Manufacturing Manager

• Sep 2017 - Present

Scientific Associate (Mosnier Lab)

• Jun 2016 - Sep 2017

Translational research on a novel therapy for malaria using a transgenic mouse model that expresses human-endothelial protein C receptors (h-EPCR). Dose-response and time course evaluations of the injected malaria protein have yielded valuable information about the humanized-mouse model and further work is being done to understand the interaction of the malaria protein expressed by the parasite and the h-EPCR in our transgenic mouse model. In addition, we are working to establish the ability… Show more Translational research on a novel therapy for malaria using a transgenic mouse model that expresses human-endothelial protein C receptors (h-EPCR). Dose-response and time course evaluations of the injected malaria protein have yielded valuable information about the humanized-mouse model and further work is being done to understand the interaction of the malaria protein expressed by the parasite and the h-EPCR in our transgenic mouse model. In addition, we are working to establish the ability of a mutated soluable EPCR to compete for binding of the malaria protein with transgenic expression of h-EPCR.

Scientific Associate (Yagi Lab)

• Aug 2013 - May 2016

Evaluate a novel gene therapy for mitochondrial disorders using an optokinetic behavioral test to evaluate the development of the Leber's Hereditary Optic Neuropathy (LHON) model in rats following interocular injections of mutated genes. - Developed behavioral tests used in the lab for assessment of both an acute and chronic MPTP Parkinson’s disease (PD) model in mice during earlier studies that utilized the same gene therapy in both cell culture and animal models. - Devised new methods… Show more Evaluate a novel gene therapy for mitochondrial disorders using an optokinetic behavioral test to evaluate the development of the Leber's Hereditary Optic Neuropathy (LHON) model in rats following interocular injections of mutated genes. - Developed behavioral tests used in the lab for assessment of both an acute and chronic MPTP Parkinson’s disease (PD) model in mice during earlier studies that utilized the same gene therapy in both cell culture and animal models. - Devised new methods for the analysis of brain homogenates that allowed for HPLC and western blotting experiments from a single sample. - Served as the group editor of grammar and phrasing for manuscripts and abstracts.

Postdoctoral Research Associate

• May 2005 - Oct 2008

Evaluated a novel gene therapy for mitochondrial disorders using a Parkinson's disease (PD) model in both cell culture and animal models. Developed behavioral tests used in the lab for assessment of both an acute and chronic MPTP PD model in mice. Devised new methods for the analysis of brain homogenates; allowing for HPLC and western blotting experiments from a single sample. Served as the group editor of grammar and phrasing for manuscripts and abstracts. Evaluated a novel gene therapy for mitochondrial disorders using a Parkinson's disease (PD) model in both cell culture and animal models. Developed behavioral tests used in the lab for assessment of both an acute and chronic MPTP PD model in mice. Devised new methods for the analysis of brain homogenates; allowing for HPLC and western blotting experiments from a single sample. Served as the group editor of grammar and phrasing for manuscripts and abstracts.

Graduate student

• Aug 1999 - Apr 2005

Trained new users (both students and industrial users) on the procedures and equipment required for a novel microfluidic device, including developing and running microfluidic workshops for outside groups of 5 to 6 people. Collected biological samples from freely behaving animals using push-pull perfusion. Taught new graduate students, in a 1:1 setting, the proper techniques for stereotaxic and cannulation surgery in rats. Optimized conditions for the separation of monoamines and metabolites… Show more Trained new users (both students and industrial users) on the procedures and equipment required for a novel microfluidic device, including developing and running microfluidic workshops for outside groups of 5 to 6 people. Collected biological samples from freely behaving animals using push-pull perfusion. Taught new graduate students, in a 1:1 setting, the proper techniques for stereotaxic and cannulation surgery in rats. Optimized conditions for the separation of monoamines and metabolites for the analysis of 1 μL sample volumes in a standard HPLC instrument. - Designed and implemented novel microfabrication methods utilized to create microfluidic devices for the analysis of small-volume biological samples in the university’s microfabrication facility. - As a founding member of the Shippy group, researched and planned equipment purchases, including analytical detectors and optical parts, as well as standard laboratory equipment. Show less Trained new users (both students and industrial users) on the procedures and equipment required for a novel microfluidic device, including developing and running microfluidic workshops for outside groups of 5 to 6 people. Collected biological samples from freely behaving animals using push-pull perfusion. Taught new graduate students, in a 1:1 setting, the proper techniques for stereotaxic and cannulation surgery in rats. Optimized conditions for the separation of monoamines and metabolites… Show more Trained new users (both students and industrial users) on the procedures and equipment required for a novel microfluidic device, including developing and running microfluidic workshops for outside groups of 5 to 6 people. Collected biological samples from freely behaving animals using push-pull perfusion. Taught new graduate students, in a 1:1 setting, the proper techniques for stereotaxic and cannulation surgery in rats. Optimized conditions for the separation of monoamines and metabolites for the analysis of 1 μL sample volumes in a standard HPLC instrument. - Designed and implemented novel microfabrication methods utilized to create microfluidic devices for the analysis of small-volume biological samples in the university’s microfabrication facility. - As a founding member of the Shippy group, researched and planned equipment purchases, including analytical detectors and optical parts, as well as standard laboratory equipment. Show less

MS Physical Chemistry

• May 1997 - Apr 1999

Evaulated the amphiphilic association structures of 3- component systems containing water, surfactants/polymers and fragrance. Evaulated the amphiphilic association structures of 3- component systems containing water, surfactants/polymers and fragrance.