Experience

Karuna Therapeutics

• United States
• Biotechnology
• 100 - 200 Employee

• Senior Consultant

  • Sep 2021 - Present

  Lead/develop the pharmacogenomics, biomarkers, and translational-precision medicine in the Phase 3 trials. Chose and contracted vendors for patient blood sample storage, sequencing, analyses, and long-term data storage. Lead/develop the pharmacogenomics, biomarkers, and translational-precision medicine in the Phase 3 trials. Chose and contracted vendors for patient blood sample storage, sequencing, analyses, and long-term data storage.



AdvisoryCloud

• United States
• Business Consulting and Services
• 500 - 600 Employee

• Advisor

  • Nov 2019 - Present



Biotech Clinical Research (BBCR)

• Boston, Massachusetts, United States

• Healthcare Consultant

  • Mar 2022 - Jun 2022

  Lead and develop the write-up for two Phase 1 clinical trials and design the biomarker program for a biotech company. Lead and develop the write-up for two Phase 1 clinical trials and design the biomarker program for a biotech company.



Takeda

• Japan
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Director, Translational Biomarker Research

  • Feb 2013 - Sep 2019

  Provide the global leadership and oversight of the Neuroscience pharmcogenetic/genetics discovery activity in the Translational Biomarker Research division. Responsible for interfacing with the Neuroscience Pre-Clinical and ClinicalTherapeutic Area (TAU) units to initiate, design and develop target discovery programs in relevant disease areas with human samples. I also provide guidance to TAU program leaders on the incorporation of genetic collection activities into multiple clinical and pre-clinical programs. Show less



DemeRx Inc.

• 4400 Biscayne Avenue, Miami, FL 33137

• Director of Laboratory Services

  • Jun 2011 - Mar 2012

  Co-ordinate with, and advise the CSO and senior company members on all scientific knowledge regarding DemeRx’s clinical and research programs. Manage, negotiate and coordinate CRO work as well as collate/track/interpret all the scientific results. Synthesize, analyze, write and edit the scientific information related to drug abuse and the company’s lead addiction compound. Supervise the development/testing of new chemical entities related to a proprietary compound for drug abuse undergoing pre-clinical testing in preparation for first in man. Show less



Brain Endowment Bank,

• Dept. of Neurology, University of Miami, 1951 NW 7th Avenue, Miami, FL 33136

• Director of Research

  • Jun 2011 - Feb 2012

  Enhance and develop the communication network to broaden the awareness and collection of donors/specimens for the bank which includes neurodegenerative and psychiatric diseases and controls. Developed and expand scientific-clinical collaborations to enhance value and manage the research and development programs Enhance and develop the communication network to broaden the awareness and collection of donors/specimens for the bank which includes neurodegenerative and psychiatric diseases and controls. Developed and expand scientific-clinical collaborations to enhance value and manage the research and development programs



GeneLogic/Ocimum Biosolutions

• Director of Genomics Operations

  • Jun 2010 - Dec 2010

  Directed the Biorepository, operations, microarray and genomic services and led R & D efforts supporting and developing new technologies and products in GLP and non-GLP laboratories. Lead person assisting sales and marketing, communicated and presented proposals and and solutions to clients and senior management. Managed budgets and prioritized projects and a staff of 30 to maximize work flow and realize targeted outcomes. Lead the bioinformatics group. Ensured all aspects of facility operations were conducted in accordance to all applicable federal and local agencies and regulations Show less



Gene Logic

• United States
• Biotechnology
• 1 - 100 Employee

• Scientific Director

  • Feb 2001 - Dec 2010

  Lead scientist/manager for internal and external genomics R & D activities. Designed, developed and implemented a human Central Nervous System (CNS) gene expression database which included multiple diseases and controls. Developed and maintained external partners for tissue accrual and scientific collaborations. Primary liaison regarding communication-sales-marketing with scientific and business clients and routinely provided the scientific briefing to the Board of Directors and Senior Management. Multiple peer reviewed publications and scientific presentations throughout the pharmaceutical industry to support revenue generation >$75M. Remained abreast of all genomic technologies and implemented technologies/platforms as appropriate. Managed and partnered with external/internal teams to accomplish program developments Show less



AstraZeneca

• United Kingdom
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Research Scientist

  • Apr 1998 - 2000

  Senior Research Bioscientist Selected/recruited to provide expertise and collaborative leadership to implement and develop the Metabolism Exploratory Group in Manchester England . Senior Research Bioscientist Selected/recruited to provide expertise and collaborative leadership to implement and develop the Metabolism Exploratory Group in Manchester England .



Zeneca Pharmaceuticals.

• Wilmington, DE.

• Senior Research Scientist

  • Sep 1991 - Apr 1998

  As project/study leader for several research programs involving obesity, anxiety/depression, analgesia and stroke, designed, implemented and managed the scientific processes for each study. Championed and developed the first target discovery and validation program on CNS mechanisms in obesity/cachexia. Developed the first CNS division integrative and multidisciplinary strategy; this was organized through supracellular (in vivo behavioral analysis), cellular (electrophysiological/pharmacological-patch clamp) and molecular (DNA, RNA and protein analyses) approaches. Initiated and led other CNS discovery and validation programs and managed external CNS business collaborations and a member in the CNS management advisory team. Directed six staff and three post-doctoral fellows and provided indirect management to other research groups. Show less



ICI Pharmaceuticals

• Wilmington, DE

• Research Scientist

  • Aug 1989 - Sep 1991

  Established and developed the first company in vitro CNS electrophysiology/ pharmacology laboratories with a staff of three. Patch-clamp whole-cell recordings of calcium and ligand gated currents in acutely dissociated rat hippocampal CA1 neurons, cultured rat hippocampal and dorsal root ganglion neurons. • Discovered and characterized the novel action of Neurosteroids on specific neuronal voltage-gated calcium channels. • Discovered and characterized the novel action of the Barbiturates on specific voltage-gated calcium currents. • Discovered and characterized the novel action of Phencyclidine (PCP) on specific voltage-gated calcium currents. • Developed a fresh dissociation procedure to obtain rat dorsal root ganglion neurons Show less



NIH Research & Consulting

• United States
• Market Research
• 100 - 200 Employee

• Post-Doctoral Fellow

  • Mar 1987 - Aug 1989

  Electrophysiological/pharmacological patch clamp studies: action of phencyclidine (PCP) on neuronal voltage-gated potassium channels. N. Barker, M.D. & M.A.Rogawski, M.D., Ph.D. Electrophysiological/pharmacological patch clamp studies: action of phencyclidine (PCP) on neuronal voltage-gated potassium channels. N. Barker, M.D. & M.A.Rogawski, M.D., Ph.D.



The Johns Hopkins University, School of Medicine

• Baltimore, MD

• Post Doctoral Fellow

  • 1984 - 1987

  Electrophysiological/pharmacological in vitro studies: excitatory amino acids in epilepsy. R.S.Fisher, M.D., Ph.D. and J. T. Coyle, M.D Electrophysiological/pharmacological in vitro studies: excitatory amino acids in epilepsy. R.S.Fisher, M.D., Ph.D. and J. T. Coyle, M.D



Ciba-Geigy

• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Consultant

  • 1984 - 1987

  Consulted on electrophysiological and pharmacological studies in collaboration with the chemistry department to examine the chemistry of new compounds interacting with the excitatory amino acid transmitter receptors. Consulted on electrophysiological and pharmacological studies in collaboration with the chemistry department to examine the chemistry of new compounds interacting with the excitatory amino acid transmitter receptors.



Kyusu University, Kyushu, Japan

• Research Fellow

  • Jul 1986 - Dec 1986

  Electrophysiological patch clamp studies on neuronal GABA-A receptors. Member of the team that developed the acute dissociation technique to obtain freshly isolated neurons. N. Akaike, Ph.D Electrophysiological patch clamp studies on neuronal GABA-A receptors. Member of the team that developed the acute dissociation technique to obtain freshly isolated neurons. N. Akaike, Ph.D