Experience

EMQN (European Molecular Genetics Quality Network)

• EQA Scientist

  • Jul 2019 - Present



Hologic, Inc.

• United States
• Medical Equipment Manufacturing
• 700 & Above Employee

• Senior Scientist

  • Sep 2014 - May 2019

  • Performing variety of microarray processing, qPCR, NGS and Sanger Sequencing and DNA and RNA extractions in support of client biomarker discovery and validation studies as well as supporting client clinic genomics programmes • Development and validation of customised assays, from research, design and execution to data interpretation• Carrying out all activities in accordance with the relevant quality standards, ISO17025 and GCP• Liaise with Technical Support and Engineering Teams to resolve technical issues and troubleshoot accordingly • Actively participate in process improvement program• Training and supervision of junior scientists • Line management• Participating in client meeting alongside project Manager and Business Development Team



All Wales Medical Genetics Service, University Hospital of Wales

• Genetic Technologist

  • Sep 2011 - Sep 2014

  • Rotational role between the various sections of the medical genetics laboratory• Carried out molecular genetic testing to achieve accurate genetic diagnoses within strict turnaround times: - Molecular pathology testing of tumour DNA samples, involving pyrosequencing and fragment analysis of diagnostic samples to direct personalised cancer treatment, or research samples for a large Cancer Research UK-funded project (the Stratified Medicine Programme) - Sanger sequencing analysis for diagnostic testing of early-onset epilepsy and development of Fluidigm target enrichment and Illumina MiSeq Next Generation Sequencing for analysis of inherited breast and ovarian cancer • Other duties included: - Sample receipt, sample preparation including DNA extraction, experimental setup, data analysis, quality assessment and troubleshooting, and clinical reporting - Dealing with enquiries from referring hospitals and other laboratories regarding diagnostic KRAS testing - Contribute to QA by reviewing and updating SOPs, and participate in EQA and NEQAS - Provide training and supervision to other members of staff - Involved in the evaluation and introduction of new laboratory services and technologies including automated pyrosequencing setup using the Hamilton STARlet liquid handling robot



West Midlands Regional Genetics Laboratory, Birmingham Women’s Hospital

• Healthcare Science Practitioner Trainee

  • Sep 2009 - Sep 2011

  • Two-year technical training position in a CPA accredited diagnostic genetics laboratory• Role involved a combination of academic and practical training across Cytogenetic and Molecular Genetics sections• Competency assessment through verbal, practical and written examinations and preparation of an online portfolio • Sample receipt, preparation and processing• Data analysis and reporting on the results to referring clinicians• Quality assessment of data and troubleshooting



National Institute for Medical Research, Virology Division

• Sandwich Course Student

  • Jul 2007 - Sep 2008

  • Work on the project: ‘Studies of the effects of mutations on drug-sensitivity of influenza viruses’. • Performed a range of molecular techniques including site-specific mutagenesis, molecular cloning, DNA and RNA extraction, quantification and purification, PCR, RT-PCR and DNA sequencing. • Performed protein experiments including Western blotting and fluorescence microscopy and virological procedures including cell transfection to produce recombinant viruses, haemagglutination tests, plaque assays, and mammalian cell culture.