In vivo Operations Manager

• Dec 2022 - Present

We deliver a comprehensive range of non-clinical research services for all biomedical products with the highest data quality and integrity, focused on timely communication and exemplary customer service, to better predict human outcomes. We deliver a comprehensive range of non-clinical research services for all biomedical products with the highest data quality and integrity, focused on timely communication and exemplary customer service, to better predict human outcomes.

Associate Scientist II

• Aug 2022 - Oct 2022

Project Manager

• Mar 2022 - Aug 2022

Associate Scientist II

• Aug 2018 - Mar 2022

Member of the Research and Development team tasked with coordinating all phases of research & development projects in expanding and emboldening company’s immunotherapy pipelines. Providing project management support encompassing management of R&D project timelines, of team’s operational and logistical plans, and of execution on strategies and critical paths as they relate to time-sensitive milestones. In addition, implementing cross-functional support for the Clinical Science group with assay development, and data management; also providing technical expertise and mentorship to junior research members.

Associate Scientist

• Feb 2017 - Jun 2018

Member of an interdepartmental team tasked with elucidating the mechanism of action of RXDX-106 as a tumor suppressor with immuno-oncological potential, leading to a successful IND filing with the FDA, and the start of a Phase I clinical trial. Member of an interdepartmental team tasked with elucidating the mechanism of action of RXDX-106 as a tumor suppressor with immuno-oncological potential, leading to a successful IND filing with the FDA, and the start of a Phase I clinical trial.

Senior Research Associate

• Sep 2016 - Dec 2016

Member of the Discovery Research department, responsible for developing in vitro assays, generating and analyzing data for the Molecular Biology group, tasked with improving clinical immuno-oncology strategies as well as designing new therapeutic candidates. Member of the Discovery Research department, responsible for developing in vitro assays, generating and analyzing data for the Molecular Biology group, tasked with improving clinical immuno-oncology strategies as well as designing new therapeutic candidates.

Senior Research Associate

• Nov 2013 - Sep 2016

Member and team leader of multiple cross-functional projects in developing a blood-based colorectal cancer laboratory developed test. Also, managed technical troubleshooting and support for clinical operations. Member and team leader of multiple cross-functional projects in developing a blood-based colorectal cancer laboratory developed test. Also, managed technical troubleshooting and support for clinical operations.

Lab Manager and Senior Research Associate

• Feb 2005 - Aug 2013

Lead personnel of laboratory’s expertise in shear-dependent cellular trafficking, transendothelial migration (TEM) and other in vitro shear-based assays. I also managed the overall, day-to-day laboratory operations and fostered communications within the laboratory group but also with outside collaborators. • Pioneered adaptations to the Transendothelial Migration Chamber (TEMC) to accommodate rapid modulations of chemokine gradients across endothelial monolayers, mimicking the physiological environment. • Led a study to elucidate T-cell TEM and retrograde TEM in response to rapid changes in chemokine gradients. • Oversaw a collaborative project in revealing CD4 T-cell trafficking and accumulation in response to soluble HIV-1 gp120. • Designed and spearheaded experiments to observe granulocyte adhesion deficiencies in CDG2c/LAD2 patients. • Supported other projects studying trafficking of lymphoma cells, modified mesenchymal stem cells and hematopoietic progenitor cells. • Supervised the fusion, screening and maintenance of hybridoma cell lines, producing monoclonal antibodies specific to a glycoform of CD44, Hematopoietic Cell E-/L-selectin Ligand (HCELL). • Developed protocols for purifying monoclonal antibodies from hybridoma cell culture supernatants. • Contributed to the studies of ex vivo glycosylation of cell surface proteins to enhance trafficking of mesenchymal stem cells. • Communicated with international laboratories to negotiate custom production and shipment of reagents needed for studies. • Presented results, conclusions and discovery at weekly group meetings, and often at department meetings. • Managed the use and maintenance of laboratory’s flow cytometer (FC500MPL), cell culture facilities, and equipment for shear-based assays. • Responsible for writing, submitting, and updating laboratory’s IACUC animal protocols and IRB protocols. • Occasionally presided over group meetings, communicating timelines, progress updates and milestones.

Graduate Research Assistant

• Sep 2002 - Feb 2005

• Analyzed the protein and mRNA expressions of NOD2/CARD15, a pathogen recognition receptor (PRR), in various tissue-specific endothelial cells in studying the autoinflammatory disorder, Blau syndrome. • Awarded sponsorship through the university’s Ophthalmology Training Grant. • Analyzed the protein and mRNA expressions of NOD2/CARD15, a pathogen recognition receptor (PRR), in various tissue-specific endothelial cells in studying the autoinflammatory disorder, Blau syndrome. • Awarded sponsorship through the university’s Ophthalmology Training Grant.

Technical Research Assistant

• Mar 1999 - Aug 2002

• Assisted in identifying and biochemically characterizing a novel cell surface homing glycoprotein, HCELL, expressed on hematopoietic stem cells and leukemic blasts. • Facilitated the development of a flow-based assay, the blot-rolling assay, used for the identification of adhesion molecules capable of selectin-mediated binding. • Managed day-to-day operations of the laboratory, including ordering supplies and maintaining equipment. • Responsible for mentoring and managing summer students every year.