Experience

WM-Therapeutics

• Germany
• Biotechnology Research
• 1 - 100 Employee

• Co-founder, Head of Discovery Biology

  • Jun 2021 - Present

  Responsible for development of drug‐research programs in the areas ofepigenetical regulation of cancer, metabolism and inflammation using small molecules.

• Co‐founder

  • Jul 2020 - May 2021



Phenex Pharmaceuticals AG

• Germany
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist

  • Nov 2019 - Jul 2020



SolMic Research GmbH

• Germany
• Biotechnology Research
• 1 - 100 Employee

• Head of Laboratory

  • Jan 2019 - Oct 2019

  Development of molecular biology approaches to identify mode of action of herbal extracts in the treatment of cancer, inflammation and metabolic disorders, and translation of them into new product ideas. Development of molecular biology approaches to identify mode of action of herbal extracts in the treatment of cancer, inflammation and metabolic disorders, and translation of them into new product ideas.



EMBL

• Germany
• Research Services
• 700 & Above Employee

• Project Leader

  • Jul 2016 - Dec 2018

  Elucidation of molecular mechanisms of tumour metabolism regulation.Management and Project Leading Experience:• Management: supervised and coached PhD, masters and internship students to successful theses completion. Successfully led recruitment efforts into the lab, resulting in direct supervision and training of new lab members• Finances: met financial and budgetary responsibility for internal and external research projects• Project Management: proven success in developing and achieving project schedules and milestone delivery• Business Development and Marketing: experience presenting and pitching projects to possible investors• Communication skills: exemplary communication, interpersonal and problem-solving skillsTechnical and Laboratory Proficiencies:• strong background in biochemistry and molecular/cellular biology• design and performance of phenotypic screens assays • CRISPR technology: design and creation of stable knock-in cell lines, mono- and polyclonal dual reporter cell lines • genome wide massively parallel sequencing and analysis: RNAseq, ChIPseq, MBDseq, bisulfite sequencing • numerous tissue culture techniques • molecular cloning• protein expression and purification, protein analytics, antibody generation• immunoprecipitation, SILAC, mass-spectrometry • luciferase assays, ELISA• immunofluorescence, confocal microscopy



Institute of Molecular Biology (IMB)

• Germany
• Research
• 100 - 200 Employee

• Postdoc

  • Jun 2011 - Jun 2016

  Small molecules-modulated gene expression Small molecules-modulated gene expression



DKFZ German Cancer Research Center

• Germany
• Research Services
• 700 & Above Employee

• Postdoc

  • May 2010 - Jun 2011

  Small molecules-modulated active DNA demethylation Small molecules-modulated active DNA demethylation



Max Planck Institute

• Research Services
• 200 - 300 Employee

• Bridging postdoc

  • Oct 2009 - May 2010

  Dosage compensation in D. melanogaster Dosage compensation in D. melanogaster



EMBL

• Germany
• Research Services
• 700 & Above Employee

• PhD student / postdoc

  • Oct 2005 - Jan 2010

  During my work at EMBL I significantly contributed to the understanding of molecular mechanisms of dosage compensation in D. melanogaster. I purified and characterized a novel Non Specific Lethal (NSL) protein complex involved in general transcriptional regulation, and demonstrated the involvement of the histone acetyl transferase MOF, expanding the role of NSL beyond dosage compensation. During my work at EMBL I significantly contributed to the understanding of molecular mechanisms of dosage compensation in D. melanogaster. I purified and characterized a novel Non Specific Lethal (NSL) protein complex involved in general transcriptional regulation, and demonstrated the involvement of the histone acetyl transferase MOF, expanding the role of NSL beyond dosage compensation.



Københavns Universitet - University of Copenhagen

• Denmark
• Research
• 700 & Above Employee

• Summer student

  • Jun 2005 - Aug 2005

  DNA replication and genome stability in S. pombe DNA replication and genome stability in S. pombe



The University of Edinburgh

• United Kingdom
• Research Services
• 700 & Above Employee

• Summer student

  • Jun 2004 - Aug 2004

  Elg1-RFC and Ctf18-RFC in DNA replication and repair Elg1-RFC and Ctf18-RFC in DNA replication and repair