Head of Synthesiser Technology, Senior Engineer

• May 2022 - Present

Chemical Engineer

• Dec 2020 - May 2022

Develop and advance liquid phase oligonucleotide synthesis - focus on process technology development and automationDevelop organic nanofiltration technology and produce membranes for filtration

PhD Candidate

• May 2017 - Nov 2020

• Advancing the conventional liquid phase peptide synthesis (LPPS) with nanostar-sieving platform, to improve the manufacturing of peptide drugs. - Collaborated with U.S. Pharma- Eli Lilly & Co. to develop a lab-scale nanostar-sieving synthesiser, which can produce high-purity peptide crudes at lower cost than the conventional solid-phase method. - Designed the synthesier and developed organic solvent nanofiltratio membranes for purifications. - Developed and optimised the synthesis routes for producing nanostar with various functionalities.- Lead author of publication in Angewandte Chemie (IF >12).• Joined PharmaSEL, a £5m virtual lab formed by Imperial, University College London and Eli Lilly. The lab aims to transform drugs manufacturing via process system engineering.- Focus on process automation with in-situ real-time analytics. - Study solubilities using a modelling approach. • Experienced in using computational simulation to assist in process developments. Recent works include: - Optimised the organic solvent nanofiltration (OSN) process of nanostar-sieving synthesiser using MATLAB. - Modelled biodiesel distillation processes using Aspen for a project sponsored by British Petroleum. Published in Energy and Environmental Science (2020 IF >33) as co-author.• Manage the analytical lab in the Livingston Group. - Manage analytical devices: Acquity Waters UPLC, Agilent’s LC-MS, HPLC and ELSD. Show less

Graduate Teaching Assistant

• May 2017 - Sep 2020

Teach MATLAB computing undergraduate courses.

Research Assistant

• Dec 2016 - Apr 2017

• Contract research assistant. - Worked with postdoctoral fellow to develop a modelling approach to improve the spectral resolution of benchtop NMR spectrometer, economical and robust device for QC analysis. Published in the Journal of Magnetic Resonance.• Summer researcher- Awarded the Summer Research Scholarship (NZD$5k) to work on a 6-week project on controlled-release fertilisers. Developed a model to study the water-transport across the fertiliser coating.

Teaching Assistant

• Jul 2015 - Dec 2016

• Designed and supervised MATLAB computing undergraduate courses.

Intern

• Nov 2015 - Feb 2016

Responsible for engineering services to the assets of a joint venture between Shell, Todd and OMV in Taranaki. • Highlight: Created the first-of-its-kind Equipment Levels Diagram to display all equipment’s level details across different technical documents into one graphical interface. Instant information access improved the team’s productivity. • Other practical experiences include: 1. Process documentation and safety: - Updating/drafting Cause & Effect (C&E) matrices and cross-checking the C&E with the ESD logic diagram for plant shutdown hierarchy. - Updating PFD and P&ID diagrams. - Reviewing and updating the safeguarding manuals. 2 .Process operation and control: - Valve sizing and validation. - Site inspections with process engineers. Show less

Operations Intern

• Nov 2014 - Feb 2015

Joined the operation department at Malaysia LNG (MLNG) which executes the operation of Petronas LNG complex. • Highlight: Created a model to monitor the flaring system at MLNG Satu plant at real-time, which was used to identify and track unusual flaring activities. The aim was to lower emissions and increase revenue. • Other practical experiences include: 1. Updating P&ID diagrams 2. Assisted the operation engineers in plant operations. Joined the operation department at Malaysia LNG (MLNG) which executes the operation of Petronas LNG complex. • Highlight: Created a model to monitor the flaring system at MLNG Satu plant at real-time, which was used to identify and track unusual flaring activities. The aim was to lower emissions and increase revenue. • Other practical experiences include: 1. Updating P&ID diagrams 2. Assisted the operation engineers in plant operations.