Jim Griffin
Bioinformatics Scientist at Amber Bio- Claim this Profile
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Experience
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Amber Bio
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Bioinformatics Scientist
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Nov 2022 - Present
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Encoded Therapeutics Inc.
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United States
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Biotechnology Research
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100 - 200 Employee
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Bioinformatics Scientist
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Sep 2020 - Dec 2022
I build NGS pipelines to support gene therapy discovery and pre-clinical development I build NGS pipelines to support gene therapy discovery and pre-clinical development
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Ginkgo Bioworks, Inc.
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United States
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Biotechnology Research
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700 & Above Employee
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Bioinformatics Scientist
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Oct 2018 - Sep 2020
- I analyze short & long read NGS data to assist program teams with genome assembly, strain improvement & validation, variant calling & effect classification, etc. - Led a team to productionize Ginkgo’s long-read sequencing capabilities and scaled throughput 5X from a manual process to a standardized service that assembled 48 microbial genomes per week via wet-lab process changes, data tracking and analysis pipeline development - Developed Illumina and Nanopore based strain verification pipelines to identify repetitive, high copy number, random DNA integration events in challenging hosts - Developed and deployed Dockerized workflows in AWS for a variety of new NGS services including amplicon processing, genome polishing & annotation liftover, comparative genomics applications, RNAseq, and structural variant detection Show less
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Northwestern University
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Philippines
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Higher Education
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1 - 100 Employee
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PHD Candidate
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Sep 2013 - Sep 2018
Researched microbial community assembly mechanisms using next-generation sequencing data. Designed and built workflows for taxonomic clustering and analysis of community diversity using Python, R and bash. Studied exoelectrogenic biofilm composition and functional responses to shifts in carbon feed sources. Researched microbial community assembly mechanisms using next-generation sequencing data. Designed and built workflows for taxonomic clustering and analysis of community diversity using Python, R and bash. Studied exoelectrogenic biofilm composition and functional responses to shifts in carbon feed sources.
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Analyst
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2012 - 2013
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Education
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Massachusetts Institute of Technology
Bachelor of Science - BS, Chemical Engineering -
Northwestern University
Doctor of Philosophy - PhD, Chemical Engineering