Experience

PureTech Health

• United States
• Biotechnology
• 1 - 100 Employee

• Senior Director, Medicinal Chemistry

  • Jan 2022 - Present

• Director Medicinal Chemistry

  • Jan 2020 - Dec 2021

• Associate Director Medicinal Chemistry

  • Jan 2019 - Dec 2019

• Principal Scientist

  • Oct 2017 - Jan 2019

  Chemistry Lead in the development of lipid prodrug technology platform.



Monash University

• Australia
• Higher Education
• 700 & Above Employee

• Adjunct Senior Research Fellow

  • Jan 2018 - 2019

  Adjunct research position. Continuing collaboration with PhD students and academic groups at Monash University in lipid prodrug technology.

• Adjunct Senior Lecturer

  • Jan 2015 - Jan 2018

  Adjunct research position. Continuing collaboration with PhD students and academic groups at Monash University in fragment-based drug discovery, lipid prodrugs and bioactive natural products.

• Senior Lecturer

  • Jan 2012 - Jan 2015

  Teaching and research academic position. Teaching organic and medicinal chemistry and drug discovery to all levels of undergraduate courses in pharmaceutical science and pharmacy, through multiple teaching modalities. Implemented active learning approaches. Research in fragment-based drug discovery, antiinfective drug discovery, prodrugs, natural products chemistry, click chemistry. Led a research group of up to 15 honours, PhD and postdoctoral researchers. Attracted >$2.5 million AUD… Show more Teaching and research academic position. Teaching organic and medicinal chemistry and drug discovery to all levels of undergraduate courses in pharmaceutical science and pharmacy, through multiple teaching modalities. Implemented active learning approaches. Research in fragment-based drug discovery, antiinfective drug discovery, prodrugs, natural products chemistry, click chemistry. Led a research group of up to 15 honours, PhD and postdoctoral researchers. Attracted >$2.5 million AUD in collaborative research grants. Published 17 peer-reviewed publications (2012-2015).

• Lecturer

  • Nov 2004 - Dec 2011

  Teaching and research academic position. Teaching organic and medicinal chemistry and drug discovery to all levels of undergraduate courses in pharmaceutical science and pharmacy, through multiple teaching modalities. Implemented active learning approaches. Research in fragment-based drug discovery, antiinfective drug discovery, prodrugs, natural products chemistry, click chemistry. led a research group of up to 15 honours, PhD and postdoctoral researchers. Published 18 peer-reviewed… Show more Teaching and research academic position. Teaching organic and medicinal chemistry and drug discovery to all levels of undergraduate courses in pharmaceutical science and pharmacy, through multiple teaching modalities. Implemented active learning approaches. Research in fragment-based drug discovery, antiinfective drug discovery, prodrugs, natural products chemistry, click chemistry. led a research group of up to 15 honours, PhD and postdoctoral researchers. Published 18 peer-reviewed publications.



Glyph Biosciences, Puretech Health

• Principal Scientist

  • Oct 2017 - Jul 2018

  Chemistry Lead in the development of lipid prodrug technology platform. Chemistry Lead in the development of lipid prodrug technology platform.



AstraZeneca

• United Kingdom
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Scientist Medicinal Chemistry

  • Feb 2016 - Jul 2016

  Member of the Fragment-Based Lead Generation Chemistry team, tasked with developing fragment hits into potent lead quality compound series. The approach employs a collaborative combination of structure-based design, computational chemistry, chemical synthesis (mostly CRO), and analysis of assay results to drive further compound design towards desired project compound criteria of potency, selectivity and physicochemical properties. Contributed to three projects before the group was… Show more Member of the Fragment-Based Lead Generation Chemistry team, tasked with developing fragment hits into potent lead quality compound series. The approach employs a collaborative combination of structure-based design, computational chemistry, chemical synthesis (mostly CRO), and analysis of assay results to drive further compound design towards desired project compound criteria of potency, selectivity and physicochemical properties. Contributed to three projects before the group was relocated/closed for business reasons. Show less Member of the Fragment-Based Lead Generation Chemistry team, tasked with developing fragment hits into potent lead quality compound series. The approach employs a collaborative combination of structure-based design, computational chemistry, chemical synthesis (mostly CRO), and analysis of assay results to drive further compound design towards desired project compound criteria of potency, selectivity and physicochemical properties. Contributed to three projects before the group was… Show more Member of the Fragment-Based Lead Generation Chemistry team, tasked with developing fragment hits into potent lead quality compound series. The approach employs a collaborative combination of structure-based design, computational chemistry, chemical synthesis (mostly CRO), and analysis of assay results to drive further compound design towards desired project compound criteria of potency, selectivity and physicochemical properties. Contributed to three projects before the group was relocated/closed for business reasons. Show less



Vertex Pharmaceuticals

• United States
• Biotechnology Research
• 700 & Above Employee

• Visiting Scientist

  • Jul 2013 - Jan 2014

  Sabbatical leave from Monash University, aspects of fragment-based drug discovery, synthetic medicinal chemistry. Sabbatical leave from Monash University, aspects of fragment-based drug discovery, synthetic medicinal chemistry.



University of Cambridge

• United Kingdom
• Research Services
• 700 & Above Employee

• Marie Curie Research Fellow

  • Apr 2004 - Nov 2004

  Design, synthesis and assay of inhibitors of the pantothenate pathway. Experience with protein expression and purification, computational docking, enzyme assays, medicinal chemistry. Design, synthesis and assay of inhibitors of the pantothenate pathway. Experience with protein expression and purification, computational docking, enzyme assays, medicinal chemistry.



Australian National University

• Australia
• Higher Education
• 700 & Above Employee

• Postdoctoral Research Fellow/Research Fellow

  • Jan 2001 - Apr 2004

  Research in biochemistry, organic chemistry, physical organic chemistry. experience with cyclodextrin chemistry, amino acid and peptide synthesis, enzyme assay development, enzyme inhibitor design, medicinal chemistry, free-radical chemistry. Research in biochemistry, organic chemistry, physical organic chemistry. experience with cyclodextrin chemistry, amino acid and peptide synthesis, enzyme assay development, enzyme inhibitor design, medicinal chemistry, free-radical chemistry.