Jesko Wagner

PHD Candidate at MRC Human Genetics Unit at the University of Edinburgh
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Contact Information
us****@****om
(386) 825-5501
Location
Edinburgh, Scotland, United Kingdom, UK
Languages
  • English Full professional proficiency
  • German Native or bilingual proficiency
  • Dutch Elementary proficiency

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Credentials

  • Building Deep Learning Applications with Keras 2.0
    LinkedIn
    Jan, 2022
    - Oct, 2024
  • Transfer Learning for Images Using PyTorch: Essential Training
    LinkedIn
    Jan, 2022
    - Oct, 2024

Experience

  • MRC Human Genetics Unit at the University of Edinburgh
    • Research Services
    • 1 - 100 Employee
    • PHD Candidate
      • Sep 2021 - Present

      PhD candidate of the MRC four-year International PhD programme in Human Genetics, Genomics and Disease. Researching how to improve morphological profiling to find better drugs faster. Building on rigorous statistics of high-throughput single-cell data. PhD candidate of the MRC four-year International PhD programme in Human Genetics, Genomics and Disease. Researching how to improve morphological profiling to find better drugs faster. Building on rigorous statistics of high-throughput single-cell data.

  • EMBL
    • Germany
    • Research Services
    • 700 & Above Employee
    • Research Internship
      • Mar 2021 - Aug 2021

      Research project with group of Jan Korbel to assess functional impact of structural variations in single cells. Research project with group of Jan Korbel to assess functional impact of structural variations in single cells.

  • VIB
    • Belgium
    • Research
    • 700 & Above Employee
    • Literature Intern
      • Dec 2020 - Feb 2021

      Literature internship with the Stein Aerts group, reviewing transcription factor motif discovery and enrichment, particularly in the single-cell era. Literature internship with the Stein Aerts group, reviewing transcription factor motif discovery and enrichment, particularly in the single-cell era.

  • UMC Utrecht
    • Netherlands
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Intern
      • Dec 2019 - Nov 2020

      Research project with Jeroen de Ridder on detection of genome-wide structural-variant signatures caused by gene deficiencies using machine-learning. Designed and implemented R/Python pipeline (using snakemake), elucidating mechanism and impact of CDK12 deficiency. Obtained grade: 8.6 (A+) Research project with Jeroen de Ridder on detection of genome-wide structural-variant signatures caused by gene deficiencies using machine-learning. Designed and implemented R/Python pipeline (using snakemake), elucidating mechanism and impact of CDK12 deficiency. Obtained grade: 8.6 (A+)

  • SciLifeLab
    • Sweden
    • Biotechnology Research
    • 200 - 300 Employee
    • Research Intern
      • Feb 2019 - Aug 2019

      Bioinformatics project in the Crosetto group revolving around double-strand breaks, their involvement in genome fragility and effects on transcription in various biological contexts. Bioinformatics project in the Crosetto group revolving around double-strand breaks, their involvement in genome fragility and effects on transcription in various biological contexts.

  • Maastricht UMC+
    • Netherlands
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Intern
      • Sep 2018 - Jan 2019

      Internship for strengthening of bioanalytical skills. Research was focused on bioinformatical pipeline development with R and bash. Main focus was on single-cell transcriptomics, methylation and accessibility profiling. Previously worked on improving efficiency of microRNA alignments. Internship for strengthening of bioanalytical skills. Research was focused on bioinformatical pipeline development with R and bash. Main focus was on single-cell transcriptomics, methylation and accessibility profiling. Previously worked on improving efficiency of microRNA alignments.

  • DKFZ German Cancer Research Center
    • Germany
    • Research Services
    • 700 & Above Employee
    • Bachelor Thesis
      • Feb 2018 - Jun 2018

      Bachelor thesis research performed full-time at the German Cancer Research Center under kind supervision of Prof. Dr. Claudia Scholl. Research aimed at determining oncogenic potential of KRAS-like mutations in human cells and was conducted in vitro in BS1 and BS2 laboratories. Obtained grade: 9.1 (A+) Bachelor thesis research performed full-time at the German Cancer Research Center under kind supervision of Prof. Dr. Claudia Scholl. Research aimed at determining oncogenic potential of KRAS-like mutations in human cells and was conducted in vitro in BS1 and BS2 laboratories. Obtained grade: 9.1 (A+)

  • Maastricht University
    • Netherlands
    • Higher Education
    • 700 & Above Employee
    • Research Intern
      • Jan 2018 - Feb 2018

      Internship for university research project. Research was conducted in the field of Computational Biology using MatLab. Search strategy optimization was performed using a genetic algorithm. Research was performed in a group of 8 students. Obtained grade: 8.5 (A) Internship for university research project. Research was conducted in the field of Computational Biology using MatLab. Search strategy optimization was performed using a genetic algorithm. Research was performed in a group of 8 students. Obtained grade: 8.5 (A)

  • Aperture Study Association
    • President of Study Association
      • Jul 2016 - Jul 2017

      Aperture is the official MSP study association. The goal of Aperture is to make the academic year as fun, interesting and educational as possible for the MSP students. Throughout the year, Aperture organizes a number of events, such as voluntary lectures, study trips, and board game nights. As the president of Aperture, I was in charge of day-to-day supervision and management of the board of the association. Next to this, I was responsible for the communication and representation of the association towards external parties, which left me with excellent professional communication skills. The budgeting and funding of the association were also part of my function, in close collaboration with the Aperture treasurer. Next to this, I was in charge of the organization of the study trip to Heidelberg. Visits to the various Max Planck Institutes in Heidelberg as well as the European Molecular Biology Laboratory were organized for this inter-disciplinary scientific study trip. Show less

  • Maastricht UMC+
    • Netherlands
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Intern
      • Jun 2017 - Jun 2017

      Internship for university research project. Research was conducted into the effects of knockdown of microRNAs on obesity and cardiovascular health. Worked together in a group of 6 students. Obtained grade: 8.3 (A) Internship for university research project. Research was conducted into the effects of knockdown of microRNAs on obesity and cardiovascular health. Worked together in a group of 6 students. Obtained grade: 8.3 (A)

Education

  • The University of Edinburgh
    Doctor of Philosophy - PhD, Genome Sciences/Genomics
    2021 - 2025
  • Utrecht University
    Master of Science - M.Sc., Bioinformatics
    2019 - 2021
  • Maastricht University
    Bachelor of Science - B.Sc., Liberal Arts and Sciences, 8.2 (A)
    2015 - 2018

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