Senior Engineer

• Aug 2023 - Present

Graduate Research Assistant

• Sep 2017 - Aug 2023

In this current role, my core responsibility is to deliver exceptional technical expertise in organ-on-chip design and fabrication. Here, I prepare highly productive work plans in accordance with research objectives. Noted Accomplishments:Design of Multiwells plate lung chip system for drug screening:• I architected and fabricated a 96-well plate microfluidic chip system that mimics alveoli by providing microfluidics, mechanical stretching, and heterogeneity.• Microfluidics related to mimicking microvascular around alveoli; mechanical stretching for mimicking deformation of alveoli when breathing; and co-cultured in the system to replicate morphology of micro-environment of cells in alveoli.Development of Blood-brain barrier on chip:• I established an in-vitro platform that closely resembled the BBB microenvironments in humans. I manufactured an electrospun fiber to mimic basal membrane of microvasuclar. The platform has the potential to use central nervous system (CNS）disease drug screening.Glaucoma on Chip:• I designed a glaucoma chip containing intraocular pressure control and fibrous cornea structure. Utilized electro-spun fiber to mimic fibrous layer or cornea and used pneumatic pressure to mimic the high eye pressure (a potential cause of glaucoma).Fluidic Simulation:• I performed microfluidic simulation for organoid culture in perfusion plate. Evaluated Volume flow rate, shear stress, and flow velocity based on SolidWorks flow simulation and COMSOL.• I rebuilt the 3D CAD design for two plate types (36 wells and 144 wells) and configured simulation model for plates (static and on rocker). Micro/Nanofabrication:• I fabricated sub-micro grating in cleanroom e-beam lithography for using stem cell fate and function.• I forged electro spinning fibers in different guidance to create aligned, mesh and random shape for endothelial and epithelial cell study. Show less

Teaching Assistant

• Aug 2020 - Dec 2022

In this previous role, my noted accomplishment include:BMEN 4320/5324 biomedical microelectromechanical systems (BioMEMS):I prepared laboratory lessons about BioMEMS micro/nano manufacturing. I also formalized two bioMEMS systems through laser cutting and 3D printing. Further, I performed comprehensive cell studies in the systems to develop a thorough understanding of biological aspects.BMEN 4310/5315 Computational Methods in Biomedical Engineering:I taught a number of students on the basics of MATLAB simulation software and how to use MATLAB to correlate mathematic models with biology phenomena such as neural signal transformation and cell potential.BMEN 5210 Biomedical Engineering Laboratory:I up-skilled students with basic skills in cell studying, including cell culture, microscope, and immunofluorescence staining. Show less

Research And Development Scientist

• May 2014 - Dec 2017

During my time as a Research Scientist, I engineered an innovative anti-reflective (AR) coating in the aqueous phase of cover glass for solar panels by using core-shell particles that increased characters of transmission, hydrophobicity, and durability. The patent published the product and generated $20M per year for the organization. • I developed an easy-to-use test kit by encapsulating color indicator in polyurethane onto a microfluidic chip for sterilizing procedures, including OPA and hydrogen peroxide sterilization to verify the sterility of medical tools. Show less