Experience

NeoTX Therapeutics LTD

• Israel
• Biotechnology
• 1 - 100 Employee

• Senior Researcher

  • Jul 2013 - Present

  - Develop cancer therapeutics with novel methods of Free Energy Perturbation and molecular simulation of the protein-ligand binding; - Apply traditional methods of in silico virtual screening; - Independently design, develop and execute research plans, contributing to multiple projects; - In collaboration with the team of medicinal chemists and crystallographers generate and computationally test new design hypotheses significantly speeding up the drug development process; - Improve… Show more - Develop cancer therapeutics with novel methods of Free Energy Perturbation and molecular simulation of the protein-ligand binding; - Apply traditional methods of in silico virtual screening; - Independently design, develop and execute research plans, contributing to multiple projects; - In collaboration with the team of medicinal chemists and crystallographers generate and computationally test new design hypotheses significantly speeding up the drug development process; - Improve drug discovery methods and atomistic Force Field models including employing the front edge AI/ML tools. Show less - Develop cancer therapeutics with novel methods of Free Energy Perturbation and molecular simulation of the protein-ligand binding; - Apply traditional methods of in silico virtual screening; - Independently design, develop and execute research plans, contributing to multiple projects; - In collaboration with the team of medicinal chemists and crystallographers generate and computationally test new design hypotheses significantly speeding up the drug development process; - Improve… Show more - Develop cancer therapeutics with novel methods of Free Energy Perturbation and molecular simulation of the protein-ligand binding; - Apply traditional methods of in silico virtual screening; - Independently design, develop and execute research plans, contributing to multiple projects; - In collaboration with the team of medicinal chemists and crystallographers generate and computationally test new design hypotheses significantly speeding up the drug development process; - Improve drug discovery methods and atomistic Force Field models including employing the front edge AI/ML tools. Show less



University of California, Davis

• United States
• Higher Education
• 700 & Above Employee

• Research And Development Specialist

  • Feb 2010 - May 2012

  - Investigated central enzymes of Cellular Energy Generating System: Cytochrome c oxidase (CcO) and Complex I by Molecular Dynamics simulations including Coarse Grain model; - Identified the essential misrepresentation of electronic polarization in the standard atomistic force field paradigm; - Developed a new method of Molecular Dynamics in Electronic Continuum; - Significantly improved the accuracy of molecular modeling of ions, ionic liquids and their solvation free energies.

• Postdoctoral Researcher

  • 2006 - 2010

  - Investigated central enzymes of Cellular Energy Generating System: Cytochrome c oxidase (CcO) and Complex I by Molecular Dynamics simulations including Coarse Grain model; - Identified the essential misrepresentation of electronic polarization in the standard atomistic force field paradigm; - Developed a new method of Molecular Dynamics in Electronic Continuum; - Significantly improved the accuracy of molecular modeling of ions, ionic liquids and their solvation free energies.