Jan Hendriks
Senior Research Development Scientist at Orthros Medical- Claim this Profile
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Experience
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Orthros Medical
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Netherlands
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Biotechnology Research
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1 - 100 Employee
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Senior Research Development Scientist
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Dec 2022 - Present
Development of Llama antibody therapies for treatment of chronic and acute diseases Development of Llama antibody therapies for treatment of chronic and acute diseases
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University of Twente
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Netherlands
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Research Services
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700 & Above Employee
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Postdoctoral Scientist
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Dec 2021 - Present
Research on early diagnostics and new treatment options for chronic diseases Research on early diagnostics and new treatment options for chronic diseases
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UMC Utrecht
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Hospitals and Health Care
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1 - 100 Employee
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Senior Research Development Scientist
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May 2021 - Dec 2021
Development of early diagnostics for osteoarthritis Development of early diagnostics for osteoarthritis
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Postdoctoral Scientist
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Mar 2018 - Apr 2021
Research on early diagnostics and new treatment options for osteoarthritis
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PhD
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Feb 2014 - Feb 2018
Osteoarthritis is a debilitating disease affecting millions worldwide. The disease has many phenotypes, but a strong risk factor is a history of trauma in the affected joint. Early stage monitoring and treatment of these patients might be able to slow of avoid the development of this disease. However no minimal-invasive technique is currently available that is capable of diagnosing this early stage.When the joint is affected the homeostasis of the tissue will change. This leads to an altered metabolism and possible inflammation. The synovial fluid is in contact with all joint tissues and has an important messenger function. It is therefore likely that changes in joint homeostasis leads to altered marker concentrations in this fluid. With a needle small volumes can be extracted minimal invasively. The subsequent analysis of the marker concentration is a potentially powerful tool for early stage diagnosis and prognosis.The goals of this PhD track are two-fold. First a sensitive lab-on-chip based system will be developed with which a large array of markers can be detected sensitively and selectively in trace concentrations at low costs. When a reliable system has been developed and validated, the second phase of the project will start. Here a database of marker profiles of healthy and diseased synovial fluid will be created as a benchmarking tool. Patient profiles can be compared with this benchmark for diagnosis, prognosis and potentially even treatment. Show less
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Student assistant Practical courses
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Jan 2011 - Jan 2014
Support students in numerous practical courses
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StudiQ
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United Kingdom
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Wellness and Fitness Services
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Student coach
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Jan 2012 - Jan 2014
To support secondary school students with homework planning, exam training and to provide guidance to help them understand their courses. To support secondary school students with homework planning, exam training and to provide guidance to help them understand their courses.
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University of Liverpool
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United Kingdom
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Higher Education
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700 & Above Employee
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Scientist
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Feb 2012 - Jun 2012
Research on in situ gelating hydrogels for adipose tissue engineering in reconstructive surgery Research on in situ gelating hydrogels for adipose tissue engineering in reconstructive surgery
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Education
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University of Twente
Master of Science, Biomedical Engineering