Experience

Quality Chemicals

• Spain
• Chemical Manufacturing
• 1 - 100 Employee

• Technical Director

  • Apr 2022 - Present



Uriach

• Spain
• Pharmaceutical Manufacturing
• 200 - 300 Employee

• • Oct 2019 - May 2022

  Leading key projects within the R&D area to support business goals, understanding costumer/market necessities, and all according to project timings and budget. Research, design, evaluate and deliver synthetic routes for new products to increase company portfolio in agreement with other business areas. Determine project goals and priorities by collaborating with Business unit and Operations. Monitoring project performance and objectives to ensure successful goals achievement, generating KPIs and target records.Enhance the Chemical development department abilities, by investigating new technologies (PATs, flow chemistry), active growth opportunities for individuals through specific training or by establishing new business relationships within the Life Science industry (NDA agreements, project collaborations, synthetic partners, external advisors). All according to a route plan settled after evaluating the department necessities and market opportunities.Department procedures’ creation to implement Good Laboratory Practises, increase traceability and improve technology transfers within the company. Edition of documentation packages to maximise process robustness and minimise information loss.Achievements Planning and delivery one fully integrated project (average batch size 20kg), implementing a new synthetic route in compliance with actual regulations. Edition of operational procedures to increase robustness and adapt old methodologies to new international regulations (EMA, ICH, FDA, CSCL). Creation of a skills plan to promote growth. Acquire new instrumentations to adapt the lab necessities to new developments in accordance with manufacturing to make the projects more transferable (Kilolab, H-Cube) and easier to monitor (PATs). Show less

• • Jan 2017 - Oct 2019

  Development, planning and validation of new routes for the synthesis of active pharmaceutical ingredients (API's) and their scale up to pilot plant and manufacturing. Study and control of critical parameters, impurities profile and stability using HPLC, GC, MS and NMR. Writing process description protocols, activity reports, drug master files (DMF's) in compliance with current regulatory requirements and industry standards.Achievements:  Successfully planned, develop and supervised the synthesis of two APIs for their scale-up and production at large scale (average batch size 100kg). Participating actively in transfer meetings with Pilot Plant and Manufacturing and supervising validation batches to ensure process robustness.  Compilation and edition of the corresponding Drug Master File according to ICH guidelines. Show less



Medichem, S.A.

• Spain
• Pharmaceutical Manufacturing
• 100 - 200 Employee

• Senior Research Development Chemist

  • Apr 2015 - Jan 2017

  Development, planning and validation of new routes for the synthesis of active pharmaceutical ingredients (API's) and their scale up to pilot plant and manufacturing. Study and control of critical paremetres, impurities profile and stability using HPLC, GC, MS and NMR. Writting process description protocols, activity reports, drug master files (DMF's) in compliance with current regulatory requirements and industry standards. Development, planning and validation of new routes for the synthesis of active pharmaceutical ingredients (API's) and their scale up to pilot plant and manufacturing. Study and control of critical paremetres, impurities profile and stability using HPLC, GC, MS and NMR. Writting process description protocols, activity reports, drug master files (DMF's) in compliance with current regulatory requirements and industry standards.



AstraZeneca

• United Kingdom
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Research Chemist

  • Jun 2012 - Apr 2015

  Development and planning of new routes for the synthesis of active pharmaceutical ingredients (API's) and their scale up to pilot plant for clinical studies. Study and control of critical parameters, end of reaction, impurities profile and final product using HPLC, GC, MS and NMR. Identify and engage in cross-disciplinary collaborations aimed at mechanistic understanding of impurities (kinetics) and scale up reproducibility (engineers). Write and follow standard operating procedures (SOP’s), process description protocols and activity reports in compliance with current regulatory requirements and industry standards. Achievements: Successfully planned and prioritised a synthetic route for the synthesis of API. Development of the scale up stage taking smart risk decisions based on chemistry knowledge. Delivery of proposed 500kg of API for clinical studies according to deadlines. Show less



AkzoNobel

• Netherlands
• Chemical Manufacturing
• 700 & Above Employee

• R&D Chemist

  • Feb 2011 - Jun 2012

  Development of new wood treatments to improve its physical (swelling, cracking) and chemical (biocide resistance, UV protection) properties, and new methodologies for the study of wood behaviour in different environments. Development of new wood treatments to improve its physical (swelling, cracking) and chemical (biocide resistance, UV protection) properties, and new methodologies for the study of wood behaviour in different environments.



Duke Chem S.A.

• Barcelona Area, Spain

• R&D Technician

  • Mar 2006 - Sep 2007

  Synthesis of active pharmaceutical ingredients (API’s) using organic tools (lithiation, halosulfonation, group protection, bromination). Design of new synthetic routes and executing the synthesis, optimising the process when necessary. Development the analytical methods (HPLC, IR and UV) for the relevant intermediates. Synthesis of active pharmaceutical ingredients (API’s) using organic tools (lithiation, halosulfonation, group protection, bromination). Design of new synthetic routes and executing the synthesis, optimising the process when necessary. Development the analytical methods (HPLC, IR and UV) for the relevant intermediates.



Enantia

• Spain
• Research Services
• 1 - 100 Employee

• R&D Chemist

  • Jan 2006 - Mar 2006

  Synthesis of new non-racemic organic compounds using Sharpless asymmetric epoxidation. Synthesis of new non-racemic organic compounds using Sharpless asymmetric epoxidation.



Puig

• Spain
• Retail Luxury Goods and Jewelry
• 700 & Above Employee

• Analytical Chemist

  • Jul 2004 - Aug 2004

  Summer placement at Puig cosmetics. Analysis of raw materials and final products using: HPLC, GC, UV, Karl-Fischer and IR. Summer placement at Puig cosmetics. Analysis of raw materials and final products using: HPLC, GC, UV, Karl-Fischer and IR.