Jigisha Shah, Ph.D.
Senior Manager, Regulatory Affairs at RAPT Therapeutics- Claim this Profile
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Bio
Experience
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RAPT Therapeutics
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Biotechnology Research
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100 - 200 Employee
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Senior Manager, Regulatory Affairs
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Oct 2023 - Present
South San Francisco, California, United States
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Cytokinetics
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United States
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Biotechnology Research
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200 - 300 Employee
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Senior Manager Regulatory Affairs
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Mar 2023 - Oct 2023
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Manager, Regulatory Affairs
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Jul 2020 - Mar 2023
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Regulatory Affairs Associate
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Jul 2018 - Jun 2020
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Intern, Regulatory Affairs
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2017 - Jul 2018
San Francisco Bay Area
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Silicon Valley ACS Section
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United States
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Non-profit Organizations
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Past Chair
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Jan 2022 - Mar 2023
Silicon Valley, California, United States
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Volochem
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United States
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Research Services
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1 - 100 Employee
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Scientist
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Jun 2017 - Aug 2017
Led synthetic route design, synthesis, characterization and purification of novel drug-like compounds, medicinal chemistry intermediates/ building blocks for custom synthesis projects from milligram to multigram scale through multi-step synthesis Defined process development for chemical intermediates and drug-like substances Performed chemical reactions, isolations, separations, purifications, and crystallizations Conducted route scouting, reaction optimization, and… Show more Led synthetic route design, synthesis, characterization and purification of novel drug-like compounds, medicinal chemistry intermediates/ building blocks for custom synthesis projects from milligram to multigram scale through multi-step synthesis Defined process development for chemical intermediates and drug-like substances Performed chemical reactions, isolations, separations, purifications, and crystallizations Conducted route scouting, reaction optimization, and scale-ups Wrote concise procedures and reports to enable successful technology transfers Summarized/interpreted data and communicated results in research meetings in a team-based environment Managed lab resources by sourcing, ordering and inventory maintainence Show less
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San Jose City College
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United States
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Higher Education
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300 - 400 Employee
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Adjunct Faculty
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Jan 2017 - Jun 2017
San Francisco Bay Area
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Syracuse University
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United States
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Higher Education
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700 & Above Employee
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Research Assistant
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Jan 2010 - Jun 2016
Syracuse, New York Area Developed and optimized the Friedel Craft’s reaction of indoles with trichloroacetimidates. Discovered the effects of Steric bulk in trichloroacetimidate moiety on regioselectivity of these reactions. Studied alkylation of 3-substituted indole derivatives and tryptamines with trichloroacetimidates which provided practical opportunity for rapid construction of pyrrolidino[2,3-b]indoline. Investigated N-Alkylation of 2,3 disubstituted indoles and their rearrangement to furnish C-3… Show more Developed and optimized the Friedel Craft’s reaction of indoles with trichloroacetimidates. Discovered the effects of Steric bulk in trichloroacetimidate moiety on regioselectivity of these reactions. Studied alkylation of 3-substituted indole derivatives and tryptamines with trichloroacetimidates which provided practical opportunity for rapid construction of pyrrolidino[2,3-b]indoline. Investigated N-Alkylation of 2,3 disubstituted indoles and their rearrangement to furnish C-3 alkylated compounds. Introduced new technology for protection of carboxylic acids under relatively neutral reaction conditions using 4-methoxybenzyl trichloroacetimidate and diphenylmethyl trichloroacetimidate. Designed, modified and optimized multiple synthetic routes for efficient and safe scale up of lead molecule, which met initial requirements for Tryptamine based SHIP inhibitor. Developed a diverse library of SHIP inhibitors.
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Teaching Assistant
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Aug 2009 - Apr 2011
Syracuse, New York Area Assisted with curriculum and course material development for General and Organic Chemistry Led recitation/laboratory sections and assisted students in understanding laboratory chemicals, equipment, experimental procedures and safety
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Fergusson College
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India
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Higher Education
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100 - 200 Employee
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Assistant Professor
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Jul 2008 - Jul 2009
Pune Area, India Taught undergraduate and graduate courses ranging in size from 10-120 students. Topics included: current research in General and Organic Chemistry, Synthetic Organic Chemistry, science and cooking Prepared course material including laboratory experiments, lectures, exams, homework, and practice problems Mentored students in their research projects
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National Chemical Laboratory
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Research Services
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700 & Above Employee
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Project Student/Intern
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Jun 2007 - May 2008
Pune Area, India Worked on synthesis of an amide alkaloid natural product obtained from the roots of piper nigrum.
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Education
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Syracuse University
Doctor of Philosophy (Ph.D.), Chemistry -
Fergusson College
Masters in Science (M.Sc.), Organic Chemistry -
Fergusson College
Bachelor of Science (B.Sc.), Chemistry -
St. Lawrence, Aurangabad