Joanne Lau

Postdoctoral Researcher at Caltech
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Contact Information
us****@****om
(386) 825-5501
Location
Pasadena, California, United States, US
Languages
  • English Full professional proficiency
  • Malay Professional working proficiency
  • Chinese Limited working proficiency

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Experience

    • United States
    • Research Services
    • 700 & Above Employee
    • Postdoctoral Researcher
      • Jan 2017 - Present

    • United States
    • Higher Education
    • 700 & Above Employee
    • PhD Candidate, Microbiology
      • May 2010 - May 2016

      Undertook research aimed at understanding the molecular mechanisms of protein degradation during bacterial cell differentiation and replication under the guidance of her PhD advisor, Dr Peter Chien. Developed deep expertise in protein biochemistry, molecular cloning and microscopy. Other responsibilities include presenting research work at seminars in the laboratory, university and external conferences, contributing to laboratory-wide research and technical discussions, preparing research for… Show more Undertook research aimed at understanding the molecular mechanisms of protein degradation during bacterial cell differentiation and replication under the guidance of her PhD advisor, Dr Peter Chien. Developed deep expertise in protein biochemistry, molecular cloning and microscopy. Other responsibilities include presenting research work at seminars in the laboratory, university and external conferences, contributing to laboratory-wide research and technical discussions, preparing research for publication, assisting in the training of junior PhD students, Masters students and undergraduate students, and contributing to the smooth running of the laboratory communal facilities.

    • Research Assistant
      • Sep 2008 - Apr 2010

      Conducted anaerobic microbial research studies under the guidance of Dr Derek Lovley. Learned to build anaerobic gassing station, culture methanogens and previously unknown anaerobic bacteria from sewage sludge, and conduct experimental evolution experiments using 16S ribosomal RNA sequencing to identify and compare bacteria and archaea diversity. Gained experience in determining microbial metabolism (phenotypic assays, measurements using gas chromatography, high performance liquid… Show more Conducted anaerobic microbial research studies under the guidance of Dr Derek Lovley. Learned to build anaerobic gassing station, culture methanogens and previously unknown anaerobic bacteria from sewage sludge, and conduct experimental evolution experiments using 16S ribosomal RNA sequencing to identify and compare bacteria and archaea diversity. Gained experience in determining microbial metabolism (phenotypic assays, measurements using gas chromatography, high performance liquid chromatography).

    • Research Officer
      • Jul 2005 - Jul 2008

      Worked under the guidance of Dr Jimmy Chao, Dr Peter Morin Nissom, and Dr Lee Yih Yean. Conducted genetic screens for transcription activators in eukaryotic cells (human HEK293, HeLa, Chinese hamster ovary cells). Examined protein interaction partners of transcriptional regulators, and post-translational protein modifications (ubiquitination, neddylation, sumoylation). Trained visiting students from local colleges, managed laboratory resources and purchasing. Was selected for a one year… Show more Worked under the guidance of Dr Jimmy Chao, Dr Peter Morin Nissom, and Dr Lee Yih Yean. Conducted genetic screens for transcription activators in eukaryotic cells (human HEK293, HeLa, Chinese hamster ovary cells). Examined protein interaction partners of transcriptional regulators, and post-translational protein modifications (ubiquitination, neddylation, sumoylation). Trained visiting students from local colleges, managed laboratory resources and purchasing. Was selected for a one year Bioprocessing training program involving hands-on training in molecular genetics, large-scale fermentation (10L, 50L), and downstream processing and quality control for the production of therapeutic recombinant proteins. Show less Worked under the guidance of Dr Jimmy Chao, Dr Peter Morin Nissom, and Dr Lee Yih Yean. Conducted genetic screens for transcription activators in eukaryotic cells (human HEK293, HeLa, Chinese hamster ovary cells). Examined protein interaction partners of transcriptional regulators, and post-translational protein modifications (ubiquitination, neddylation, sumoylation). Trained visiting students from local colleges, managed laboratory resources and purchasing. Was selected for a one year… Show more Worked under the guidance of Dr Jimmy Chao, Dr Peter Morin Nissom, and Dr Lee Yih Yean. Conducted genetic screens for transcription activators in eukaryotic cells (human HEK293, HeLa, Chinese hamster ovary cells). Examined protein interaction partners of transcriptional regulators, and post-translational protein modifications (ubiquitination, neddylation, sumoylation). Trained visiting students from local colleges, managed laboratory resources and purchasing. Was selected for a one year Bioprocessing training program involving hands-on training in molecular genetics, large-scale fermentation (10L, 50L), and downstream processing and quality control for the production of therapeutic recombinant proteins. Show less

    • United States
    • Pharmaceutical Manufacturing
    • 100 - 200 Employee
    • Business Development Intern
      • Jul 2003 - Jun 2004

      Worked under the guidance of Patricia Nasshorn, Vice President of Business Development. Developed financial models to back in-licensing negotiation bids. Consolidated commercial assessments for three in-licensed drug compounds for evaluation by venture capitalists. Prepared therapeutics database to assist search for suitable pharmaceutical compound for in-licensing, and collated gene informational database to assist patenting efforts. Worked under the guidance of Patricia Nasshorn, Vice President of Business Development. Developed financial models to back in-licensing negotiation bids. Consolidated commercial assessments for three in-licensed drug compounds for evaluation by venture capitalists. Prepared therapeutics database to assist search for suitable pharmaceutical compound for in-licensing, and collated gene informational database to assist patenting efforts.

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