Jason Yamada-Hanff
Principal Bioinformatics Scientist at Tempus Labs, Inc.- Claim this Profile
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Bio
Credentials
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Regression Models
CourseraJan, 2018- Nov, 2024 -
Exploratory Data Analysis
CourseraAug, 2017- Nov, 2024 -
Statistical Inference
CourseraAug, 2017- Nov, 2024 -
Getting and Cleaning Data
CourseraJul, 2017- Nov, 2024 -
R Programming
CourseraJul, 2017- Nov, 2024 -
The Data Scientist's Toolbox
CourseraJun, 2017- Nov, 2024 -
Machine Learning
CourseraMar, 2016- Nov, 2024
Experience
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Tempus Labs, Inc.
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United States
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Biotechnology Research
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700 & Above Employee
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Principal Bioinformatics Scientist
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Feb 2023 - Present
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Senior Bioinformatics Scientist
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Nov 2021 - Mar 2023
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ChromoLogic LLC
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United States
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Research
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1 - 100 Employee
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Director, Software and Data Science
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Apr 2021 - Nov 2021
* Lead software, algorithm, and device development across diverse portfolio, with a focus in biomedicine and computer vision.* Train and supervise team of software developers and data scientists.* Drive quality and reproducibility across development lifecycle.
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Senior Software Developer
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Feb 2019 - Apr 2021
* Designed and led architecture for vTag line of machine vision devices and cloud service (Python/C++, PostgreSQL, AWS, Flask, WebSockets).* Reduced per-part vTag image processing time and system cycle time by 10×–30×.
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Senior Scientist
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Aug 2017 - Apr 2021
* Developed small RNA-Seq bioinformatics pipeline supporting identification of circulating miRNA biomarkers (nextflow, docker, Python).* Performed statistical and machine learning modeling to identify small RNA biomarkers of radiation response (R, Python. Key methods: survival analysis, differential expression, bootstrapping, clustering).* Reduced memory usage of commercial Qiagen QiaSEQ analysis by 100×.
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Covisus Inc.
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United States
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Transportation, Logistics, Supply Chain and Storage
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1 - 100 Employee
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Senior Software Developer
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Feb 2019 - Apr 2021
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Bioinformatics Consultant
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Jan 2017 - Aug 2017
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Harvard Division of Medical Sciences
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Higher Education
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1 - 100 Employee
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Research, PhD Candidate
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2010 - Mar 2015
* Studying the ionic basis of neuronal excitability * PhD Thesis: Regulation of hippocampal pyramidal neuron excitability by subthreshold voltage-dependent conductances * Designed biophysical neuron simulation framework using Markov models and Gillespie’s algorithm for fast stochastic performance. Written in modern Fortran, with Python/NumPy prototype. * Wrote open-source data access library in C for proprietary binary format. * Modernized and integrated legacy codebase and language by designing a modular data analysis toolbox API for Igor Pro language. * Released first native unit test framework for the Igor Pro language. Show less
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Harvard HPREP, Outreach Program
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Harvard Medical School, Boston, MA
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Co Director
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Sep 2012 - Jan 2015
* Managed over 100 teachers serving 60 underserved high school students each season. * Grew program five-fold. * Developed new inquiry-based health sciences curriculum and practices. * Managed over 100 teachers serving 60 underserved high school students each season. * Grew program five-fold. * Developed new inquiry-based health sciences curriculum and practices.
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Cornell University
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United States
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Higher Education
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700 & Above Employee
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Research Associate
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2007 - 2009
* Studied activity and regulation of the yeast phosphoinositide 4-phosphatase, Sac1p. * Managed technical staff * Wrote full-stack lab information management system (LIMS). in Python/Pylons for tracking scientific resources across institute, with custom PostgreSQL database and Lucene-based search. In daily use for 6 years. * Studied activity and regulation of the yeast phosphoinositide 4-phosphatase, Sac1p. * Managed technical staff * Wrote full-stack lab information management system (LIMS). in Python/Pylons for tracking scientific resources across institute, with custom PostgreSQL database and Lucene-based search. In daily use for 6 years.
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Teaching Assistant
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2006 - 2007
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Writing Tutor
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2004 - 2007
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Education
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Harvard Medical School
Doctor of Philosophy (PhD), Neuroscience -
Swarthmore College
Bachelor of Arts (BA), Biology