Experience

Mural Oncology

• United States
• Biotechnology Research
• 1 - 100 Employee

• Associate Principal Scientist

  • Nov 2023 - 2 months

  Waltham, Massachusetts, United States



Alkermes

• Ireland
• Biotechnology Research
• 700 & Above Employee

• Associate Principal Scientist

  • Mar 2023 - Nov 2023

  Waltham, Massachusetts, United States

• Senior Scientist

  • Jul 2021 - Mar 2023

  Waltham, Massachusetts, United States -Senior Scientist in the Analytical Development department -Leads analytical development strategy for verification/validation and implementation of release and stability methods for a diluent used along side a protein therapy, to be submitted as part of a biologics license application (BLA). Work was highly collaborative across functions (AD, QA, QC, Regulatory, CMC) and included at overseeing work at multiple CROs. -Leads a small group within analytical development focusing on method… Show more -Senior Scientist in the Analytical Development department -Leads analytical development strategy for verification/validation and implementation of release and stability methods for a diluent used along side a protein therapy, to be submitted as part of a biologics license application (BLA). Work was highly collaborative across functions (AD, QA, QC, Regulatory, CMC) and included at overseeing work at multiple CROs. -Leads a small group within analytical development focusing on method development and execution of analytical testing to support both early and late stage projects

• Scientist

  • Jul 2019 - Jul 2021

  Waltham, Massachusetts, United States -Scientist in the Pharmaceutical Chemistry and Formulation Development Department (July 2019 - October 2019) and Analytical Development (October 2019 - July 2021) -Drafted study protocols, led analytical studies, and worked closely with CROs in a highly collaborative environment -Performed analytical method development, focusing on protein higher order structure and physiochemical characterization, and drafted SOPs and technical reports -Employed statistical thinking and problem… Show more -Scientist in the Pharmaceutical Chemistry and Formulation Development Department (July 2019 - October 2019) and Analytical Development (October 2019 - July 2021) -Drafted study protocols, led analytical studies, and worked closely with CROs in a highly collaborative environment -Performed analytical method development, focusing on protein higher order structure and physiochemical characterization, and drafted SOPs and technical reports -Employed statistical thinking and problem solving in analysis of experimental data using JMP -Performed routine characterization of biologics drug substance and drug product, including KF moisture analysis, HPLC, and other methods -Involved in the creation and implementation of strategies for improved lab automation, data processing, and data governance -Developed formulations for biologics through screening and physiochemical characterization -Explored the preparation and functionalization of polymeric nanoparticles for drug delivery -Applied knowledge of crystal form behavior to the development and understanding of drug products -Studied the formation of solid solutions of structurally similar molecules with divergent crystal form diversity, resulting in a publication



Fors Research Group, Cornell University

• Graduate Research Assistant

  • Aug 2014 - Jun 2019

  Ithaca, NY -Thesis: Renewable Polymers from Itaconic Acid -Performed small molecule and polymer synthesis, structure characterization, and physical property analysis, particularly using and developing green and sustainable practices, resulting in several publications -Participated in highly collaborative research through major involvement in the Center for Sustainable Polymers -Advised by Professor Brett Fors.



Villanova University Department of Chemistry

• Research Assistant

  • Jan 2014 - May 2014

  Villanova, PA Under the supervision of Nicholas Piro, Ph. D., synthesized organic guanidine ligands and complexed them with various metals for the formation of organometallic compounds with unique coordination geometries and properties.



Alkermes, Inc

• Intern

  • May 2011 - May 2014

  Waltham, MA -Over one year cumulative work experience in the pharmaceutical industry (2011: May – August, December; 2012: January, May – August; 2013: January – March, December; 2014: January, May – July) under the supervision of Tarek Zeidan, Ph. D. -Responsible for crystal form exploration of Dehydro-Aripiprazole, the active metabolite of Aripiprazole. Responsible for a variety of polymorph, solvate, hydrate, and salt screens for pharmaceutically relevant compounds, as well as the utilization of… Show more -Over one year cumulative work experience in the pharmaceutical industry (2011: May – August, December; 2012: January, May – August; 2013: January – March, December; 2014: January, May – July) under the supervision of Tarek Zeidan, Ph. D. -Responsible for crystal form exploration of Dehydro-Aripiprazole, the active metabolite of Aripiprazole. Responsible for a variety of polymorph, solvate, hydrate, and salt screens for pharmaceutically relevant compounds, as well as the utilization of crystal engineering techniques for the production of desired API crystal properties. -Work resulted in several publications. Show less