Experience

National Institute of General Medical Sciences (NIGMS)

• United States
• Government Administration
• 1 - 100 Employee

• Program Director

  • Oct 2019 - Present

  Manage synthetic chemistry and chemical biology research grant portfolio Manage synthetic chemistry and chemical biology research grant portfolio



Eisai US

• Pharmaceutical Manufacturing
• 700 & Above Employee

• Process Chemist

  • Nov 2017 - Sep 2019

  • Anti-malarial drug development, including developed a crystallization-based scale-up process route and delivered tox-batch of the antimalarial agent BRD5018 • Anti-malarial drug development, including developed a crystallization-based scale-up process route and delivered tox-batch of the antimalarial agent BRD5018



Celgene

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Medicinal Chemist

  • Jan 2015 - Jun 2017

  • Lead chemistry efforts/function as a member of medicinal chemistry teams on early-stage oncology and inflammatory drug discovery projects, develop type I and type II kinase inhibitors and covalent drug-like compounds for protein targets • Manage partnership with chemistry contract research organizations • Lead chemistry efforts/function as a member of medicinal chemistry teams on early-stage oncology and inflammatory drug discovery projects, develop type I and type II kinase inhibitors and covalent drug-like compounds for protein targets • Manage partnership with chemistry contract research organizations



Texas A&M University

• United States
• Higher Education
• 700 & Above Employee

• Assistant Professor of Chemistry

  • Aug 2007 - May 2014

  • Total synthesis of bioactive natural products • Development of new synthetic methods • Biomedical study of therapeutically useful small molecules • Total synthesis of bioactive natural products • Development of new synthetic methods • Biomedical study of therapeutically useful small molecules



Broad Institute of MIT and Harvard

• Research Services
• 700 & Above Employee

• NIH Postdoctoral Fellow

  • Jan 2005 - Jun 2007

  • Developed a high throughput assay of p70 S6K signaling, screened compound libraries to identify inhibitors of the pathway, optimized one of the lead compounds (quinostatin), and identified PI3K to be its primary cellular target • Explored an image-based approach for high throughput screening of small molecule regulators of autophagy • Developed a high throughput assay of p70 S6K signaling, screened compound libraries to identify inhibitors of the pathway, optimized one of the lead compounds (quinostatin), and identified PI3K to be its primary cellular target • Explored an image-based approach for high throughput screening of small molecule regulators of autophagy



Scripps Research

• United States
• Research Services
• 700 & Above Employee

• Postdoctoral Research Associate

  • Oct 2003 - Oct 2004

  • Developed a cell-based reporter gene high throughput assay for the Notch signaling pathway, screened compound libraries to identify small molecule regulators of the pathway, medicinal chemistry optimization of a lead compound • Explored cell-based reporter gene assays for high throughput screening of small molecule regulators of the Hedgehog signaling pathway • Developed a cell-based reporter gene high throughput assay for the Notch signaling pathway, screened compound libraries to identify small molecule regulators of the pathway, medicinal chemistry optimization of a lead compound • Explored cell-based reporter gene assays for high throughput screening of small molecule regulators of the Hedgehog signaling pathway