Jason Yamada-Hanff

Principal Bioinformatics Scientist at Tempus Labs, Inc.
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Contact Information
us****@****om
(386) 825-5501
Location
US

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Credentials

  • Regression Models
    Coursera
    Jan, 2018
    - Nov, 2024
  • Exploratory Data Analysis
    Coursera
    Aug, 2017
    - Nov, 2024
  • Statistical Inference
    Coursera
    Aug, 2017
    - Nov, 2024
  • Getting and Cleaning Data
    Coursera
    Jul, 2017
    - Nov, 2024
  • R Programming
    Coursera
    Jul, 2017
    - Nov, 2024
  • The Data Scientist's Toolbox
    Coursera
    Jun, 2017
    - Nov, 2024
  • Machine Learning
    Coursera
    Mar, 2016
    - Nov, 2024

Experience

    • United States
    • Biotechnology Research
    • 700 & Above Employee
    • Principal Bioinformatics Scientist
      • Feb 2023 - Present

    • Senior Bioinformatics Scientist
      • Nov 2021 - Mar 2023

    • United States
    • Research
    • 1 - 100 Employee
    • Director, Software and Data Science
      • Apr 2021 - Nov 2021

      * Lead software, algorithm, and device development across diverse portfolio, with a focus in biomedicine and computer vision.* Train and supervise team of software developers and data scientists.* Drive quality and reproducibility across development lifecycle.

    • Senior Software Developer
      • Feb 2019 - Apr 2021

      * Designed and led architecture for vTag line of machine vision devices and cloud service (Python/C++, PostgreSQL, AWS, Flask, WebSockets).* Reduced per-part vTag image processing time and system cycle time by 10×–30×.

    • Senior Scientist
      • Aug 2017 - Apr 2021

      * Developed small RNA-Seq bioinformatics pipeline supporting identification of circulating miRNA biomarkers (nextflow, docker, Python).* Performed statistical and machine learning modeling to identify small RNA biomarkers of radiation response (R, Python. Key methods: survival analysis, differential expression, bootstrapping, clustering).* Reduced memory usage of commercial Qiagen QiaSEQ analysis by 100×.

    • United States
    • Transportation, Logistics, Supply Chain and Storage
    • 1 - 100 Employee
    • Senior Software Developer
      • Feb 2019 - Apr 2021

    • Bioinformatics Consultant
      • Jan 2017 - Aug 2017

    • Higher Education
    • 1 - 100 Employee
    • Research, PhD Candidate
      • 2010 - Mar 2015

      * Studying the ionic basis of neuronal excitability * PhD Thesis: Regulation of hippocampal pyramidal neuron excitability by subthreshold voltage-dependent conductances * Designed biophysical neuron simulation framework using Markov models and Gillespie’s algorithm for fast stochastic performance. Written in modern Fortran, with Python/NumPy prototype. * Wrote open-source data access library in C for proprietary binary format. * Modernized and integrated legacy codebase and language by designing a modular data analysis toolbox API for Igor Pro language. * Released first native unit test framework for the Igor Pro language. Show less

  • Harvard HPREP, Outreach Program
    • Harvard Medical School, Boston, MA
    • Co Director
      • Sep 2012 - Jan 2015

      * Managed over 100 teachers serving 60 underserved high school students each season. * Grew program five-fold. * Developed new inquiry-based health sciences curriculum and practices. * Managed over 100 teachers serving 60 underserved high school students each season. * Grew program five-fold. * Developed new inquiry-based health sciences curriculum and practices.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Associate
      • 2007 - 2009

      * Studied activity and regulation of the yeast phosphoinositide 4-phosphatase, Sac1p. * Managed technical staff * Wrote full-stack lab information management system (LIMS). in Python/Pylons for tracking scientific resources across institute, with custom PostgreSQL database and Lucene-based search. In daily use for 6 years. * Studied activity and regulation of the yeast phosphoinositide 4-phosphatase, Sac1p. * Managed technical staff * Wrote full-stack lab information management system (LIMS). in Python/Pylons for tracking scientific resources across institute, with custom PostgreSQL database and Lucene-based search. In daily use for 6 years.

    • Teaching Assistant
      • 2006 - 2007

    • Writing Tutor
      • 2004 - 2007

Education

  • Harvard Medical School
    Doctor of Philosophy (PhD), Neuroscience
    2009 - 2015
  • Swarthmore College
    Bachelor of Arts (BA), Biology
    2003 - 2007

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