Julia Magdalena Michalska
Scientist Optical Connectomics at E11 Bio- Claim this Profile
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Bio
Experience
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E11 Bio
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United States
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Biotechnology Research
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1 - 100 Employee
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Scientist Optical Connectomics
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May 2023 - Present
I am providing expertise on preserving and elucidating brain tissue organization with commercial microscopy tools to facilitate light-microscopy based, scalable circuit mapping for the scientific community. I am providing expertise on preserving and elucidating brain tissue organization with commercial microscopy tools to facilitate light-microscopy based, scalable circuit mapping for the scientific community.
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Institute of Science and Technology Austria
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Austria
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Research Services
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300 - 400 Employee
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Postdoctoral Researcher
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Feb 2023 - Mar 2023
Postdoctoral researcher at the interface of neuroscience and biophysics.
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Researcher PHD Student
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Sep 2017 - Jan 2023
PhD student at the interface of neuroscience and biophysics. I developed and applied super-resolution and molecular techniques to shed light onto the complex composition and connectivity of the nervous system.
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Karolinska Institutet
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Sweden
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Higher Education
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700 & Above Employee
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Research Assistant
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Feb 2016 - Aug 2017
Master thesis & employment as research assistant in the Carmine Belin laboratory: I supported the group in their effort to characterize the neurological condition Cluster Headache by increasing the Swedish bio-bank containing blood, DNA and primary cell samples. In addition, I analyzed the impact of nitric oxide and calcitonin-gene related peptide on this disease by utilizing a range of molecular and genetic techniques, including molecular cloning, qPCR, pyrosequencing, in situ hybridization, as well as protein and small molecule assays. Show less
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Research Assistant
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Oct 2015 - Feb 2016
Laboratory project and research assistant in the Calegari laboratory for the proliferation and differentiation of neural stem cells: I performed lineage tracing of neural progenitor cells in the subventricular zone of a mouse model with shortened cell cycle. I analyzed the cells' proliferation and differentiation processes and tested the model system's applicability for clonal and morphological analysis.
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Research Assistant
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May 2015 - Oct 2015
Research assistant in the Speier laboratory for Diabetes research: In addition to carrying outgeneral laboratory tasks, including mouse handling and genotyping, I assisted in the purification of human beta cells and the analysis of mouse islet physiology.
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Monash University
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Australia
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Higher Education
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700 & Above Employee
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Intern
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Jun 2014 - Sep 2014
4-month internship supervised by Prof. Dr. Milton Hearn in the Center for Green Chemistry: I successfully cloned and expressed C- and N-terminally His-tagged xylanase A in E. coli and tested the purification efficacy of a new immobilized metal affinity chromatography ligand with those proteins. 4-month internship supervised by Prof. Dr. Milton Hearn in the Center for Green Chemistry: I successfully cloned and expressed C- and N-terminally His-tagged xylanase A in E. coli and tested the purification efficacy of a new immobilized metal affinity chromatography ligand with those proteins.
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Bielefeld University
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Germany
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Research
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700 & Above Employee
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Intern
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Oct 2013 - Mar 2014
BSc thesis at the Faculty of Technology supervised by Dr. Joe Max Risse: I improved a multi-stage fermentation system for the optimized growth of E. gracilis and production of vitamin E and paramylon. The goal of the project was to establish a system for the simultaneous production of biomass as a substrate for biogas production, as well as of biomedical products. BSc thesis at the Faculty of Technology supervised by Dr. Joe Max Risse: I improved a multi-stage fermentation system for the optimized growth of E. gracilis and production of vitamin E and paramylon. The goal of the project was to establish a system for the simultaneous production of biomass as a substrate for biogas production, as well as of biomedical products.
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Education
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Institute of Science and Technology Austria
Doctor of Philosophy - PhD, Neuroscience, Biophysics -
Technische Universität Dresden
Master's degree, Molecular Bioengineering -
Bielefeld University
Bachelor's degree, Molecular Biotechnology