train coworkers. • Write SOPs, Standard Specifications, IQ/OQ/PQ and other cGMP documents.

    • United States
    • Hospitals and Health Care
    • 1 - 100 Employee
    • Research Technologist (Associate)
      • Sep 2009 - Apr 2011

      Baltimore, Maryland Area • Implemented a new platform (using cell-based assays and molecular biology tools) for screening and studying neuroprotective drugs. • Designed, cloned and produced plasmids (expressing fusion proteins) that are specifically expressed in neuronal cells. • Isolated and worked with neuronal primary cell culture. • Transfected primary cells. • Performed immunohistochemistry studies to support drug screanning. • Studied the mechanisms of action of various drugs that exhibit… Show more • Implemented a new platform (using cell-based assays and molecular biology tools) for screening and studying neuroprotective drugs. • Designed, cloned and produced plasmids (expressing fusion proteins) that are specifically expressed in neuronal cells. • Isolated and worked with neuronal primary cell culture. • Transfected primary cells. • Performed immunohistochemistry studies to support drug screanning. • Studied the mechanisms of action of various drugs that exhibit neuroprotective properties in HIV-dementia. • Produced and purified several variants of the recombinant protein Tat. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Associate
      • Oct 2008 - Aug 2009

      Miami/Fort Lauderdale Area •Studied the mechanisms of action of an orally active plant extract (BIRM) that exhibits antitumor properties. •Made important contributions that suggest that BIRM interferes in the Epithelial Mesenchymal Transition that undergoes in prostate tumors. •Managed the laboratory. •Supported actively the principal investigator and post docs in different projects.

    • Thailand
    • Research Services
    • 1 - 100 Employee
    • Junior Investigator, Research Associate
      • 2003 - 2006

      •Studied the mechanisms of action of a novel proapoptotic peptide called CIGB300 that exhibits anticancer properties. •Contributed to demonstrate the antitumor effect of CIGB300 in different animal models: direct and systemic administration of the drug in murine syngenic tumors and human tumors xenografted in nude mice. •Analyzed and validated data from proteomic studies of CIGB300. •Demonstrated the antitumor effect of different drugs and natural products on a large panel of cell… Show more •Studied the mechanisms of action of a novel proapoptotic peptide called CIGB300 that exhibits anticancer properties. •Contributed to demonstrate the antitumor effect of CIGB300 in different animal models: direct and systemic administration of the drug in murine syngenic tumors and human tumors xenografted in nude mice. •Analyzed and validated data from proteomic studies of CIGB300. •Demonstrated the antitumor effect of different drugs and natural products on a large panel of cell lines. •Characterized the effect of drugs derived from CIGB300. •Produced and purified different recombinant proteins. •Characterized a monoclonal antibody that recognizes an antigen overexpressed in colon tumors Show less

Education

  • The Johns Hopkins University
    Master, Biotechnology
    2010 - 2012
  • University of Havana
    Bachelor, Biology
    1998 - 2003

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