Jesslyn Ong
Research Officer, Translational Control of Disease Lab at Skin Research Institute of Singapore (SRIS)- Claim this Profile
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Bio
Credentials
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Responsible Care and Use of Laboratory Animals Course (RCULAC)
A*STAR - Agency for Science, Technology and ResearchDec, 2021- Nov, 2024 -
Business Continuity Management Training
DeloitteNov, 2021- Nov, 2024 -
N3 Laser Operation License
National Environment AgencyNov, 2021- Nov, 2024
Experience
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Skin Research Institute of Singapore (SRIS)
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Singapore
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Research Services
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1 - 100 Employee
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Research Officer, Translational Control of Disease Lab
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2021 - Present
Research involves using human embryonic stem cell-derived neurons to study long non-coding RNA (lncRNAs) expression in mammalian HOX genes and the role of lncRNAs in developmental abnormalities and neurodegenerative diseases. Culturing and analyzing hES-cells, neuronal progenitor cells and neurons through chromatin immunoprecipitation (ChIP), fluorescence in-situ hybridization (FISH) and qPCR techniques Animal handling Co-culturing hESC-derived neurons with primary astrocytes obtained from mouse brain models to study neuronal activity using electrphysiology techniques. Show less
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National University Hospital
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Singapore
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Hospitals and Health Care
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700 & Above Employee
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Medical Technologist, Haematology-Oncology
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2018 - 2020
Collaborated with Genome Institute of Singapore (GIS), A*STAR to investigate the role of novel oncogenic factors in ER+/HER2-, HER2+ and Triple Negative breast cancers, and the role of protein inhibition in solid tumours by performing molecular biology experiments such as cell line culture, chemotherapy drug treatment assays, tumourspheres, droplet digital PCR, and other protein studies. Under this clinical research, I have submitted an abstract for this study and was selected for NCAM 2020's Basic Science poster presentation. Other work: Tumour processing from mice models to prepare for downstream IHC staining, and investigating novel immunotherapy drug treatment on breast and liver cancer cells. Show less
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Procter & Gamble
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United States
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Manufacturing
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700 & Above Employee
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Associate Researcher, Beauty Measurement Sciences, R&D
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2018 - 2018
Method owner for end scattering analysis in hair care R&D team R&D support for APAC hair care consumer goods Method owner for end scattering analysis in hair care R&D team R&D support for APAC hair care consumer goods
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Singapore Institute of Manufacturing Technology
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Singapore
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Research
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200 - 300 Employee
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Laboratory Officer, Bio-Manufacturing Programme
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2016 - 2018
Conducted bio-lab safety training and technical training in cell culture, formulation of hydrogels and lyophilization to new hires, students and other research professionals. Other lab manager duties: Procurement, setup of new biology labs, establishing SOP and RA/SWP documents for biological equipment and processes, enforcing lab safety rules and proper upkeep of laboratory. Contributed as team member in the following research projects: - A label-free, non-destructive method of cell monitoring by exploiting autofluorescence properties found in cells by studying mitochondria and cell redox reaction (2016-2018) - Development of bioinks obtained through animal-derived organ decellularization and formulation of hydrogels for use 3D bioprinting (2016-2017) Show less
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Merck
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Pharmaceutical Technician, Merck Production System
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2014 - 2015
Manufactured solid dose medicines sold in more than 140 countries in compliance with cGMP standards Operated high-speed tablet compression machine and performed troubleshooting on compression procedure errors Performed QC checks on pharmaceutical tablets for API content identification Manufactured solid dose medicines sold in more than 140 countries in compliance with cGMP standards Operated high-speed tablet compression machine and performed troubleshooting on compression procedure errors Performed QC checks on pharmaceutical tablets for API content identification
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Education
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La Trobe University
Bachelor's degree, Biomedical Science -
Republic Polytechnic
Diploma, Biotechnology