James Dowell
Scientific Director at Immuto Scientific- Claim this Profile
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Experience
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Immuto Scientific
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United States
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Biotechnology Research
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1 - 100 Employee
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Scientific Director
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May 2022 - Present
-Lead research and development efforts -Develop business strategies for drug discovery services -Interface with clients on project design and execution -Train and mentor junior staff -Lead research and development efforts -Develop business strategies for drug discovery services -Interface with clients on project design and execution -Train and mentor junior staff
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Arrowhead Pharmaceuticals
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United States
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Pharmaceutical Manufacturing
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200 - 300 Employee
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Senior Scientist II
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Nov 2021 - May 2022
-Managed multiple projects in preclinical DMPK to support drug candidate selection program -Performed pharmacokinetic analysis of siRNA-based drug candidates via mass spectrometry -Acted as subject matter liaison between discovery chemistry and CNS biology teams -Managed multiple projects in preclinical DMPK to support drug candidate selection program -Performed pharmacokinetic analysis of siRNA-based drug candidates via mass spectrometry -Acted as subject matter liaison between discovery chemistry and CNS biology teams
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Wisconsin Institute for Discovery
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United States
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Research
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1 - 100 Employee
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Research Scientist
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Sep 2012 - Oct 2021
-Managed mass spectrometry core and associated collaborations within Epigenetics Theme -Trained and mentored over a dozen graduate students in proteomics, metabolomics, and molecular biology -Authored and co-authored NIH grants -Developed and implemented novel mass spectrometry methods for the analysis of epigenetic alterations in Alzheimer's disease -Managed mass spectrometry core and associated collaborations within Epigenetics Theme -Trained and mentored over a dozen graduate students in proteomics, metabolomics, and molecular biology -Authored and co-authored NIH grants -Developed and implemented novel mass spectrometry methods for the analysis of epigenetic alterations in Alzheimer's disease
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Waisman Center
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United States
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Research Services
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1 - 100 Employee
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Research Scientist
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Sep 2011 - Aug 2012
-Validated proteomics-identified targets via molecular biological techniques -Mentored junior staff members -Identified targets of c-Jun terminal kinase and their role in Fragile X syndrome via quantitative proteomics -Validated proteomics-identified targets via molecular biological techniques -Mentored junior staff members -Identified targets of c-Jun terminal kinase and their role in Fragile X syndrome via quantitative proteomics
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University of Wisconsin
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Higher Education
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700 & Above Employee
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Post-Doctoral Fellow
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Sep 2008 - Sep 2011
-Identified key neuroprotective enzymes via quantitative proteomics, bioinformatics, molecular biology, and enzymatic assays -Trained graduate students in cell culturing and molecular biology techniques -Wrote independent grant proposals and original scientific manuscripts
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Doctoral Researcher
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Aug 2003 - Aug 2008
-Developed novel mass spectrometry methods for the analysis of mammalian neuropeptides -Taught laboratory classes in drug delivery and pharmaceutical biochemistry
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ICOS Corporation
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United States
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Pharmaceutical Manufacturing
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Quality Control Associate
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Aug 2000 - Jul 2003
-Developed analytical methods for the analysis of small molecule and protein drugs in a GMP environment -Directed junior scientists in the testing of small molecules and biopharmaceuticals -Developed analytical methods for the analysis of small molecule and protein drugs in a GMP environment -Directed junior scientists in the testing of small molecules and biopharmaceuticals
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Education
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University of Wisconsin-Madison
Doctor of Philosophy - PhD, Pharmaceutical Sciences