James Dowell

Scientific Director at Immuto Scientific
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Location
Madison, Wisconsin, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientific Director
      • May 2022 - Present

      -Lead research and development efforts -Develop business strategies for drug discovery services -Interface with clients on project design and execution -Train and mentor junior staff -Lead research and development efforts -Develop business strategies for drug discovery services -Interface with clients on project design and execution -Train and mentor junior staff

    • United States
    • Pharmaceutical Manufacturing
    • 200 - 300 Employee
    • Senior Scientist II
      • Nov 2021 - May 2022

      -Managed multiple projects in preclinical DMPK to support drug candidate selection program -Performed pharmacokinetic analysis of siRNA-based drug candidates via mass spectrometry -Acted as subject matter liaison between discovery chemistry and CNS biology teams -Managed multiple projects in preclinical DMPK to support drug candidate selection program -Performed pharmacokinetic analysis of siRNA-based drug candidates via mass spectrometry -Acted as subject matter liaison between discovery chemistry and CNS biology teams

    • United States
    • Research
    • 1 - 100 Employee
    • Research Scientist
      • Sep 2012 - Oct 2021

      -Managed mass spectrometry core and associated collaborations within Epigenetics Theme -Trained and mentored over a dozen graduate students in proteomics, metabolomics, and molecular biology -Authored and co-authored NIH grants -Developed and implemented novel mass spectrometry methods for the analysis of epigenetic alterations in Alzheimer's disease -Managed mass spectrometry core and associated collaborations within Epigenetics Theme -Trained and mentored over a dozen graduate students in proteomics, metabolomics, and molecular biology -Authored and co-authored NIH grants -Developed and implemented novel mass spectrometry methods for the analysis of epigenetic alterations in Alzheimer's disease

    • United States
    • Research Services
    • 1 - 100 Employee
    • Research Scientist
      • Sep 2011 - Aug 2012

      -Validated proteomics-identified targets via molecular biological techniques -Mentored junior staff members -Identified targets of c-Jun terminal kinase and their role in Fragile X syndrome via quantitative proteomics -Validated proteomics-identified targets via molecular biological techniques -Mentored junior staff members -Identified targets of c-Jun terminal kinase and their role in Fragile X syndrome via quantitative proteomics

    • Higher Education
    • 700 & Above Employee
    • Post-Doctoral Fellow
      • Sep 2008 - Sep 2011

      -Identified key neuroprotective enzymes via quantitative proteomics, bioinformatics, molecular biology, and enzymatic assays -Trained graduate students in cell culturing and molecular biology techniques -Wrote independent grant proposals and original scientific manuscripts

    • Doctoral Researcher
      • Aug 2003 - Aug 2008

      -Developed novel mass spectrometry methods for the analysis of mammalian neuropeptides -Taught laboratory classes in drug delivery and pharmaceutical biochemistry

    • United States
    • Pharmaceutical Manufacturing
    • Quality Control Associate
      • Aug 2000 - Jul 2003

      -Developed analytical methods for the analysis of small molecule and protein drugs in a GMP environment -Directed junior scientists in the testing of small molecules and biopharmaceuticals -Developed analytical methods for the analysis of small molecule and protein drugs in a GMP environment -Directed junior scientists in the testing of small molecules and biopharmaceuticals

Education

  • University of Wisconsin-Madison
    Doctor of Philosophy - PhD, Pharmaceutical Sciences
    2003 - 2008

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